Search Results - "Loyant, Roxane"

Drug-induced hepatic steatosis in absence of severe mitochondrial dysfunction in HepaRG cells: proof of multiple mechanism-based toxicity by Allard, Julien, Bucher, Simon, Massart, Julie, Ferron, Pierre-Jean, Le Guillou, Dounia, Loyant, Roxane, Daniel, Yoann, Launay, Youenn, Buron, Nelly, Begriche, Karima, Borgne-Sanchez, Annie, Fromenty, Bernard

“…Steatosis is a liver lesion reported with numerous pharmaceuticals. Prior studies showed that severe impairment of mitochondrial fatty acid oxidation (mtFAO)…”
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The Golgi apparatus acts as a platform for TBK1 activation after viral RNA sensing by Pourcelot, Marie, Zemirli, Naima, Silva Da Costa, Leandro, Loyant, Roxane, Garcin, Dominique, Vitour, Damien, Munitic, Ivana, Vazquez, Aimé, Arnoult, Damien

“…After viral infection and the stimulation of some pattern-recognition receptors, TANK-binding kinase I (TBK1) is activated by K63-linked polyubiquitination…”
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Drug-induced impairment of mitochondrial fatty acid oxidation and steatosis: assessment of causal relationship with 45 pharmaceuticals by Buron, Nelly, Porceddu, Mathieu, Loyant, Roxane, Martel, Cécile, Allard, Julien A, Fromenty, Bernard, Borgne-Sanchez, Annie

“…Drug-induced liver injury (DILI) represents a major issue for pharmaceutical companies, being a potential cause of black-box warnings on marketed…”
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Abstract 788: Identification and optimization of pro-apoptotic molecules targeting adenine nucleotide translocator 2 (hANT2) in tumor mitochondria by Buron, Nelly, Pertuiset, Claire, Loyant, Roxane, Martel, Cécile, Porceddu, Mathieu, Borgne-Sanchez, Annie

“…Abstract The mitochondrial protein ANT2 is one of the four isoforms of the ADP/ATP translocase and is expressed in highly proliferating cells. ANT2 plays a…”
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A Fast, Simple, and Affordable Technique to Measure Oxygen Consumption in Living Zebrafish Embryos by Somkhit, Julie, Loyant, Roxane, Brenet, Alexandre, Hassan-Abdi, Rahma, Yanicostas, Constantin, Porceddu, Mathieu, Borgne-Sanchez, Annie, Soussi-Yanicostas, Nadia

“…In all animal species, oxygen consumption is a key process that is partially impaired in a large number of pathological situations and thus provides…”
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