Search Results - "Lu, Daniel C."
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Noninvasive Reactivation of Motor Descending Control after Paralysis
Published in Journal of neurotrauma (15-12-2015)“…The present prognosis for the recovery of voluntary control of movement in patients diagnosed as motor complete is generally poor. Herein we introduce a novel…”
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2
Molecular and cellular development of spinal cord locomotor circuitry
Published in Frontiers in molecular neuroscience (16-06-2015)“…The spinal cord of vertebrate animals is comprised of intrinsic circuits that are capable of sensing the environment and generating complex motor behaviors…”
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3
Weight Bearing Over-ground Stepping in an Exoskeleton with Non-invasive Spinal Cord Neuromodulation after Motor Complete Paraplegia
Published in Frontiers in neuroscience (08-06-2017)“…We asked whether coordinated voluntary movement of the lower limbs could be regained in an individual having been completely paralyzed (>4 year) and completely…”
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Model-based analysis of the acute effects of transcutaneous magnetic spinal cord stimulation on micturition after spinal cord injury in humans
Published in PLoS computational biology (01-07-2024)“…After spinal cord injuries (SCIs), patients may develop either detrusor-sphincter dyssynergia (DSD) or urinary incontinence, depending on the level of the…”
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Engaging Cervical Spinal Cord Networks to Reenable Volitional Control of Hand Function in Tetraplegic Patients
Published in Neurorehabilitation and neural repair (01-11-2016)“…Background. Paralysis of the upper limbs from spinal cord injury results in an enormous loss of independence in an individual’s daily life. Meaningful…”
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Electrical neuromodulation of the cervical spinal cord facilitates forelimb skilled function recovery in spinal cord injured rats
Published in Experimental neurology (01-05-2017)“…Enabling motor control by epidural electrical stimulation of the spinal cord is a promising therapeutic technique for the recovery of motor function after a…”
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Initiation of bladder voiding with epidural stimulation in paralyzed, step trained rats
Published in PloS one (29-09-2014)“…The inability to control timely bladder emptying is one of the most serious challenges among the several functional deficits that occur after a complete spinal…”
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THE USE OF ALLOGRAFT OR AUTOGRAFT AND EXPANDABLE TITANIUM CAGES FOR THE TREATMENT OF VERTEBRAL OSTEOMYELITIS
Published in Neurosurgery (01-01-2009)“…Abstract OBJECTIVE The results of the surgical treatment of osteomyelitis with expandable titanium cages and either allograft or autograft are presented…”
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Minimal handgrip force is needed for transcutaneous electrical stimulation to improve hand functions of patients with severe spinal cord injury
Published in Scientific reports (11-05-2022)“…Spinal cord stimulation enhanced restoration of motor function following spinal cord injury (SCI) in unblinded studies. To determine whether training combined…”
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10
Machine learning classifies predictive kinematic features in a mouse model of neurodegeneration
Published in Scientific reports (17-02-2021)“…Motor deficits are observed in Alzheimer’s disease (AD) prior to the appearance of cognitive symptoms. To investigate the role of amyloid proteins in gait…”
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11
Impaired olfaction in mice lacking aquaporin-4 water channels
Published in The FASEB journal (01-09-2008)“…Aquaporin-4 (AQP4) is a water-selective transport protein expressed in glial cells throughout the central nervous system. AQP4 deletion in mice produces…”
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Objectively quantifying walking ability in degenerative spinal disorder patients using sensor equipped smart shoes
Published in Medical engineering & physics (01-05-2016)“…Highlights • The functional level of LSS patients is quantified using a pair of sensorized shoes. • Machine learning algorithms were used to estimate the…”
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Machine learning predicts improvement of functional outcomes in traumatic brain injury patients after inpatient rehabilitation
Published in Frontiers in rehabilitation sciences (22-09-2022)“…Survivors of traumatic brain injury (TBI) have an unpredictable clinical course. This unpredictability makes clinical resource allocation for clinicians and…”
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14
Clinical presentation and surgical management of intramedullary spinal cord cavernous malformations
Published in Neurosurgical focus (01-09-2010)“…Intramedullary cavernous malformation (CM) is a rare entity, accounting for 5% of all intraspinal lesions. The objective in this study was to define the…”
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15
Rotational Vertebral Artery Occlusion—Series of 9 Cases
Published in Neurosurgery (01-10-2010)“…Abstract BACKGROUND: Rotational vertebral artery syndrome (RVAS) is a rare entity about which previously published studies are mostly limited to individual…”
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Identifying predictors for postoperative clinical outcome in lumbar spinal stenosis patients using smart-shoe technology
Published in Journal of neuroengineering and rehabilitation (18-07-2017)“…Approximately 33% of the patients with lumbar spinal stenosis (LSS) who undergo surgery are not satisfied with their postoperative clinical outcomes…”
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Neurosurgical Management of Interspinous Device Complications: A Case Series
Published in Frontiers in surgery (16-03-2022)“…Best practice guidelines for treating lumbar stenosis include a multidisciplinary approach, ranging from conservative management with physical therapy,…”
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Rotational vertebral artery occlusion secondary to adjacent-level degeneration following anterior cervical discectomy and fusion
Published in Journal of neurosurgery. Spine (01-06-2014)“…Rotational vertebral artery occlusion (RVAO), or bow hunter's syndrome, most often occurs at the C1-2 level on physiological head rotation. It presents with…”
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Free-hand thoracic pedicle screws placed by neurosurgery residents: a CT analysis
Published in European spine journal (01-05-2010)“…Free-hand thoracic pedicle screw placement is becoming more prevalent within neurosurgery residency training programs. This technique implements anatomic…”
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Neuromodulation of the Lumbar Spinal Locomotor Circuit
Published in Neurosurgery clinics of North America (2014)“…The lumbar spinal cord contains the necessary circuitry to independently drive locomotor behaviors. This function is retained following spinal cord injury…”
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