Search Results - "Lowry, R"

Emerging roles of microglial cathepsins in neurodegenerative disease by Lowry, Jessica R., Klegeris, Andis

“…•Alzheimer-specific pathological structures cause adverse microglial activation.•Cathepsins B, D and S regulate microglial neuroimmune responses.•Specific…”
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Craniofacial Microsomia, Associated Congenital Anomalies, and Risk Factors in 63 Cases from the Alberta Congenital Anomalies Surveillance System by Thomas, Mary Ann, Bedard, Tanya, Crawford, Susan, Grevers, Xin, Lowry, R. Brian

“…To report associated congenital anomalies with unexplained craniofacial microsomia (CFM) and the phenotypic overlap with other recurrent constellations of…”
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USArray Imaging of Continental Crust in the Conterminous United States by Ma, Xiaofei, Lowry, Anthony R.

“…The thickness and bulk composition of continental crust provide important constraints on the evolution and dynamics of continents. Crustal mineralogy and…”
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Prenatal findings in 11 cases with craniofacial microsomia using the Alberta Congenital Anomalies Surveillance System, 1997–2019 by Thomas, Mary Ann, Bedard, Tanya, Crawford, Susan, Lowry, R. Brian

“…Craniofacial microsomia (CFM) primarily includes specific head and neck anomalies that co‐occur more frequently than expected. The anomalies are usually…”
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Disease coding systems for arthrogryposis multiplex congenita by Bedard, Tanya, Lowry, R. Brian

“…Arthrogryposis multiplex congenita (AMC) encompasses many different conditions, involves many different genes and thus can be very complex. Using historical…”
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Reduction in Neural-Tube Defects after Folic Acid Fortification in Canada by De Wals, Philippe, Tairou, Fassiatou, Van Allen, Margot I, Uh, Soo-Hong, Lowry, R. Brian, Sibbald, Barbara, Evans, Jane A, Van den Hof, Michiel C, Zimmer, Pamela, Crowley, Marian, Fernandez, Bridget, Lee, Nora S, Niyonsenga, Theophile

“…In 1998, fortification of cereal products with folic acid became mandatory in Canada. The authors assessed the prevalence of neural-tube defects in seven…”
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PI3K/Akt signaling requires spatial compartmentalization in plasma membrane microdomains by Gao, Xinxin, Lowry, Pamela R, Zhou, Xin, Depry, Charlene, Wei, Zhikui, Wong, G. William, Zhang, Jin

“…Spatial compartmentalization of signaling pathway components generally defines the specificity and enhances the efficiency of signal transduction. The…”
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Dynamic Visualization of mTORC1 Activity in Living Cells by Zhou, Xin, Clister, Terri L., Lowry, Pamela R., Seldin, Marcus M., Wong, G. William, Zhang, Jin

“…The mechanistic target of rapamycin complex 1 (mTORC1) senses diverse signals to regulate cell growth and metabolism. It has become increasingly clear that…”
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Development of MAP4 Kinase Inhibitors as Motor Neuron-Protecting Agents by Bos, Pieter H, Lowry, Emily R, Costa, Jonathon, Thams, Sebastian, Garcia-Diaz, Alejandro, Zask, Arie, Wichterle, Hynek, Stockwell, Brent R

“…Disease-causing mutations in many neurodegenerative disorders lead to proteinopathies that trigger endoplasmic reticulum (ER) stress. However, few therapeutic…”
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High-Temperature Properties and Ferroelastic Phase Transitions in Rare-Earth Niobates (LnNbO4) by Sarin, Pankaj, Hughes, Robert W., Lowry, Daniel R., Apostolov, Zlatomir D., Kriven, Waltraud M.

“…Phase transition and high‐temperature properties of rare‐earth niobates (LnNbO4, where Ln = La, Dy and Y) were studied in situ at high temperatures using…”
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Axenfeld-Rieger syndrome: more than meets the eye by Reis, Linda M, Maheshwari, Mohit, Capasso, Jenina, Atilla, Huban, Dudakova, Lubica, Thompson, Samuel, Zitano, Lia, Lay-Son, Guillermo, Lowry, R Brian, Black, Jennifer, Lee, Joseph, Shue, Ann, Kremlikova Pourova, Radka, Vaneckova, Manuela, Skalicka, Pavlina, Jedlickova, Jana, Trkova, Marie, Williams, Bradley, Richard, Gabriele, Bachman, Kristine, Seeley, Andrea H, Costakos, Deborah, Glaser, Thomas M, Levin, Alex V, Liskova, Petra, Murray, Jeffrey C, Semina, Elena V

