Effect of magnesium, acetylsalicilic acid and emoxypine on aggregation of platelets

The thrombin-induced platelet aggregation was studied in the absence and presence of magnesium sulfate, acetylsalicylic acid and emoxypine. It was found that all the preparations studied were able separately to decrease platelet aggregation. In contrast, their joint action was not able to affect the...

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Bibliographic Details
Published in:	Biofizika Vol. 59; no. 6; p. 1108
Main Authors:	Loznikova, S Zh, Sukhodola, A A, Shcharbina, N Iu, Shcharbin, D G
Format:	Journal Article
Language:	Russian
Published:	Russia (Federation) 01-11-2014
Subjects:	Aspirin - pharmacology Blood Platelets - metabolism Brain Ischemia - drug therapy Brain Ischemia - metabolism Female Humans Magnesium - pharmacology Male Picolines - pharmacology Platelet Aggregation - drug effects Platelet Aggregation Inhibitors - pharmacology Stroke - drug therapy Stroke - metabolism
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Summary:	The thrombin-induced platelet aggregation was studied in the absence and presence of magnesium sulfate, acetylsalicylic acid and emoxypine. It was found that all the preparations studied were able separately to decrease platelet aggregation. In contrast, their joint action was not able to affect the aggregation of platelets. The data obtained can be used to choose the treatment strategy for patients with ischemic stroke.
ISSN:	0006-3029