Search Results - "Lu, Jibu"

Development and Verification of a Prognostic Ferroptosis-Related Gene Model in Triple-Negative Breast Cancer by Wu, Song, Pan, Ruilin, Lu, Jibu, Wu, Xiaoling, Xie, Jingdong, Tang, Hailin, Li, Xing

“…Triple-negative breast cancer (TNBC) is the subtype with the worst prognosis of breast cancer. Ferroptosis, a novel iron-dependent programmed cell death, has…”
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A novel axis of circKIF4A-miR-637-STAT3 promotes brain metastasis in triple-negative breast cancer by Wu, Song, Lu, Jibu, Zhu, Hongbo, Wu, Feiyue, Mo, Yunxian, Xie, Liming, Song, Cailu, Liu, Lingrui, Xie, Xiaoming, Li, Yuehua, lin, Huan, Tang, Hailin

“…Among patients with triple-negative breast cancer (TNBC), distant metastasis is the leading cause of death. Our previous studies have shown that TNBC…”
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Discovery of the First Examples of Threonine Tyrosine Kinase PROTAC Degraders by Lu, Jibu, Huang, Yongjun, Huang, Jing, He, Rui, Huang, Minhao, Lu, Xiaoyun, Xu, Yong, Zhou, Fengtao, Zhang, Zhang, Ding, Ke

“…The first examples of threonine tyrosine kinase (TTK) PROTACs were designed and synthesized. Two of the most potent molecules, 8e and 8j, demonstrated strong…”
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Structure-Based Discovery and Optimization of Furo[3,2‑c]pyridin-4(5H)‑one Derivatives as Potent and Second Bromodomain (BD2)-Selective Bromo and Extra Terminal Domain (BET) Inhibitors by Li, Junhua, Zhang, Cheng, Xu, Hongrui, Wang, Chao, Dong, Ruibo, Shen, Hui, Zhuang, Xiaoxi, Chen, Xiaoshan, Li, Qiu, Lu, Jibu, Zhang, Maofeng, Wu, Xishan, Loomes, Kerry M, Zhou, Yulai, Zhang, Yan, Liu, Jinsong, Xu, Yong

“…Pan-bromodomain and extra terminal (Pan-BET) inhibitors show profound efficacy but exhibit pharmacology-driven toxicities in clinical trials. The development…”
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Identification and Optimization of New Dual Inhibitors of B‑Raf and Epidermal Growth Factor Receptor Kinases for Overcoming Resistance against Vemurafenib by Cheng, Huimin, Chang, Yu, Zhang, Lianwen, Luo, Jinfeng, Tu, Zhengchao, Lu, Xiaoyun, Zhang, Qingwen, Lu, Jibu, Ren, Xiaomei, Ding, Ke

“…Epidermal growth factor receptor (EGFR) amplification has been demonstrated to be critical for the inherent and/or acquired resistance against current…”
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