Search Results - "Lowy, R"

The Effect of Advances in Lung-Cancer Treatment on Population Mortality by Howlader, Nadia, Forjaz, Gonçalo, Mooradian, Meghan J, Meza, Rafael, Kong, Chung Yin, Cronin, Kathleen A, Mariotto, Angela B, Lowy, Douglas R, Feuer, Eric J

“…Lung-cancer incidence has been decreasing in part because of a decrease in smoking. However, the decline in population-based mortality from non–small-cell lung…”
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Toward a Shared Vision for Cancer Genomic Data by Grossman, Robert L, Heath, Allison P, Ferretti, Vincent, Varmus, Harold E, Lowy, Douglas R, Kibbe, Warren A, Staudt, Louis M

“…The Genomic Data Commons will initially house raw genomic data and diagnostic, histologic, and clinical outcome data from National Cancer Institute–funded…”
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The next horizon in precision oncology: Proteogenomics to inform cancer diagnosis and treatment by Rodriguez, Henry, Zenklusen, Jean Claude, Staudt, Louis M., Doroshow, James H., Lowy, Douglas R.

“…When it comes to precision oncology, proteogenomics may provide better prospects to the clinical characterization of tumors, help make a more accurate…”
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Aiming High — Changing the Trajectory for Cancer by Lowy, Douglas R, Collins, Francis S

“…The coalescence of new scientific insights and technological innovations has improved our prospects for success against cancer. The cancer “moonshot” aims to…”
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Optimizing reduction of western blotting analytical variations: Use of replicate test samples, multiple normalization methods, and sample loading positions by Rees, Phyllis A., Lowy, R. Joel

“…Western blot (WB) analysis is widely used, but obtaining consistent results can be problematic, especially when using multiple gels. This study examines WB…”
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HPV prophylactic vaccines and the potential prevention of noncervical cancers in both men and women by Gillison, Maura L., Chaturvedi, Anil K., Lowy, Douglas R.

“…Human papillomavirus (HPV) is a necessary cause of cervical cancer. In addition, on the basis of the fulfillment of a combination of viral as well as…”
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An Introduction to Virus Infections and Human Cancer by Schiller, John T, Lowy, Douglas R

“…Approximately, 1.4 million virus-induced cancers occur annually, representing roughly 10% of the worldwide cancer burden, with the majority (> 85%) occurring…”
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Reducing HPV-associated cancer globally by Lowy, Douglas R, Schiller, John T

“…Human papillomavirus (HPV)-related cancers are a major worldwide public health concern. Virtually all cervical cancer is HPV related, with 70% caused by HPV16…”
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Evaluation of Durability of a Single Dose of the Bivalent HPV Vaccine: The CVT Trial by Kreimer, Aimée R, Sampson, Joshua N, Porras, Carolina, Schiller, John T, Kemp, Troy, Herrero, Rolando, Wagner, Sarah, Boland, Joseph, Schussler, John, Lowy, Douglas R, Chanock, Stephen, Roberson, David, Sierra, Mónica S, Tsang, Sabrina H, Schiffman, Mark, Rodriguez, Ana Cecilia, Cortes, Bernal, Gail, Mitchell H, Hildesheim, Allan, Gonzalez, Paula, Pinto, Ligia A

“…Abstract Background The authors investigated the durability of vaccine efficacy (VE) against human papillomavirus (HPV)16 or 18 infections and antibody…”
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Primary endpoints for future prophylactic human papillomavirus vaccine trials: towards infection and immunobridging by Lowy, Douglas R, Dr, Herrero, Rolando, MD, Hildesheim, Allan, PhD

“…Summary Although available human papillomavirus (HPV) vaccines have high efficacy against incident infection and disease caused by HPV types that they…”
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LD Motif Recognition by Talin: Structure of the Talin-DLC1 Complex by Zacharchenko, Thomas, Qian, Xiaolan, Goult, Benjamin T., Jethwa, Devina, Almeida, Teresa B., Ballestrem, Christoph, Critchley, David R., Lowy, Douglas R., Barsukov, Igor L.

