Search Results - "Lu, Liaoxun"

Characterization and comparative analysis of small RNAs in three small RNA libraries of the brown planthopper (Nilaparvata lugens) by Chen, Qiuhong, Lu, Lin, Hua, Hongxia, Zhou, Fei, Lu, Liaoxun, Lin, Yongjun

“…The brown planthopper (BPH), Nilaparvata lugens (Stå;l), which belongs to Homopteran, Delphacidae, is one of the most serious and destructive pests of rice…”
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Pathology and molecular mechanisms of Schistosoma japonicum-associated liver fibrosis by Liu, Zhilong, Zhang, Lichen, Liang, Yinming, Lu, Liaoxun

“…Schistosomiasis has been widely disseminated around the world, and poses a significant threat to human health. Schistosoma eggs and soluble egg antigen (SEA)…”
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Quantitative interactomics in primary T cells unveils TCR signal diversification extent and dynamics by Voisinne, Guillaume, Kersse, Kristof, Chaoui, Karima, Lu, Liaoxun, Chaix, Julie, Zhang, Lichen, Goncalves Menoita, Marisa, Girard, Laura, Ounoughene, Youcef, Wang, Hui, Burlet-Schiltz, Odile, Luche, Hervé, Fiore, Frédéric, Malissen, Marie, Gonzalez de Peredo, Anne, Liang, Yinming, Roncagalli, Romain, Malissen, Bernard

“…The activation of T cells by the T cell antigen receptor (TCR) results in the formation of signaling protein complexes (signalosomes), the composition of which…”
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Excessive immunosuppression by regulatory T cells antagonizes T cell response to schistosome infection in PD-1-deficient mice by Lu, Liaoxun, Li, Tianhan, Feng, Xinyu, Liu, Zhilong, Liu, Yang, Chao, Tianzhu, Gu, Yanrong, Huang, Rong, Zhang, Fanghui, He, Le, Zhou, Binhui, Kong, Eryan, Liu, Zhuangzhuang, Wang, Xugang, Chen, Zhijun, Wang, Hui, Malissen, Marie, Malissen, Bernard, Zhang, Lichen, Liang, Yinming

“…Schistosomiasis is caused by parasitic flatworms known as schistosomes and affects over 200 million people worldwide. Prevention of T cell exhaustion by…”
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Functional analysis of OsPGIP1 in rice sheath blight resistance by Wang, Rui, Lu, Liaoxun, Pan, Xuebiao, Hu, Zongliang, Ling, Fei, Yan, Yan, Liu, Yemao, Lin, Yongjun

“…As one of the most devastating diseases of rice, sheath blight causes severe rice yield loss. However, little progress has been made in rice breeding for…”
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The three members of the Vav family proteins form complexes that concur to foam cell formation and atherosclerosis by Huang, Rong, Guo, Guo, Lu, Liaoxun, Fu, Rui, Luo, Jing, Liu, Zhuangzhuang, Gu, Yanrong, Yang, Wenyi, Zheng, Qianqian, Chao, Tianzhu, He, Le, Wang, Ying, Niu, Zhiguo, Wang, Hui, Lawrence, Toby, Malissen, Marie, Malissen, Bernard, Liang, Yinming, Zhang, Lichen

“…During foam cell formation and atherosclerosis development, the scavenger receptor CD36 plays critical roles in lipid uptake and triggering of atherogenicity…”
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Both JNK1 and JNK2 Are Indispensable for Sensitized Extracellular Matrix Mineralization in IKKβ-Deficient Osteoblasts by Hao, Qianyun, Liu, Zhuangzhuang, Lu, Liaoxun, Zhang, Lichen, Zuo, Li

“…Extracellular matrix mineralization is critical for osteogenesis, and its dysregulation could result in osteoporosis and vascular calcification. IKK/NF-κB…”
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Zdhhc2 Is Essential for Plasmacytoid Dendritic Cells Mediated Inflammatory Response in Psoriasis by Zhou, Binhui, Yang, Wenyi, Li, Wushan, He, Le, Lu, Liaoxun, Zhang, Lichen, Liu, Zhuangzhuang, Wang, Ying, Chao, Tianzhu, Huang, Rong, Gu, Yanrong, Jia, Tingting, Liu, Qiaoli, Tian, Shuanghua, Pierre, Philippe, Maeda, Takahiro, Liang, Yinming, Kong, Eryan

“…Zdhhc family genes are composed of 24 members that regulate palmitoylation, a post-translational modification process for proteins. Mutations in genes that…”
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An inducible model for specific neutrophil depletion by diphtheria toxin in mice by Chao, Tianzhu, Lu, Liaoxun, Zhang, Lichen, Huang, Rong, Liu, Zhuangzhuang, Zhou, Binhui, Kong, Eryan, Zhang, Zhongjian, Lawrence, Toby, Liang, Yinming

“…Neutrophils are crucial for immunity and play important roles in inflammatory diseases; however, mouse models selectively deficient in neutrophils are limited,…”
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A Murine Point Mutation of Sgpl1 Skin Is Enriched With Vγ6 IL17-Producing Cell and Revealed With Hyperpigmentation After Imiquimod Treatment by Yang, Wenyi, Zhou, Binhui, Liu, Qi, Liu, Taozhen, Wang, Huijie, Zhang, Pei, Lu, Liaoxun, Zhang, Lichen, Zhang, Fanghui, Huang, Rong, Zhou, Jitong, Chao, Tianzhu, Gu, Yanrong, Lee, Songhua, Wang, Hui, Liang, Yinming, He, Le

