Search Results - "Lu, Chuan‐en"
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1
Fluorescence lifetime metabolic mapping of hypoxia‐induced damage in pancreatic pseudo‐islets
Published in Journal of biophotonics (01-12-2020)“…Pancreatic islet isolation from donor pancreases is an essential step for the transplantation of insulin‐secreting β‐cells as a therapy to treat type 1…”
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2
Monitoring the macrophage response towards biomaterial implants using label-free imaging
Published in Materials today bio (01-08-2023)“…Understanding the immune system's foreign body response (FBR) is essential when developing and validating a biomaterial. Macrophage activation and…”
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Raman microspectroscopy identifies fibrotic tissues in collagen-related disorders via deconvoluted collagen type I spectra
Published in Acta biomaterialia (01-05-2023)“…Fibrosis is a consequence of the pathological remodeling of extracellular matrix (ECM) structures in the connective tissue of an organ. It is often caused by…”
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Decorin improves human pancreatic β-cell function and regulates ECM expression in vitro
Published in Matrix biology (01-01-2023)“…•Treatment with recombinantly-produced DCN results in a significant upregulation of glucose-stimulated insulin secretion of human β-cells in…”
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The Foreign Body Response to an Implantable Therapeutic Reservoir in a Diabetic Rodent Model
Published in Tissue engineering. Part C, Methods (01-10-2021)“…Advancements in type 1 diabetes mellitus treatments have vastly improved in recent years. The move toward a bioartificial pancreas and other fully implantable…”
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Type 1 diabetes and engineering enhanced islet transplantation
Published in Advanced drug delivery reviews (01-10-2022)“…The development of new therapeutic approaches to treat type 1 diabetes mellitus (T1D) relies on the precise understanding and deciphering of insulin-secreting…”
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