Search Results - "Lu, Ku"

Systemic pan-AMPK activator MK-8722 improves glucose homeostasis but induces cardiac hypertrophy by Myers, Robert W., Guan, Hong-Ping, Ehrhart, Juliann, Petrov, Aleksandr, Prahalada, Srinivasa, Tozzo, Effie, Yang, Xiaodong, Kurtz, Marc M., Trujillo, Maria, Trotter, Dinko Gonzalez, Feng, Danqing, Xu, Shiyao, Eiermann, George, Holahan, Marie A., Rubins, Daniel, Conarello, Stacey, Niu, Xiaoda, Souza, Sandra C., Miller, Corin, Liu, Jinqi, Lu, Ku, Feng, Wen, Li, Ying, Painter, Ronald E., Milligan, James A., He, Huaibing, Liu, Franklin, Ogawa, Aimie, Wisniewski, Douglas, Rohm, Rory J., Wang, Liyang, Bunzel, Michelle, Qian, Ying, Zhu, Wei, Wang, Hongwu, Bennet, Bindu, Scheuch, Lisa LaFranco, Fernandez, Guillermo E., Li, Cai, Klimas, Michael, Zhou, Gaochao, van Heek, Margaret, Biftu, Tesfaye, Weber, Ann, Kelley, David E., Thornberry, Nancy, Erion, Mark D., Kemp, Daniel M., Sebhat, Iyassu K.

“…5′-Adenosine monophosphate–activated protein kinase (AMPK) is a master regulator of energy homeostasis in eukaryotes. Despite three decades of investigation,…”
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Ketohexokinase knockout mice, a model for essential fructosuria, exhibit altered fructose metabolism and are protected from diet-induced metabolic defects by Miller, Corin O, Yang, Xiaodong, Lu, Ku, Cao, Jin, Herath, Kithsiri, Rosahl, Thomas W, Askew, Roger, Pavlovic, Guillaume, Zhou, Gaochao, Li, Cai, Akiyama, Taro E

“…Fructose consumption in humans and animals has been linked to enhanced de novo lipogenesis, dyslipidemia, and insulin resistance. Hereditary deficiency of…”
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Glucagon receptor antagonism induces increased cholesterol absorption[S] by Guan, Hong-Ping, Yang, Xiaodong, Lu, Ku, Wang, Sheng-Ping, Castro-Perez, Jose M., Previs, Stephen, Wright, Michael, Shah, Vinit, Herath, Kithsiri, Xie, Dan, Szeto, Daphne, Forrest, Gail, Xiao, Jing Chen, Palyha, Oksana, Sun, Li-Ping, Andryuk, Paula J., Engel, Samuel S., Xiong, Yusheng, Lin, Songnian, Kelley, David E., Erion, Mark D., Davis, Harry R., Wang, Liangsu

“…Glucagon and insulin have opposing action in governing glucose homeostasis. In type 2 diabetes mellitus (T2DM), plasma glucagon is characteristically elevated,…”
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Pharmacological AMPK activation induces transcriptional responses congruent to exercise in skeletal and cardiac muscle, adipose tissues and liver by Muise, Eric S, Guan, Hong-Ping, Liu, Jinqi, Nawrocki, Andrea R, Yang, Xiaodong, Wang, Chuanlin, Rodríguez, Carlos G, Zhou, Dan, Gorski, Judith N, Kurtz, Marc M, Feng, Danqing, Leavitt, Kenneth J, Wei, Lan, Wilkening, Robert R, Apgar, James M, Xu, Shiyao, Lu, Ku, Feng, Wen, Li, Ying, He, Huaibing, Previs, Stephen F, Shen, Xiaolan, van Heek, Margaret, Souza, Sandra C, Rosenbach, Mark J, Biftu, Tesfaye, Erion, Mark D, Kelley, David E, Kemp, Daniel M, Myers, Robert W, Sebhat, Iyassu K

