Search Results - "Lu, Hanxin"

A Randomized, Blinded, Controlled, Dose-Ranging Study of a Respiratory Syncytial Virus Recombinant Fusion (F) Nanoparticle Vaccine in Healthy Women of Childbearing Age by Glenn, Gregory M., Fries, Louis F., Thomas, D. Nigel, Smith, Gale, Kpamegan, Eloi, Lu, Hanxin, Flyer, David, Jani, Dewal, Hickman, Somia P., Piedra, Pedro A.

“…Background. Respiratory syncytial virus (RSV) is a leading cause of infant morbidity and mortality. A recombinant RSV fusion protein nanoparticle vaccine (RSV…”
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Respiratory syncytial virus fusion glycoprotein expressed in insect cells form protein nanoparticles that induce protective immunity in cotton rats by Smith, Gale, Raghunandan, Rama, Wu, Yingyun, Liu, Ye, Massare, Michael, Nathan, Margret, Zhou, Bin, Lu, Hanxin, Boddapati, Sarathi, Li, Jingning, Flyer, David, Glenn, Gregory

“…Respiratory Syncytial Virus (RSV) is an important viral agent causing severe respiratory tract disease in infants and children as well as in the elderly and…”
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VXX-401, a novel anti-PCSK9 vaccine, reduces LDL-C in cynomolgus monkeys by Vroom, Madeline M., Lu, Hanxin, Lewis, Maggie, Thibodeaux, Brett A., Brooks, Jeanne K., Longo, Matthew S., Ramos, Martina M., Sahni, Jaya, Wiggins, Jonathan, Boyd, Justin D., Wang, Shixia, Ding, Shuang, Hellerstein, Michael, Ryan, Valorie, Powchik, Peter, Dodart, Jean-Cosme

“…Atherosclerotic cardiovascular disease (ASCVD) remains the leading cause of disease burden in the world and is highly correlated with chronic elevations of…”
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Safety and immunogenicity of a Sf9 insect cell-derived respiratory syncytial virus fusion protein nanoparticle vaccine by Glenn, Gregory M, Smith, Gale, Fries, Louis, Raghunandan, Rama, Lu, Hanxin, Zhou, Bin, Thomas, D. Nigel, Hickman, Somia P, Kpamegan, Eloi, Boddapati, Sarathi, Piedra, Pedro A

“…Highlights ► This Phase 1 trial evaluated the safety and immunogenicity of an RSV (F) nanoparticle vaccine. ► The vaccine was well-tolerated and no related…”
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An insect cell derived respiratory syncytial virus (RSV) F nanoparticle vaccine induces antigenic site II antibodies and protects against RSV challenge in cotton rats by active and passive immunization by Raghunandan, Rama, Lu, Hanxin, Zhou, Bin, Xabier, Mimi Guebre, Massare, Michael J, Flyer, David C, Fries, Louis F, Smith, Gale E, Glenn, Gregory M

“…Highlights • RSV F nanoparticle vaccine induced palivizumab competing antibodies (PCA). • PCA is in excess of serum protective levels than IM injected…”
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Immunogenicity and safety of a respiratory syncytial virus fusion protein (RSV F) nanoparticle vaccine in older adults by Fries, Louis, Shinde, Vivek, Stoddard, Jeffrey J, Thomas, D Nigel, Kpamegan, Eloi, Lu, Hanxin, Smith, Gale, Hickman, Somia P, Piedra, Pedro, Glenn, Gregory M

“…A preventative strategy for Respiratory Syncytial Virus (RSV) infection constitutes an under-recognized unmet medical need among older adults. Four…”
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Structure basis of neutralization by a novel site II/IV antibody against respiratory syncytial virus fusion protein by Xie, Qingqing, Wang, Zhao, Ni, Fengyun, Chen, Xiaorui, Ma, Jianpeng, Patel, Nita, Lu, Hanxin, Liu, Ye, Tian, Jing-Hui, Flyer, David, Massare, Michael J, Ellingsworth, Larry, Glenn, Gregory, Smith, Gale, Wang, Qinghua

“…Globally, human respiratory syncytial virus (RSV) is a leading cause of lower respiratory tract infections in newborns, young children, and the elderly for…”
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HDAC1 Acetylation Is Linked to Progressive Modulation of Steroid Receptor-Induced Gene Transcription by Qiu, Yi, Zhao, Yingming, Becker, Matthias, John, Sam, Parekh, Bhavin S., Huang, Suming, Hendarwanto, Anindya, Martinez, Elisabeth D., Chen, Yue, Lu, Hanxin, Adkins, Nicholas L., Stavreva, Diana A., Wiench, Malgorzata, Georgel, Philippe T., Schiltz, R. Louis, Hager, Gordon L.

