Search Results - "Lu, Gaoyuan"

Quantitative Mass Spectrometry Reveals Food Intake-Induced Neuropeptide Level Changes in Rat Brain: Functional Assessment of Selected Neuropeptides as Feeding Regulators by Ye, Hui, Wang, Jingxin, Tian, Zichuan, Ma, Fengfei, Dowell, James, Bremer, Quentin, Lu, Gaoyuan, Baldo, Brian, Li, Lingjun

“…Endogenous neuropeptides are important signaling molecules that function as regulators of food intake and body weight. Previous work has shown that…”
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Spatially and temporally probing distinctive glycerophospholipid alterations in Alzheimer’s disease mouse brain via high-resolution ion mobility-enabled sn-position resolved lipidomics by Xu, Shuling, Zhu, Zhijun, Delafield, Daniel G., Rigby, Michael J., Lu, Gaoyuan, Braun, Megan, Puglielli, Luigi, Li, Lingjun

“…Dysregulated glycerophospholipid (GP) metabolism in the brain is associated with the progression of neurodegenerative diseases including Alzheimer’s disease…”
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Conjugation site analysis of antibody-drug-conjugates (ADCs) by signature ion fingerprinting and normalized area quantitation approach using nano-liquid chromatography coupled to high resolution mass spectrometry by Sang, Hua, Lu, Gaoyuan, Liu, Yazhong, Hu, Qiyue, Xing, Weifeng, Cui, Dongbing, Zhou, Fang, Zhang, Jingwei, Hao, Haiping, Wang, Guangji, Ye, Hui

“…Trastuzumab-MCC-DM1 (T-DM1) is an antibody-drug conjugate (ADC) that consists of a monoclonal antibody (mAb) trastuzumab non-cleavably linked to a cytotoxic…”
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An Atmospheric Turbulence Compensation Algorithm Based on FSM-DM Cascaded AO Architecture for FSO Communications by Mao, Hongliang, Zhong, Jie, Yu, Siyuan, Xiao, Pei, Yang, Xinghao, Lu, Gaoyuan

“…Free-space optics (FSO) communication enjoys desirable modulation rates at unexploited frequency bands, however, its application is hindered by atmospheric…”
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High-end ion mobility mass spectrometry: A current review of analytical capacity in omics applications and structural investigations by Delafield, Daniel G., Lu, Gaoyuan, Kaminsky, Cameron J., Li, Lingjun

“…Mass spectrometry-based biomolecular analyses have become permanent fixtures of academic, industrial, and clinical research settings. The rise in utilization…”
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Neuropeptidomics of the American Lobster Homarus americanus by Lu, Gaoyuan, Tran, Vu Ngoc Huong, Wu, Wenxin, Ma, Min, Li, Lingjun

“…The American lobster, Homarus americanus, is not only of considerable economic importance but has also emerged as a premier model organism in neuroscience…”
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On the correlated Gamma–Gamma distribution and coherent detection performance of optical spatial modulation by Geng, Chi, Yu, Siyuan, Lu, Gaoyuan, Wang, Yiqun

“…The performance of optical spatial modulation (OSM) is severely damaged by correlated atmospheric turbulence (AT) channels for coherent free-space optical…”
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Carbene Footprinting Directs Design of Genetically Encoded Proximity-Reactive Protein Binders by Ye, Hui, Zhu, Yinxue, Kong, Ying, Wen, Hongtao, Lu, Wenjie, Wang, Dexiang, Tang, Shuo, Zhan, Mengru, Lu, Gaoyuan, Shao, Chang, Wang, Nanxi, Hao, Haiping

“…Genetically encoding proximal-reactive unnatural amino acids (PrUaas), such as fluorosulfate-l-tyrosine (FSY), into natural proteins of interest (POI) confer…”
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Satellite platform vibration influence on acquisition system for intersatellite optical communications by Ma, Jing, Lu, Gaoyuan, Tan, Liying, Yu, Siyuan, Fu, Yulong, Li, Fajun

“…•Mathematical models are introduced to redefine the acquisition with vibration in IOLs.•Analytical expression of SLP is derived through newly models for…”
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Global Neuropeptidome Profiling in Response to Predator Stress in Rat: Implications for Post-Traumatic Stress Disorder by Wu, Wenxin, Ma, Min, Ibarra, Angel Erbey, Lu, Gaoyuan, Bakshi, Vaishali P., Li, Lingjun

“…Traumatic stress triggers or exacerbates multiple psychiatric illnesses, including post-traumatic stress disorder (PTSD). Nevertheless, the neurophysiological…”
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CHRISTMAS: Chiral Pair Isobaric Labeling Strategy for Multiplexed Absolute Quantitation of Enantiomeric Amino Acids by Zhu, Zhijun, Xu, Shuling, Wang, Zicong, Delafield, Daniel G., Rigby, Michael J., Lu, Gaoyuan, Gu, Ting-Jia, Liu, Peng-Kai, Ma, Min, Puglielli, Luigi, Li, Lingjun