“…Physical activity promotes metabolic and cardiovascular health benefits that derive in part from the transcriptional responses to exercise that occur within…”
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Physiological Expression of AMPKγ2 Mutation Causes Wolff-Parkinson-White Syndrome and Induces Kidney Injury in Mice by Yang, Xiaodong, Mudgett, John, Bou-About, Ghina, Champy, Marie-France, Jacobs, Hugues, Monassier, Laurent, Pavlovic, Guillaume, Sorg, Tania, Herault, Yann, Petit-Demoulière, Benoit, Lu, Ku, Feng, Wen, Wang, Hongwu, Ma, Li-Jun, Askew, Roger, Erion, Mark D., Kelley, David E., Myers, Robert W., Li, Cai, Guan, Hong-Ping

“…Mutations of the AMP-activated kinase gamma 2 subunit (AMPKγ2), N488I (AMPKγ2NI) and R531G (AMPKγ2RG), are associated with Wolff-Parkinson-White (WPW)…”
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Discovery of MK-8722: A Systemic, Direct Pan-Activator of AMP-Activated Protein Kinase by Feng, Danqing, Biftu, Tesfaye, Romero, F. Anthony, Kekec, Ahmet, Dropinski, James, Kassick, Andrew, Xu, Shiyao, Kurtz, Marc M, Gollapudi, Anantha, Shao, Qing, Yang, Xiaodong, Lu, Ku, Zhou, Gaochao, Kemp, Daniel, Myers, Robert W, Guan, Hong-Ping, Trujillo, Maria E, Li, Cai, Weber, Ann, Sebhat, Iyassu K

“…5′-Adenosine monophosphate-activated protein kinase (AMPK) is a key regulator of mammalian energy homeostasis and has been implicated in mediating many of the…”
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Blue light negatively regulates the sexual filamentation via the Cwc1 and Cwc2 proteins in Cryptococcus neoformans by Lu, Ying‐Ku, Sun, Kai‐Hui, Shen, Wei‐Chiang

“…Summary Cryptococcus neoformans is a heterothallic basidiomycetous yeast that primarily infects immunocompromised individuals. Dikaryotic hyphae resulting from…”
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Shock Tube Study on the Thermal Decomposition of CH3OH by Lu, Ku-We, Matsui, Hiroyuki, Huang, Ching-Liang, Raghunath, P, Wang, Niann-Shiah, Lin, M. C

“…H atom produced in the thermal decomposition of CH3OH highly diluted in Ar (0.48−10 ppm) was monitored behind reflected shock waves by atomic resonance…”
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Nonlinearity analysis of R-2R ladder-based current-steering digital to analog converter by Chun-Chieh Chen, Nan-Ku Lu

“…This paper presents a theoretical nonlinearity analysis of R-2R ladder-based current-steering digital to analog converter (DAC). Besides the current…”
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The subcellular localization and protein stability of mouse alpha-actinin 2 is controlled by its nuclear receptor binding motif in C2C12 cells by Lin, Wei-Shiang, Lu, Ku-Mu, Chung, Min-Huey, Liu, Shu-Ting, Chen, Huan-Hsin, Chang, Yung-Lung, Wang, Wei-Ming, Huang, Shih-Ming

“…Alpha actinin (ACTN) has emerged as a multitasking protein, whose roles range from bundling actin filaments to functioning as a versatile protein interaction…”
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Improving rubber concrete by waste organic sulfur compounds by Chou, Liang-Hisng, Lin, Chun-Nan, Lu, Chun-Ku, Lee, Cheng-Haw, Lee, Maw-Tien

“…In this study, the use of crumb tyres as additives to concrete was investigated. For some time, researchers have been studying the physical properties of…”
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Use of waste rubber as concrete additive by Chou, Liang Hsing, Lu, Chun-Ku, Chang, Jen-Ray, Lee, Maw Tien

“…For resource reutilization, scrap tyres have long been investigated as an additive to concrete to form ‘Rubcrete’ for various applications and have shown…”
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Cryptophycin-induced hyperphosphorylation of Bcl-2, cell cycle arrest and growth inhibition in human H460 NSCLC cells by KU LU, DEMPSEY, Jack, SCHULTZ, Richard M, SHIH, Chuan, TEICHER, Beverly A

