Search Results - "Loyd, E"

The Genetics of Pulmonary Arterial Hypertension by Austin, Eric D, Loyd, James E

“…Pulmonary arterial hypertension (PAH) is a progressive and fatal disease for which there is an ever-expanding body of genetic and related pathophysiological…”
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Genetics and genomics of pulmonary arterial hypertension by Morrell, Nicholas W, Aldred, Micheala A, Chung, Wendy K, Elliott, C Gregory, Nichols, William C, Soubrier, Florent, Trembath, Richard C, Loyd, James E

“…Since 2000 there have been major advances in our understanding of the genetic and genomics of pulmonary arterial hypertension (PAH), although there remains…”
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The genetic basis of idiopathic pulmonary fibrosis by Kropski, Jonathan A, Blackwell, Timothy S, Loyd, James E

“…Throughout the past decade, there have been substantial advances in understanding the pathogenesis of idiopathic pulmonary fibrosis (IPF). Recently, several…”
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Genetics and Genomics of Pulmonary Arterial Hypertension by Soubrier, Florent, MD, PhD, Chung, Wendy K., MD, PhD, Machado, Rajiv, PhD, Grünig, Ekkehard, MD, Aldred, Micheala, PhD, Geraci, Mark, MD, Loyd, James E., MD, Elliott, C. Gregory, MD, Trembath, Richard C., MD, Newman, John H., MD, Humbert, Marc, MD, PhD

“…Major discoveries have been obtained within the last decade in the field of hereditary predisposition to pulmonary arterial hypertension (PAH). Among them, the…”
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Single-cell RNA sequencing reveals profibrotic roles of distinct epithelial and mesenchymal lineages in pulmonary fibrosis by Habermann, Arun C, Gutierrez, Austin J, Bui, Linh T, Yahn, Stephanie L, Winters, Nichelle I, Calvi, Carla L, Peter, Lance, Chung, Mei-I, Taylor, Chase J, Jetter, Christopher, Raju, Latha, Roberson, Jamie, Ding, Guixiao, Wood, Lori, Sucre, Jennifer M S, Richmond, Bradley W, Serezani, Ana P, McDonnell, Wyatt J, Mallal, Simon B, Bacchetta, Matthew J, Loyd, James E, Shaver, Ciara M, Ware, Lorraine B, Bremner, Ross, Walia, Rajat, Blackwell, Timothy S, Banovich, Nicholas E, Kropski, Jonathan A

“…Pulmonary fibrosis (PF) is a form of chronic lung disease characterized by pathologic epithelial remodeling and accumulation of extracellular matrix (ECM). To…”
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Clinical Practice Guidelines for the Management of Patients with Histoplasmosis: 2007 Update by the Infectious Diseases Society of America by Wheat, L. Joseph, Freifeld, Alison G., Kleiman, Martin B., Baddley, John W., McKinsey, David S., Loyd, James E., Kauffman, Carol A.

“…Evidence-based guidelines for the management of patients with histoplasmosis were prepared by an Expert Panel of the Infectious Diseases Society of America…”
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Pulmonary Arterial Hypertension: A Current Perspective on Established and Emerging Molecular Genetic Defects by Machado, Rajiv D., Southgate, Laura, Eichstaedt, Christina A., Aldred, Micheala A., Austin, Eric D., Best, D. Hunter, Chung, Wendy K., Benjamin, Nicola, Elliott, C. Gregory, Eyries, Mélanie, Fischer, Christine, Gräf, Stefan, Hinderhofer, Katrin, Humbert, Marc, Keiles, Steven B., Loyd, James E., Morrell, Nicholas W., Newman, John H., Soubrier, Florent, Trembath, Richard C., Viales, Rebecca Rodríguez, Grünig, Ekkehard

