Search Results - "Lu, Pei Hua"

Triptonide inhibits human nasopharyngeal carcinoma cell growth via disrupting Lnc-RNA THOR-IGF2BP1 signaling by Wang, Shu-sheng, Lv, Yan, Xu, Xin-Chun, Zuo, Yun, Song, Yu, Wu, Ge-ping, Lu, Pei-Hua, Zhang, Zhi-qing, Chen, Min-Bin

“…Advanced stage nasopharyngeal carcinoma (NPC) has a poor prognosis. Triptonide (“TN”) is a small molecule monomer extract from the ancient Chinese herb…”
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Impact of TROP2 expression on prognosis in solid tumors: A Systematic Review and Meta-analysis by Zeng, Ping, Chen, Min-Bin, Zhou, Li-Na, Tang, Min, Liu, Chao-Ying, Lu, Pei-Hua

“…Over-expression of TROP2 (the trophoblast cell surface antigen 2) was reported to predict poor prognosis in various solid tumors in number of studies. However,…”
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Hematopoietic stem cell transplantation activity in China 2019: a report from the Chinese Blood and Marrow Transplantation Registry Group by Xu, Lan-Ping, Lu, Pei-Hua, Wu, De-Pei, Sun, Zi-Min, Liu, Qi-Fa, Han, Ming-Zhe, Zhang, Xi, Song, Yong-Ping, Song, Xian-Min, Hu, Jian-da, Huang, He, Lai, Yong-Rong, Wan, Ding-Ming, Chen, Jing, Li, Chun-Fu, Xia, Ling-Hui, Wang, Jing-Bo, Liu, Dai-Hong, Huang, Xiao-Jun

“…Between 2008 and 2019, 58,914 hematopoietic stem cell transplantations (HSCTs) were reported to the Chinese Blood and Marrow Transplantation Registry Group…”
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P53 status as a predictive biomarker for patients receiving neoadjuvant radiation-based treatment: a meta-analysis in rectal cancer by Chen, Min-Bin, Wu, Xiao-Yang, Yu, Rong, Li, Chen, Wang, Li-Qiang, Shen, Wei, Lu, Pei-Hua

“…Numerous studies have yielded inconsistent results regarding the relationship between p53 status and the response to neoadjuvant radiation-based therapy in…”
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Activation of AMP-activated protein kinase (AMPK) mediates plumbagin-induced apoptosis and growth inhibition in cultured human colon cancer cells by Chen, Min-Bin, Zhang, Yan, Wei, Mu-Xin, Shen, Wei, Wu, Xiao-Yang, Yao, Chen, Lu, Pei-Hua

“…Here we report that activation of AMP-activated protein kinase (AMPK) mediates plumbagin-induced apoptosis and growth inhibition in both primary cultured human…”
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Prognostic value of CD146 in solid tumor: A Systematic Review and Meta-analysis by Zeng, Ping, Li, Hai, Lu, Pei-Hua, Zhou, Li-Na, Tang, Min, Liu, Chao-Ying, Chen, Min-Bin

“…CD146, also known as melanoma cell adhesion molecule, was initially identified as a marker of melanoma progression and metastasis. Recently many clinical…”
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Itraconazole-Induced Inhibition on Human Esophageal Cancer Cell Growth Requires AMPK Activation by Chen, Min-Bin, Liu, Yuan-Yuan, Xing, Zhao-Yu, Zhang, Zhi-Qing, Jiang, Qin, Lu, Pei-Hua, Cao, Cong

“…We here evaluated the antiesophageal cancer cell activity by the antifungal drug itraconazole. Our results show that μg/mL concentrations of itraconazole…”
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BRDT promotes ovarian cancer cell growth by Chen, Ling, Cai, Shang, Wang, Jing-mei, Huai, Ying-ying, Lu, Pei-Hua, Chu, Qian

“…Bromodomain testis-specific factor (BRDT) is a member of the bromodomain and extra-terminal (BET) family proteins. Its expression and potential functions in…”
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Advances in the development of chimeric antigen receptor-T-cell therapy in B-cell acute lymphoblastic leukemia by Zhang, Xian, Li, Jing-Jing, Lu, Pei-Hua

“…CD19-targeted chimeric antigen receptor T-cell (CAR-T) therapy is effective in refractory/relapsed (R/R) B-cell acute lymphoblastic leukemia (B-ALL). This…”
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Glutamine synthetase down-regulation reduces astrocyte protection against glutamate excitotoxicity to neurons by Zou, Jian, Wang, Yan-Xia, Dou, Fang-Fang, Lü, He-Zuo, Ma, Zheng-Wen, Lu, Pei-Hua, Xu, Xiao-Ming

“…Although the role of astrocyte glutamate transporters in glutamate clearance is well illustrated, the role of glutamine synthetase (GS) that influences this…”
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SRPK2 promotes the growth and migration of the colon cancer cells by Wang, Jian, Wu, Hai-Feng, Shen, Wei, Xu, Dong-Yan, Ruan, Ting-Yan, Tao, Guo-Qing, Lu, Pei-hua