“…Sphingosine-1-phosphate lyase is encoded by the Sgpl1 gene, degrades S1P, and is crucial for S1P homeostasis in animal models and humans. S1P lyase deficient…”
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A severe atherosclerosis mouse model on the resistant NOD background by Wang, Xugang, Huang, Rong, Zhang, Lichen, Li, Saichao, Luo, Jing, Gu, Yanrong, Chen, Zhijun, Zheng, Qianqian, Chao, Tianzhu, Zheng, Wenping, Qi, Xinhui, Wang, Li, Wen, Yinhang, Liang, Yinming, Lu, Liaoxun

“…Atherosclerosis is a complex disease affecting arterial blood vessels and blood flow that could result in a variety of life-threatening consequences. Disease…”
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Loss of natural resistance to schistosome in T cell deficient rat by Lu, Liaoxun, Hu, Junjian, Chao, Tianzhu, Chen, Zhijun, Liu, Zhuangzhuang, Luo, Xinsong, Liang, Yinming, He, Pei, Zhang, Lichen

“…Schistosomiasis is among the major neglected tropical diseases and effective prevention by boosting the immune system is still not available. T cells are key…”
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Dedicator of cytokinesis 8 (DOCK8) mutation impairs the differentiation of helper T cells by regulating the glycolytic pathway of CD4+ T cells by Jiang, Panpan, Zhao, Siyu, Li, Xiaoyu, Hu, Shiyan, Chen, Shuhan, Liang, Yinming, Zhang, Lichen, Lu, Liaoxun, Fang, Guofeng, Yang, Lu, Huang, Yanmei, Miller, Heather, Guan, Fei, Lei, Jiahui, Liu, Chaohong

“…Dedicator of cytokinesis 8 (DOCK8) deficiency is a primary immunodeficiency disease caused by mutations in exon 45 of the DOCK8 gene. The clinical signs…”
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Precise and Rapid Validation of Candidate Gene by Allele Specific Knockout With CRISPR/Cas9 in Wild Mice by Chao, Tianzhu, Liu, Zhuangzhuang, Zhang, Yu, Zhang, Lichen, Huang, Rong, He, Le, Gu, Yanrong, Chen, Zhijun, Zheng, Qianqian, Shi, Lijin, Zheng, Wenping, Qi, Xinhui, Kong, Eryan, Zhang, Zhongjian, Lawrence, Toby, Liang, Yinming, Lu, Liaoxun

“…It is a tempting goal to identify causative genes underlying phenotypic differences among inbred strains of mice, which is a huge reservoir of genetic…”
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sgRNA Knock-in Mouse Provides an Alternative Approach for In Vivo Genetic Modification by Zhang, Lichen, Li, Wushan, Liu, Zhuangzhuang, Liu, Yang, Liu, Zhilong, Gu, Yanrong, He, Le, Zhou, Binhui, Li, Tianhan, Chao, Tianzhu, Liang, Yinming, Lu, Liaoxun

“…Functional genomics in a mammalian model such as mice is fundamental for understanding human biology. The CRISPR/Cas9 system dramatically changed the tempo of…”
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Expression profile analysis of the polygalacturonase-inhibiting protein genes in rice and their responses to phytohormones and fungal infection by Lu, Liaoxun, Zhou, Fei, Zhou, Yong, Fan, Xiaolei, Ye, Shuifeng, Wang, Lei, Chen, Hao, Lin, Yongjun

“…Polygalacturonase-inhibiting proteins (PGIPs) are typically leucine-rich repeat (LRR) proteins that can inhibit the activity of fungal polygalacturonases…”
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Identification of quantitative trait loci controlling rice mature seed culturability using chromosomal segment substitution lines by Zhao, Lina, Zhou, Hongju, Lu, Liaoxun, Liu, Li, Li, Xianghua, Lin, Yongjun, Yu, Sibin

“…The genetic transformation efficiency of a rice variety is largely determined by its tissue culturability. Establishment of a highly efficient tissue-culture…”
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Slfn4 deficiency improves MAPK-mediated inflammation, oxidative stress, apoptosis and abates atherosclerosis progression in apolipoprotein E-deficient mice by Zheng, Qianqian, Duan, Liangwei, Lou, Yunwei, Chao, Tianzhu, Guo, Guo, Lu, Liaoxun, Zhang, Hongxia, Zhao, Yucong, Liang, Yinming, Wang, Hui

“…Atherosclerosis, a progressive inflammatory disease characterized by elevated inflammation and lipid accumulation in the aortic endothelium, arises in part…”
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GFAP hyperpalmitoylation exacerbates astrogliosis and neurodegenerative pathology in PPT1-deficient mice by Yuan, Wei, Lu, Liaoxun, Rao, Muding, Huang, Yang, Liu, Chun-e, Liu, Shuang, Zhao, Yue, Liu, Huicong, Zhu, Jiangli, Chao, Tianzhu, Wu, Can, Ren, Junyan, Lv, Luxian, Li, Wenqiang, Qi, Shiqian, Liang, Yinming, Yue, Shijing, Gao, Jian, Zhang, Zhongjian, Kong, Eryan

“…The homeostasis of protein palmitoylation and depalmitoylation is essential for proper physiological functions in various tissues, in particular the central…”
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Distinct palmitoylation of Foxp3 regulates the function of regulatory T cells via palmitoyltransferases by Zhou, Binhui, Zhang, Mengjie, Ma, Haoyuan, Wang, Ying, Qiu, Juanjuan, Liu, Yang, Lu, Liaoxun, Li, Tianhan, Zhang, Lichen, Huang, Rong, Gu, Yanrong, Kong, Eryan, Liang, Yinming

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