“…Axenfeld-Rieger syndrome (ARS) is characterised by typical anterior segment anomalies, with or without systemic features. The discovery of causative genes…”
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Hypospadias Prevalence and Trends in International Birth Defect Surveillance Systems, 1980–2010 by Yu, Xiao, Nassar, Natasha, Mastroiacovo, Pierpaolo, Canfield, Mark, Groisman, Boris, Bermejo-Sánchez, Eva, Ritvanen, Annukka, Kiuru-Kuhlefelt, Sonja, Benavides, Adriana, Sipek, Antonin, Pierini, Anna, Bianchi, Fabrizio, Källén, Karin, Gatt, Miriam, Morgan, Margery, Tucker, David, Canessa, M. Aaurora, Gajardo, Rosa, Mutchinick, Osvaldo M., Szabova, Elena, Csáky-Szunyogh, Melinda, Tagliabue, Giovanna, Cragan, Janet D., Nembhard, Wendy N., Rissmann, Anke, Goetz, Dorit, Bower, Carol, Baynam, Gareth, Lowry, R. Brian, Leon, Juan A., Luo, Wei, Rouleau, Jocelyn, Zarante, Ignacio, Fernandez, Nicolas, Amar, Emmanuelle, Dastgiri, Saeed, Contiero, Paolo, Martínez-de-Villarreal, Laura E., Borman, Barry, Bergman, J.E.H., de Walle, Hermien E.K., Hobbs, Charlotte A., Nance, Amy E., Agopian, A.J.

“…Hypospadias is a common male birth defect that has shown widespread variation in reported prevalence estimates. Many countries have reported increasing trends…”
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Mutations in BICD2, which Encodes a Golgin and Important Motor Adaptor, Cause Congenital Autosomal-Dominant Spinal Muscular Atrophy by Neveling, Kornelia, Martinez-Carrera, Lilian A., Hölker, Irmgard, Heister, Angelien, Verrips, Aad, Hosseini-Barkooie, Seyyed Mohsen, Gilissen, Christian, Vermeer, Sascha, Pennings, Maartje, Meijer, Rowdy, te Riele, Margot, Frijns, Catharina J.M., Suchowersky, Oksana, MacLaren, Linda, Rudnik-Schöneborn, Sabine, Sinke, Richard J., Zerres, Klaus, Lowry, R. Brian, Lemmink, Henny H., Garbes, Lutz, Veltman, Joris A., Schelhaas, Helenius J., Scheffer, Hans, Wirth, Brunhilde

“…Spinal muscular atrophy (SMA) is a heterogeneous group of neuromuscular disorders caused by degeneration of lower motor neurons. Although functional loss of…”
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Prevalence of multiple congenital contractures including arthrogryposis multiplex congenita in Alberta, Canada, and a strategy for classification and coding by Lowry, R. Brian, Sibbald, Barbara, Bedard, Tanya, Hall, Judith G.

“…BACKGROUND The population prevalence of multiple congenital contractures, many of which have either arthrogryposis multiplex congenita or amyoplasia congenita,…”
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Triple surveillance: The future for birth defect registries by Lowry, R. Brian, Bedard, Tanya

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Underestimating the impact of water fluoridation by Morris, J., Hearnshaw, S., Rugg-Gunn, A., Jacob, M., Johnson, J., Lowry, R., Cockcroft, B.

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Site Disorder as a Predictor for Compositionally Complex 5RE2Zr2O7 Ceramic Phase Stability by Lowry, Daniel R, Boro, Joseph R, Mia Blea‐Kirby, Valdez, Nichole R, Bishop, Sean R

“…Phase formation and stability of five component compositionally complex rare earth zirconates (5RE2Zr2O7) were investigated by X‐ray diffraction and electron…”
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Resonant slow fault slip in subduction zones forced by climatic load stress by Lowry, Anthony R

“…Global Positioning System (GPS) measurements at subduction plate boundaries often record fault movements similar to earthquakes but much slower, occurring over…”
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Phenotype and pathology of the dilated cardiomyopathy with ataxia syndrome in children by Machiraju, Pranav, Degtiarev, Vlad, Patel, Dhwani, Hazari, Hassan, Lowry, R. Brian, Bedard, Tanya, Sinasac, David, Brundler, Marie‐Anne, Greenway, Steven C., Khan, Aneal

“…The dilated cardiomyopathy with ataxia syndrome (DCMA) is an autosomal recessive mitochondrial disease caused by mutations in the DnaJ heat shock protein…”
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Orofacial clefts in California: No decline in Alberta, Canada by Lowry, R. Brian, Crawford, Susan, Bedard, Tanya, Sibbald, Barbara

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