“…Cell migration requires coordination between integrin-mediated cell adhesion to the extracellular matrix and force applied to adhesion sites. Talin plays a key…”
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Prophylactic human papillomavirus vaccines by Lowy, Douglas R, Schiller, John T

“…Human papillomavirus (HPV) infection causes virtually all cases of cervical cancer, the second most common cause of death from cancer among women worldwide…”
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Gain-of-Function RHOA Mutations Promote Focal Adhesion Kinase Activation and Dependency in Diffuse Gastric Cancer by Zhang, Haisheng, Schaefer, Antje, Wang, Yichen, Hodge, Richard G, Blake, Devon R, Diehl, J Nathaniel, Papageorge, Alex G, Stachler, Matthew D, Liao, Jennifer, Zhou, Jin, Wu, Zhong, Akarca, Fahire G, de Klerk, Leonie K, Derks, Sarah, Pierobon, Mariaelena, Hoadley, Katherine A, Wang, Timothy C, Church, George, Wong, Kwok-Kin, Petricoin, Emanuel F, Cox, Adrienne D, Lowy, Douglas R, Der, Channing J, Bass, Adam J

“…Diffuse gastric cancer (DGC) is a lethal malignancy lacking effective systemic therapy. Among the most provocative recent results in DGC has been that of…”
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Chapter 12: Prophylactic HPV vaccines: Underlying mechanisms by Stanley, Margaret, Lowy, Douglas R., Frazer, Ian

“…Human papillomavirus virus-like particles (HPV VLP) can be generated by the synthesis and self-assembly in vitro of the major virus capsid protein L1. HPV L1…”
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Durability of Cross-Protection by Different Schedules of the Bivalent HPV Vaccine: The CVT Trial by Tsang, Sabrina H, Sampson, Joshua N, Schussler, John, Porras, Carolina, Wagner, Sarah, Boland, Joseph, Cortes, Bernal, Lowy, Douglas R, Schiller, John T, Schiffman, Mark, Kemp, Troy J, Rodriguez, Ana Cecilia, Quint, Wim, Gail, Mitchell H, Pinto, Ligia A, Gonzalez, Paula, Hildesheim, Allan, Kreimer, Aimée R, Herrero, Rolando

“…Abstract Background The Costa Rica HPV Vaccine Trial has documented cross-protection of the bivalent HPV vaccine against HPV31/33/45 up to 7 years after…”
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Efficient Intracellular Assembly of Papillomaviral Vectors by BUCK, Christopher B, PASTRANA, Diana V, LOWY, Douglas R, SCHILLER, John T

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Genital transmission of HPV in a mouse model is potentiated by nonoxynol-9 and inhibited by carrageenan by Schiller, John T, Roberts, Jeffrey N, Buck, Christopher B, Thompson, Cynthia D, Kines, Rhonda, Bernardo, Marcelino, Choyke, Peter L, Lowy, Douglas R

“…Genital human papillomavirus (HPV) infection is the most common sexually transmitted infection, and virtually all cases of cervical cancer are attributable to…”
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initial steps leading to papillomavirus infection occur on the basement membrane prior to cell surface binding by Kines, Rhonda C, Thompson, Cynthia D, Lowy, Douglas R, Schiller, John T, Day, Patricia M

“…Using a murine challenge model, we previously determined that human papillomavirus (HPV) pseudovirions initially bind preferentially to the cervicovaginal…”
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Identification of a Role for the trans-Golgi Network in Human Papillomavirus 16 Pseudovirus Infection by Day, Patricia M, Thompson, Cynthia D, Schowalter, Rachel M, Lowy, Douglas R, Schiller, John T

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Measuring type I interferon using reporter gene assays based on readily available cell lines by Rees, Phyllis A., Lowy, R. Joel

“…Cell lines stably transfected with genes responding to Type I interferons (IFN) are potentially a useful alternative to enzyme linked immuo-assays (ELISAs) or…”
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