“…ABSTRACT Pulmonary arterial hypertension (PAH) is an often fatal disorder resulting from several causes including heterogeneous genetic defects. While…”
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Time for a change: is idiopathic pulmonary fibrosis still idiopathic and only fibrotic? by Wolters, Paul J, Blackwell, Timothy S, Eickelberg, Oliver, Loyd, James E, Kaminski, Naftali, Jenkins, Gisli, Maher, Toby M, Molina-Molina, Maria, Noble, Paul W, Raghu, Ganesh, Richeldi, Luca, Schwarz, Marvin I, Selman, Moises, Wuyts, Wim A, Schwartz, David A

“…Idiopathic pulmonary fibrosis (IPF) is a progressive, irreversible, and typically fatal lung disease characterised by subpleural fibrosis, subepithelial…”
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Genetics and Genomics of Pulmonary Arterial Hypertension by Machado, Rajiv D., PhD, Eickelberg, Oliver, MD, Elliott, C. Gregory, MD, Geraci, Mark W., MD, Hanaoka, Masayuki, MD, PhD, Loyd, James E., MD, Newman, John H., MD, Phillips, John A., MD, Soubrier, Florent, MD, PhD, Trembath, Richard C., BSc, Chung, Wendy K., MD, PhD

“…Pulmonary arterial hypertension (PAH) is a rare disorder that may be hereditable (HPAH), idiopathic (IPAH), or associated with either drug-toxin exposures or…”
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MUC5B Promoter Polymorphism and Interstitial Lung Abnormalities by Hunninghake, Gary M, Hatabu, Hiroto, Okajima, Yuka, Gao, Wei, Dupuis, Josée, Latourelle, Jeanne C, Nishino, Mizuki, Araki, Tetsuro, Zazueta, Oscar E, Kurugol, Sila, Ross, James C, San José Estépar, Raúl, Murphy, Elissa, Steele, Mark P, Loyd, James E, Schwarz, Marvin I, Fingerlin, Tasha E, Rosas, Ivan O, Washko, George R, O'Connor, George T, Schwartz, David A

“…Variants in the gene encoding mucin 5B ( MUC5B ) have been associated with interstitial fibrosis. This study shows a relationship between the presence of the…”
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Diagnosis and Assessment of Pulmonary Arterial Hypertension by Badesch, David B., MD, Champion, Hunter C., MD, PhD, Gomez Sanchez, Miguel Angel, MD, Hoeper, Marius M., MD, Loyd, James E., MD, Manes, Alessandra, MD, PhD, McGoon, Michael, MD, Naeije, Robert, MD, PhD, Olschewski, Horst, MD, Oudiz, Ronald J., MD, Torbicki, Adam, MD, PhD

“…The diagnosis and assessment of pulmonary arterial hypertension is a rapidly evolving area, with changes occurring in the definition of the disease, screening…”
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Critical Genomic Networks and Vasoreactive Variants in Idiopathic Pulmonary Arterial Hypertension by Hemnes, Anna R, Zhao, Min, West, James, Newman, John H, Rich, Stuart, Archer, Stephen L, Robbins, Ivan M, Blackwell, Timothy S, Cogan, Joy, Loyd, James E, Zhao, Zhongming, Gaskill, Christa, Jetter, Christopher, Kropski, Jonathan A, Majka, Susan M, Austin, Eric D

“…Idiopathic pulmonary arterial hypertension (IPAH) is usually without an identified genetic cause, despite clinical and molecular similarity to bone…”
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Longitudinal Analysis Casts Doubt on the Presence of Genetic Anticipation in Heritable Pulmonary Arterial Hypertension by LARKIN, Emma K, NEWMAN, John H, AUSTIN, Eric D, HEMNES, Anna R, WHEELER, Lisa, ROBBINS, Ivan M, WEST, James D, PHILLIPS, John A, HAMID, Rizwan, LOYD, James E

“…Analysis of the age of onset in heritable pulmonary arterial hypertension (HPAH) has led to the hypothesis that genetic anticipation causes younger age of…”
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Obstructive sleep apnea is common in idiopathic pulmonary fibrosis by Lancaster, Lisa H, Mason, Wendi R, Parnell, James A, Rice, Todd W, Loyd, James E, Milstone, Aaron P, Collard, Harold R, Malow, Beth A