“…Colon cancer is one of the major causes of cancer-related death in the world. Understanding the molecular mechanism underlying this malignancy will facilitate…”
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A novel role of phospholipase A2 in mediating spinal cord secondary injury by Liu, Nai-Kui, Zhang, Yi Ping, Titsworth, William Lee, Jiang, Xiaoyan, Han, Shu, Lu, Pei-Hua, Shields, Christopher B., Xu, Xiao-Ming

“…Objective To investigate whether phospholipase A2 (PLA2) plays a role in the pathogenesis of spinal cord injury (SCI). Methods Biochemical, Western blot,…”
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Activation of AMP-activated protein kinase is involved in vincristine-induced cell apoptosis in B16 melanoma cell by Chen, Min-Bin, Shen, Wen-Xiang, Yang, Yun, Wu, Xiao-Yang, Gu, Jin-Hua, Lu, Pei-Hua

“…The molecular basis for induction of apoptosis in melanoma cells by vincristine remains unknown. Here we tested the potential involvement of AMP‐activated…”
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AKR1C1 connects autophagy and oxidative stress by interacting with SQSTM1 in a catalytic-independent manner by Chang, Lin-lin, Li, Yue-kang, Zhao, Chen-xi, Zeng, Chen-ming, Ge, Fu-jing, Du, Jia-min, Zhang, Wen-zhou, Lu, Pei-hua, He, Qiao-jun, Zhu, Hong, Yang, Bo

“…Targeting autophagy might be a promising anticancer strategy; however, the dual roles of autophagy in cancer development and malignancy remain unclear. NSCLC…”
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Dissecting the Conformational Dynamics of the Bile Acid Transporter Homologue ASBTNM by Lu, Pei-Hua, Li, Chieh-Chin, Chiang, Yun-Wei, Liu, Jyung-Hurng, Chiang, Wesley Tien, Chao, Yi-Hsuan, Li, Guan-Syun, Weng, Shao-En, Lin, Sung-Yao, Hu, Nien-Jen

“…[Display omitted] •The mechanism of conformational isomerization of ASBTNM remains undefined.•Na+ binding to ASBTNM does not favor an outward-facing…”
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AKR1C1 promotes non-small cell lung cancer proliferation via crosstalk between HIF-1α and metabolic reprogramming by Chang, Lin-Lin, Lu, Pei-Hua, Yang, Wei, Hu, Yan, Zheng, Lin, Zhao, Qiong, Lin, Neng-Ming, Zhang, Wen-Zhou

“…•AKR1C1 accelerates the proliferation of NSCLC cells.•AKR1C1 remodels metabolism in NSCLC cells.•HIF-1α may play a vital role in AKR1C1-mediated metabolic…”
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Perifosine sensitizes curcumin-induced anti-colorectal cancer effects by targeting multiple signaling pathways both in vivo and in vitro by Chen, Min-Bin, Wu, Xiao-Yang, Tao, Guo-Qing, Liu, Chao-Ying, Chen, Jian, Wang, Li-Qiang, Lu, Pei-Hua

“…Our study shows that coadministration of curcumin and an orally bioactive alkylphospholipid perifosine results in a significant increase in colorectal cancer…”
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KU-0060648 inhibits hepatocellular carcinoma cells through DNA-PKcs-dependent and DNA-PKcs-independent mechanisms by Chen, Min-Bin, Zhou, Zhen-Tao, Yang, Lan, Wei, Mu-Xin, Tang, Min, Ruan, Ting-Yan, Xu, Jun-Ying, Zhou, Xiao-Zhong, Chen, Gang, Lu, Pei-Hua

“…Here we tested anti-tumor activity of KU-0060648 in preclinical hepatocellular carcinoma (HCC) models. Our results demonstrated that KU-0060648 was…”
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Inhibition of cPLA₂ activation by Ginkgo biloba extract protects spinal cord neurons from glutamate excitotoxicity and oxidative stress-induced cell death by Zhao, Zhen, Liu, Naikui, Huang, Jingya, Lu, Pei-Hua, Xu, Xiao-Ming

“…J. Neurochem. (2011) 116, 1057-1065. ABSTRACT: Ginkgo biloba extract (EGb761) has been shown to be neuroprotective; however, the mechanism by which EGb761…”
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Molecular mechanism of panaxydol on promoting axonal growth in PC12 cells by Li, Wei-Peng, Ma, Ke, Jiang, Xiao-Yan, Yang, Rui, Lu, Pei-Hua, Nie, Bao-Ming, Lu, Yang

“…Nerve growth factor (NGF) promotes axonal growth in PC12 cells primarily by regulating the RTK-RAS-MEK-ERK pathway. Panaxydol, a polyacetylene isolated from…”
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