Search Results - "Lozinskaya, A."
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Microwave-Assisted Synthesis of 3-Hydroxy-2-oxindoles and Pilot Evaluation of Their Antiglaucomic Activity
Published in International journal of molecular sciences (01-03-2023)“…Glaucoma is a widespread neurodegenerative disease for which increased intraocular pressure (IOP) is a primary modifiable risk factor. Recently, we have…”
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2
Synthesis of New 2,3-Dihydroindole Derivatives and Evaluation of Their Melatonin Receptor Binding Affinity
Published in Molecules (Basel, Switzerland) (01-11-2022)“…2,3-Dihydroindoles are promising agents for the synthesis of new compounds with neuroprotective and antioxidant properties. Usually, these compounds are…”
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3
3-Arylidene-2-oxindoles as Potent NRH:Quinone Oxidoreductase 2 Inhibitors
Published in Molecules (Basel, Switzerland) (25-01-2023)“…The enzyme NRH:quinone oxidoreductase 2 (NQO2) plays an important role in the pathogenesis of various diseases such as neurodegenerative disorders, malaria,…”
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4
Optical and infrared emission of H ii complexes as a clue to the PAH life cycle
Published in Monthly notices of the Royal Astronomical Society (11-10-2014)“…We present an analysis of optical spectroscopy and infrared aperture photometry of more than 100 H ii complexes in nine galaxies. Spectra obtained with the 6-m…”
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5
Synthetic Design and Biological Evaluation of New p53-MDM2 Interaction Inhibitors Based on Imidazoline Core
Published in Pharmaceuticals (Basel, Switzerland) (02-04-2022)“…The use of p53-MDM2 inhibitors is a prospective strategy in anti-cancer therapy for tumors expressing wild type p53 protein. In this study, we have applied a…”
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6
Hymecromone Administration in Real Clinical Practice: Results of the Prospective Multicentre Observational Study in the Republic of Kazakhstan
Published in Rossiĭskiĭ zhurnal gastroėnterologii, gepatologii, koloproktologii (02-01-2022)“…Introduction . This multicentre prospective non-interventional observational study was conducted to obtain additional data about Odeston efficacy and safety in…”
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7
Chromium compensated gallium arsenide detectors for X-ray and γ-ray spectroscopic imaging
Published in Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment (11-07-2014)“…Semi-insulating GaAs material of 500μm thickness grown using the Liquid Encapsulated Czochralski (LEC) method has been compensated with chromium to produce…”
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8
Complexes of triggered star formation in supergiant shell of Holmberg II
Published in Monthly notices of the Royal Astronomical Society (11-01-2017)“…We report a detailed analysis of all regions of current star formation in the walls of the supergiant H I shell (SGS) in the galaxy Holmberg II based on…”
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9
Anticorrosive characteristics of imidazole derivative on carbon steel in 1 M HCl
Published in Journal of electrochemical science and engineering (09-04-2024)“…The novelty of the work is to scrutinize for the first time the 4R,5S- 2,4,5-tris(4-ethoxyphenyl)-4,5-dihydro-1H-imidazole (TEPI) as a corrosion inhibitor for…”
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10
Ionized gas velocity dispersion in nearby dwarf galaxies: looking at supersonic turbulent motions
Published in Monthly notices of the Royal Astronomical Society (01-06-2012)“…We present the results of an ionized gas turbulent motions study in several nearby dwarf galaxies using a scanning Fabry-Perot interferometer with the 6-m…”
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11
Virtual and experimental screening of new melatonin bioisosteres for the treatment of glaucoma
Published in Acta biomedica scientifica (26-03-2024)“…Background . Melatonin is an endogenous regulator of intraocular pressure (IOP), but its effectiveness as a drug for glaucoma treatment is limited. The aim…”
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12
Diastereoselective Synthesis of Meso‐1,2‐Diarylethane‐1,2‐Diamines Via Sodium Reduction of Imidazolines
Published in Asian journal of organic chemistry (01-11-2024)“…A facile method for the preparation of meso‐1,2‐diarylethane‐1,2‐diamines from aromatic aldehydes is disclosed. The stereoselectivity of the protocol is based…”
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13
Thiouronium Salt Derivatives Based on Vicinal Diamines as Potential Neuroprotectors
Published in Bezopasnostʹ i risk farmakoterapii (Online) (01-06-2023)“…Most of the medicinal products that are currently approved and used in clinical practice for neurodegenerative diseases, in particular Alzheimer’s disease,…”
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14
Stellar feedback impact on the ionized gas kinematics in the dwarf galaxy Sextans B
Published in Monthly notices of the Royal Astronomical Society (06-03-2024)“…ABSTRACT We investigated the ionized and atomic gas kinematics and excitation state in the central region of ongoing star formation of the nearby…”
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15
Stellar feedback impact on the ionized gas kinematics in the dwarf galaxy Sextans A
Published in Monthly notices of the Royal Astronomical Society (07-11-2022)“…ABSTRACT Feedback from massive stars shapes the interstellar medium (ISM) and affects the evolution of galaxies, but its mechanisms acting at the small scales…”
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16
Star formation in the nearby dwarf galaxy DDO 53: interplay between gas accretion and stellar feedback
Published in Monthly notices of the Royal Astronomical Society (01-12-2021)“…ABSTRACT We present the results of a multiwavelength study of the nearby dwarf galaxy DDO 53 – a relatively isolated member of the M 81 group. We analyse the…”
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17
The rational design of novel 5-amino-2-oxindole derivatives with antiglaucomic activity
Published in Bioorganic & medicinal chemistry letters (15-06-2023)“…[Display omitted] Compounds with a 2-oxindole scaffold play an important role in organic synthesis and especially in the synthesis of bioactive organic…”
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18
A synchrotron superbubble in the IC 10 galaxy: a hypernova remnant?
Published in Monthly notices of the Royal Astronomical Society. Letters (01-10-2007)“…The nature of the synchrotron superbubble in the IC 10 galaxy is discussed using the results of our investigation of its ionized gas structure, kinematics and…”
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19
Melatonin and its bioisosteres as potential therapeutic agents for the treatment of retinopathy of prematurity
Published in Chemical biology & drug design (01-03-2024)“…We conducted a study on the impact of intraperitoneal injections of melatonin and its three bioisosteres (compounds 1–3) on the development of oxygen‐induced…”
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Towards multi-target antidiabetic agents: In vitro and in vivo evaluation of 3,5-disubstituted indolin-2-one derivatives as novel α-glucosidase inhibitors
Published in Bioorganic & medicinal chemistry letters (01-01-2022)“…[Display omitted] Type 2 diabetes mellitus is a chronic progressive disease that usually requires polypharmacological treatment approaches. Previously we have…”
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