Search Results - "Loyens, Ellen"
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1
VEGF modulates NMDA receptors activity in cerebellar granule cells through Src-family kinases before synapse formation
Published in Proceedings of the National Academy of Sciences - PNAS (16-08-2011)“…NMDA type glutamate receptors (NMDARs) are best known for their role in synaptogenesis and synaptic plasticity. Much less is known about their developmental…”
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Journal Article -
2
Assessment of the convulsant liability of antidepressants using zebrafish and mouse seizure models
Published in Epilepsy & behavior (01-11-2011)“…Abstract In the past, antidepressants have been thought to possess proconvulsant properties. This assumption remains controversial, however, because…”
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3
l-Theanine intake increases threshold for limbic seizures but decreases threshold for generalized seizures
Published in Nutritional neuroscience (01-03-2013)“…l-Theanine, an ethylamide derivate of glutamate found in abundance in green tea, has been shown to exert beneficial actions in animal models for several…”
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Journal Article -
4
Effects of AT1 receptor antagonism on kainate-induced seizures and concomitant changes in hippocampal extracellular noradrenaline, serotonin, and dopamine levels in Wistar-Kyoto and spontaneously hypertensive rats
Published in Epilepsy & behavior (01-05-2015)“…Abstract In the management of epilepsy, AT1 receptor antagonists have been suggested as an additional treatment strategy. A hyperactive brain angiotensin (Ang)…”
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Journal Article -
5
Loss of System xc− Does Not Induce Oxidative Stress But Decreases Extracellular Glutamate in Hippocampus and Influences Spatial Working Memory and Limbic Seizure Susceptibility
Published in The Journal of neuroscience (13-04-2011)“…System x c − exchanges intracellular glutamate for extracellular cystine, giving it a potential role in intracellular glutathione synthesis and nonvesicular…”
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Journal Article -
6
Region- and age-specific changes in glutamate transport in the AβPP23 mouse model for Alzheimer's disease
Published in Journal of Alzheimer's disease (01-01-2011)“…Using 8- and 18-month-old AβPP23 mice, we investigated the involvement of high-affinity glutamate transporters (GLAST, GLT-1, EAAC1), vesicular glutamate…”
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Journal Article -
7
Antidepressant-like effects of oxytocin in mice are dependent on the presence of insulin-regulated aminopeptidase
Published in The international journal of neuropsychopharmacology (01-06-2013)“…Oxytocin is a neuromodulator with antidepressant-like effects. In vitro, oxytocin is rapidly cleaved by insulin-regulated aminopeptidase (IRAP). Oxytocin…”
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Journal Article -
8
Trans-Modulation of the Somatostatin Type 2A Receptor Trafficking by Insulin-Regulated Aminopeptidase Decreases Limbic Seizures
Published in The Journal of neuroscience (26-08-2015)“…Within the hippocampus, the major somatostatin (SRIF) receptor subtype, the sst2A receptor, is localized at postsynaptic sites of the principal neurons where…”
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9
Inactivation of the Constitutively Active Ghrelin Receptor Attenuates Limbic Seizure Activity in Rodents
Published in Neurotherapeutics (01-07-2012)“…Ghrelin is a pleiotropic neuropeptide that has been recently implicated in epilepsy. Animal studies performed to date indicate that ghrelin has anticonvulsant…”
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10
vGLUT2 heterozygous mice show more susceptibility to clonic seizures induced by pentylenetetrazol
Published in Neurochemistry international (2009)“…Glutamate, the most abundant excitatory neurotransmitter in the central nervous system, is well known to be implicated in epileptic seizures. Therefore,…”
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Journal Article Conference Proceeding -
11
Loss of System x c − Does Not Induce Oxidative Stress But Decreases Extracellular Glutamate in Hippocampus and Influences Spatial Working Memory and Limbic Seizure Susceptibility
Published in The Journal of neuroscience (13-04-2011)“…System x c − exchanges intracellular glutamate for extracellular cystine, giving it a potential role in intracellular glutathione synthesis and nonvesicular…”
Get full text
Journal Article -
12
VEGF modulates NMDA receptors activity in cerebellar granule cells through Src-family kinases before synapse formation
Published in Proceedings of the National Academy of Sciences - PNAS (29-07-2011)“…NMDA type glutamate receptors (NMDARs) are best known for their role in synaptogenesis and synaptic plasticity. Much less is known about their developmental…”
Get full text
Journal Article -
13
Loss of system x(c)- does not induce oxidative stress but decreases extracellular glutamate in hippocampus and influences spatial working memory and limbic seizure susceptibility
Published in The Journal of neuroscience (13-04-2011)“…System x(c)- exchanges intracellular glutamate for extracellular cystine, giving it a potential role in intracellular glutathione synthesis and nonvesicular…”
Get full text
Journal Article