“…Bcl-2 has been described as a factor that can protect from apoptosis. The protective effect of Bcl-2 may be lost if the protein is phosphorylated. Bcl-2…”
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Dihydropyrrolopyrazole Transforming Growth Factor-β Type I Receptor Kinase Domain Inhibitors:  A Novel Benzimidazole Series with Selectivity versus Transforming Growth Factor-β Type II Receptor Kinase and Mixed Lineage Kinase-7 by Li, Hong-yu, Wang, Yan, Heap, Charles R, King, Chi-Hsin R, Mundla, Sreenivasa R, Voss, Matthew, Clawson, David K, Yan, Lei, Campbell, Robert M, Anderson, Bryan D, Wagner, Jill R, Britt, Karen, Lu, Ku X, McMillen, William T, Yingling, Jonathan M

“…Novel dihydropyrrolopyrazole-substituted benzimidazoles were synthesized and evaluated in vitro as inhibitors of transforming growth factor-β type I receptor…”
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Nonlinearity analysis of double multi-bit decided folded resistor string digital-to-analog converter by Chen, Chun-Chieh, Lu, Nan-Ku, Zeng, Yi-Zhi

“…This paper presents a double multi-bit decided folded resistor string digital-to-analog converter that notably reduces the number of output voltage nodes…”
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Study on ripple effect of ferromagnetic WCCB blanket modules in CFETR by Lei, Mingzhun, Lu, Kun, Song, Yuntao, Zhang, Shanwen, Wang, Ming, Xu, Shuling, Xu, Kun, Liu, Songlin

“…•Investigate and evaluate the ripple effect of WCCB blanket on TF ripple in CFETR.•CFETR TF ripple generated by WCCB blanket has been calculated.•Potential…”
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Abstract 524: The novel STING agonist VB-85247 induces robust durable antitumor immune responses by intravesical administration in a non-muscle invasive bladder cancer model by Prabagar, Miglena, Bommireddy, Venu, Siegel, Rachael, Zheng, Haihua, Pellegrino, Lee, Nawoschik, Stanley, Uveges, Albert, Paget, Steven, Lu, Ku, Saufler, Krista, Metzger, Axel, Diller, David, Trama, Jason, Gallagher, Grant, Huang, Chia-Yu, McGuinness, Brian, Beasley, James R., McQueney, Michael, Adelson, Martin, Schieven, Gary L., Mordechai, Eli, Eraslan, Rukiye-Nazan

“…Abstract Introduction: Bacillus Calmette-Guerin (BCG) unresponsive non-muscle invasive bladder cancer (NMIBC) patients are in great need of effective…”
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Nonlinearity analysis of folded Multi-LSB decided resistor string digital to analog converter by Chen, Chun-Chieh, Lu, Nan-Ku, Zeng, Yi-Zhi

“…A theoretical nonlinearity analysis of folded multi-LSB decided resistor string DAC is presented. By the derived theoretical equations, circuit designers can…”
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Low gain error, linear-in-dB variable gain amplifier with programmable gain range and gain steps by Chen, Chun-Chieh, Lu, Nan-Ku, Zeng, Yi-Zhi

“…This paper presents a linear-in-dB variable gain amplifier (VGA) with programmable gain range and gain step, and low gain error. A 4-bit digitally controlled…”
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Physiological Expression of AMPKγ2RG Mutation Causes Wolff-Parkinson-White Syndrome and Induces Kidney Injury in Mice by Yang, Xiaodong, Mudgett, John, Bou-About, Ghina, Champy, Marie-France, Jacobs, Hugues, Monassier, Laurent, Pavlovic, Guillaume, Sorg, Tania, Herault, Yann, Petit-Demoulière, Benoit, Lu, Ku, Feng, Wen, Wang, Hongwu, Ma, Li-Jun, Askew, Roger, Erion, Mark D., Kelley, David E., Myers, Robert W., Li, Cai, Guan, Hong-Ping

“…Mutations of the AMP-activated kinase gamma 2 subunit (AMPKγ2), N488I (AMPKγ2NI) and R531G (AMPKγ2RG), are associated with Wolff-Parkinson-White (WPW)…”
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