“…Although histone deacetylases (HDACs) are generally viewed as corepressors, we show that HDAC1 serves as a coactivator for the glucocorticoid receptor (GR)…”
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A rapid Flp-In system for expression of secreted H5N1 influenza hemagglutinin vaccine immunogen in mammalian cells by Lu, Hanxin, Khurana, Surender, Verma, Nitin, Manischewitz, Jody, King, Lisa, Beigel, John H, Golding, Hana

“…Continuing transmissions of highly pathogenic H5N1 viruses in poultry and humans underscores the need for a rapid response to potential pandemic in the form of…”
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Tax Interacts with P-TEFb in a Novel Manner To Stimulate Human T-Lymphotropic Virus Type 1 Transcription by MEISHENG ZHOU, HANXIN LU, PARK, Hyeon, WILSON-CHIRU, Jaime, LINTON, Rebecca, BRADY, John N

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Novel Functions for TAF7, a Regulator of TAF1-independent Transcription by Devaiah, Ballachanda N., Lu, Hanxin, Gegonne, Anne, Sercan, Zeynep, Zhang, Hongen, Clifford, Robert J., Lee, Maxwell P., Singer, Dinah S.

“…The transcription factor TFIID components TAF7 and TAF1 regulate eukaryotic transcription initiation. TAF7 regulates transcription initiation of TAF1-dependent…”
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TFIID component TAF7 functionally interacts with both TFIIH and P-TEFb by Gegonne, Anne, Weissman, Jocelyn D, Lu, Hanxin, Zhou, Meisheng, Dasgupta, Arindam, Ribble, Robert, Brady, John N, Singer, Dinah S

“…Transcription consists of a series of highly regulated steps: assembly of the preinitiation complex (PIC) at the promoter, initiation, elongation, and…”
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PCAF Interacts with Tax and Stimulates Tax Transactivation in a Histone Acetyltransferase-Independent Manner by Jiang, Hua, Lu, Hanxin, Schiltz, R. Louis, Pise-Masison, Cynthia A., Ogryzko, Vasily V., Nakatani, Yoshihiro, Brady, John N.

“…ERRATUM ( vol. 20 , p. 1897 ) Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious…”
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Coactivator-Associated Arginine Methyltransferase 1 Enhances Transcriptional Activity of the Human T-Cell Lymphotropic Virus Type 1 Long Terminal Repeat through Direct Interaction with Tax by JEONG, Soo-Jin, HANXIN LU, CHO, Won-Kyung, HYEON UNG PARK, PISE-MASISON, Cynthia, BRADY, John N

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Tax Relieves Transcriptional Repression by Promoting Histone Deacetylase 1 Release from the Human T-Cell Leukemia Virus Type 1 Long Terminal Repeat by Lu, H, Pise-Masison, CA, Linton, R, Park, HU, Schiltz, R L, Sartorelli, V, Brady, J N

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Acetylation of Nucleosomal Histones by p300 Facilitates Transcription from Tax-Responsive Human T-Cell Leukemia Virus Type 1 Chromatin Template by Lu, Hanxin, Pise-Masison, Cynthia A., Fletcher, Terace M., Schiltz, R. Louis, Nagaich, Akhilesh K., Radonovich, Michael, Hager, Gordon, Cole, Philip A., Brady, John N.

“…AUTHOR'S CORRECTION ( vol. 22 , p. 6930 ) Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike…”
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A Phase 2 randomized, observer-blind, placebo-controlled, dose-ranging trial of aluminum-adjuvanted respiratory syncytial virus F particle vaccine formulations in healthy women of childbearing age by August, Allison, Glenn, Gregory M, Kpamegan, Eloi, Hickman, Somia P, Jani, Dewal, Lu, Hanxin, Thomas, D. Nigel, Wen, Judy, Piedra, Pedro A, Fries, Louis F

“…Abstract Objective Respiratory syncytial virus (RSV) causes significant morbidity and mortality in infants. We are developing an RSV fusion (F) protein…”
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Matrix-M adjuvant enhances antibody, cellular and protective immune responses of a Zaire Ebola/Makona virus glycoprotein (GP) nanoparticle vaccine in mice by Bengtsson, Karin Lövgren, Song, Haifeng, Stertman, Linda, Liu, Ye, Flyer, David C, Massare, Michael J, Xu, Ren-Huan, Zhou, Bin, Lu, Hanxin, Kwilas, Steve A, Hahn, Timothy J, Kpamegan, Eloi, Hooper, Jay, Carrion, Ricardo, Glenn, Gregory, Smith, Gale

“…Highlights • Recombinant Ebola virus glycoprotein nanoparticle vaccine induces B and T cell responses in mice. • Matrix-M adjuvant provides significant immune…”
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Respiratory syncytial virus prefusogenic fusion (F) protein nanoparticle vaccine: Structure, antigenic profile, immunogenicity, and protection by Patel, Nita, Massare, Mike J, Tian, Jing-Hui, Guebre-Xabier, Mimi, Lu, Hanxin, Zhou, Haixia, Maynard, Ernest, Scott, Daniel, Ellingsworth, Larry, Glenn, Gregory, Smith, Gale

“…AbstractRespiratory syncytial virus (RSV) is a major cause of severe respiratory disease in the very young, elderly, and immunocompromised for which there is…”
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VXX-401, AN INVESTIGATIONAL PCSK9 VACCINE FOR THE PREVENTION OF CARDIOVASCULAR DISEASE by Dodart, Jean-Cosme, Boyd, Justin, Chirinos-Rojas, Carlos, Lu, Hanxin, Wang, Shixia, Ding, Shuang, Thibodeaux, Brett, Vroom, Madeline, Sahni, Jaya, Ramos, Martina M., Liu, Zhi, Wang, Lixia, Mohapatra, Nrusingh, Longo, Matthew, Wiggins, Jonathan, Sun, Yushuang

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