“…Amino acids (AAs) in the d-form are involved in multiple pivotal neurological processes, although their l-enantiomers are most commonly found. Mass…”
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Metabolomics–Proteomics Combined Approach Identifies Differential Metabolism-Associated Molecular Events between Senescence and Apoptosis by Wu, Mengqiu, Ye, Hui, Shao, Chang, Zheng, Xiao, Li, Qingran, Wang, Lin, Zhao, Min, Lu, Gaoyuan, Chen, Baoqiang, Zhang, Jun, Wang, Yun, Wang, Guangji, Hao, Haiping

“…Apoptosis and senescence are two types of cell fates in response to chemotherapy. Besides canonical pathways that mediate cell fates, cancer cell metabolism…”
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p53 dynamics orchestrates with binding affinity to target genes for cell fate decision by Wu, Mengqiu, Ye, Hui, Tang, Zhiyuan, Shao, Chang, Lu, Gaoyuan, Chen, Baoqiang, Yang, Yuyu, Wang, Guangji, Hao, Haiping

“…Emerging evidence support that temporal dynamics is pivotal for signaling molecules in orchestrating smart responses to diverse stimuli. p53 is such a…”
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Conjugation Site Analysis of Lysine-Conjugated ADCs by Sang, Hua, Wan, Ning, Lu, Gaoyuan, Tian, Yang, Wang, Guangji, Ye, Hui

“…Lysine-conjugated antibody-drug conjugates (ADCs) are formed by attaching cytotoxic drugs to reactive lysine residues of monoclonal antibodies (mAbs) through…”
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Subresidue-Resolution Footprinting of Ligand–Protein Interactions by Carbene Chemistry and Ion Mobility–Mass Spectrometry by Lu, Gaoyuan, Xu, Xiaowei, Li, Gongyu, Sun, Huiyong, Wang, Nian, Zhu, Yinxue, Wan, Ning, Shi, Yatao, Wang, Guangji, Li, Lingjun, Hao, Haiping, Ye, Hui

“…The knowledge of ligand–protein interactions is essential for understanding fundamental biological processes and for the rational design of drugs that target…”
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Pointing errors effect on fiber coupling efficiency for Gaussian-beam wave through atmospheric turbulence channel in FSO links by Lu, Gaoyuan, Ma, Jing, Zhai, Chao, Yu, Siyuan, Tan, Liying, Fu, Yulong, Li, Fajun

“…In this paper, we theoretically study the pointing errors effect on fiber coupling efficiency for Gaussian-beam wave with consideration of atmospheric…”
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Temporal power spectrum of irradiance fluctuations for a Gaussian-beam wave propagating through non-Kolmogorov turbulence by Tan, Liying, Zhai, Chao, Yu, Siyuan, Ma, Jing, Lu, Gaoyuan

“…In the past decades, both the increasing experimental evidence and some results of theoretical investigation on non-Kolmogorov turbulence have been reported…”
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Site-specific chirality-conferred structural compaction differentially mediates the cytotoxicity of Aβ42 by Li, Gongyu, Jeon, Chae Kyung, Ma, Min, Jia, Yifei, Zheng, Zhen, Delafield, Daniel G, Lu, Gaoyuan, Romanova, Elena V, Sweedler, Jonathan V, Ruotolo, Brandon T, Li, Lingjun

“…Growing evidence supports the confident association between distinct amyloid beta (Aβ) isoforms and Alzheimer's Disease (AD) pathogenesis. As such, critical…”
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Integrative Omics Analysis Revealed that Metabolic Intervention Combined with Metronomic Chemotherapy Selectively Kills Cancer Cells by Shao, Chang, Lu, Wenjie, Wan, Ning, Wu, Mengqiu, Bao, Qiuyu, Tian, Yang, Lu, Gaoyuan, Wang, Nian, Hao, Haiping, Ye, Hui

“…Metronomic chemotherapy, a relatively new dosing paradigm for anticancer therapy, is an alternative to traditional chemotherapy that uses maximal tolerated…”
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Sub-residue Resolution Footprinting of Ligand-Protein Interactions by Carbene Chemistry and Ion Mobility-Mass Spectrometry by Lu, Gaoyuan, Xu, Xiaowei, Li, Gongyu, Sun, Huiyong, Wang, Nian, Zhu, Yinxue, Wan, Ning, Shi, Yatao, Wang, Guangji, Li, Lingjun, Hao, Haiping, Ye, Hui

“…The knowledge of ligand-protein interactions is essential for understanding fundamental biological processes and for the rational design of drugs that target…”
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