“…From 1984 to 2006, studies of sleep in patients with interstitial lung disease revealed disturbed sleep, frequent nocturnal desaturations, nocturnal cough, and…”
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Short telomeres are a risk factor for idiopathic pulmonary fibrosis by Alder, Jonathan K, Chen, Julian J.-L, Lancaster, Lisa, Danoff, Sonye, Su, Shu-chih, Cogan, Joy D, Vulto, Irma, Xie, Mingyi, Qi, Xiaodong, Tuder, Rubin M, Phillips, John A. III, Lansdorp, Peter M, Loyd, James E, Armanios, Mary Y

“…Idiopathic interstitial pneumonias (IIPs) have a progressive and often fatal course, and their enigmatic etiology has complicated approaches to effective…”
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Oestrogen inhibition reverses pulmonary arterial hypertension and associated metabolic defects by Chen, Xinping, Austin, Eric D, Talati, Megha, Fessel, Joshua P, Farber-Eger, Eric H, Brittain, Evan L, Hemnes, Anna R, Loyd, James E, West, James

“…Increased oestrogen is a strong epidemiological risk factor for development of pulmonary arterial hypertension (PAH) in patients, associated with metabolic…”
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Incidence and Progression of Fibrotic Lung Disease in an At-Risk Cohort by Steele, Mark P, Peljto, Anna L, Mathai, Susan K, Humphries, Stephen, Bang, Tami J, Oh, Andrea, Teague, Shawn, Cicchetti, Giuseppe, Sigakis, Christopher, Kropski, Jonathan A, Loyd, James E, Blackwell, Timothy S, Brown, Kevin K, Schwarz, Marvin I, Warren, Rachel A, Powers, Julia, Walts, Avram D, Markin, Cheryl, Fingerlin, Tasha E, Yang, Ivana V, Lynch, David A, Lee, Joyce S, Schwartz, David A

“…Relatives of patients with familial interstitial pneumonia (FIP) are at increased risk for pulmonary fibrosis and develop preclinical pulmonary fibrosis…”
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Bronchoscopic cryobiopsy for the diagnosis of diffuse parenchymal lung disease by Kropski, Jonathan A, Pritchett, Jason M, Mason, Wendi R, Sivarajan, Lakshmi, Gleaves, Linda A, Johnson, Joyce E, Lancaster, Lisa H, Lawson, William E, Blackwell, Timothy S, Steele, Mark P, Loyd, James E, Rickman, Otis B

“…Although in some cases clinical and radiographic features may be sufficient to establish a diagnosis of diffuse parenchymal lung disease (DPLD), surgical lung…”
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Expected Costs of Primary Dental Treatments and Endoscopic Sinus Surgery for Odontogenic Sinusitis by Craig, John R., Tataryn, Roderick W., Sibley, Haley C., Mason, William D., Deuel, Joshua A., Loyd, Gary E., Nerenz, David R., Goyal, Parul

“…Objectives Treatment of odontogenic sinusitis (ODS) due to apical periodontitis (AP) is highly successful when both dental treatment and endoscopic sinus…”
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Serum endostatin is a genetically determined predictor of survival in pulmonary arterial hypertension by Damico, Rachel, Kolb, Todd M, Valera, Lidenys, Wang, Lan, Housten, Traci, Tedford, Ryan J, Kass, David A, Rafaels, Nicholas, Gao, Li, Barnes, Kathleen C, Benza, Raymond L, Rand, James L, Hamid, Rizwan, Loyd, James E, Robbins, Ivan M, Hemnes, Anna R, Chung, Wendy K, Austin, Eric D, Drummond, M Bradley, Mathai, Stephen C, Hassoun, Paul M

“…Pulmonary arterial hypertension (PAH) is a medically incurable disease resulting in death from right ventricular (RV) failure. Both pulmonary vascular and RV…”
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