Search Results - "Lowndes, N.F"

budding yeast Rad9 checkpoint protein is subjected to Mec1/Tel1-dependent hyperphosphorylation and interacts with Rad53 after DNA damage by Vialard, J.E, Gilbert, C.S, Green, C.M, Lowndes, N.F

“…The Saccharomyces cerevisiae RAD9 checkpoint gene is required for transient cell‐cycle arrests and transcriptional induction of DNA repair genes in response to…”
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Role of the Saccharomyces cerevisiae Rad9 protein in sensing and responding to DNA damage by Toh, G W-L, Lowndes, N F

“…Eukaryotic cells have evolved surveillance mechanisms, known as DNA-damage checkpoints, that sense and respond to genome damage. DNA-damage checkpoint pathways…”
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RAD9 and RAD24 define two additive, interacting branches of the DNA damage checkpoint pathway in budding yeast normally required for Rad53 modification and activation by De la Torre-Ruiz, M.A, Green, C.M, Lowndes, N.F

“…In budding yeast, RAD9 and RAD24/RAD17/MEC3 are believed to function upstream of MEC1 and RAD53 in signalling the presence of DNA damage. Deletion of any one…”
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novel role for the budding yeast RAD9 checkpoint gene in DNA damage-dependent transcription by Aboussekhra, A, Vialard, J.E, Morrison, D.E, Torre-Ruiz, M.A. de la, Cernakova, L, Fabre, F, Lowndes, N.F

“…Cells respond to DNA damage by arresting cell cycle progression and activating several DNA repair mechanisms. These responses allow damaged DNA to be repaired…”
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Control of DNA synthesis genes in fission yeast by the cell-cycle gene cdc10 by Lowndes, N.F, McInerny, C.J, Johnson, A.L, Fantes, P.A, Johnston, L.H

“…In the budding yeast Saccharomyces cerevisiae, cell-cycle control over DNA synthesis occurs partly through the coordinate expression in late G1 phase of many,…”
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Cell cycle control of DNA synthesis in budding yeast by Johnston, L.H, Lowndes, N.F

“…The primary cell cycle control over DNA synthesis lies in an event called START. At this point in late G1 the cell assesses the environment and if conditions…”
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SWI6 protein is required for transcription of the periodically expressed DNA synthesis genes in budding yeast by Lowndes, N.F, Johnson, A.L, Breeden, L, Johnston, L.H

“…IN budding yeast many genes are expressed under cell-cycle control in late G1. These include a large group of DNA synthesis genes, the HO gene involved in…”
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Coordination of expression of DNA synthesis genes in budding yeast by a cell-cycle regulated trans factor by Lowndes, N.F, Johnson, A.L, Johnston, L.H

“…All of the DNA synthesis genes of budding yeast examined so far are periodically expressed and hence under cell-cycle control. Expression occurs near the G1/S…”
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yeast DNA ligase gene CDC9 is controlled by six orientation specific upstream activating sequences that respond to cellular proliferation but which alone cannot mediate cell cycle regulation by White, J.H.M, Johnson, A.L, Lowndes, N.F, Johnston, L.H

“…By fusing the CDC9 structural gene to the PGK upstream sequences and the CDC9 upstream to lacZ, we showed that the cell cycle expression of CDC9 is largely due…”
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A cell-cycle-regulated trans-factor, DSC1, controls expression of DNA synthesis genes in yeast by Johnston, L H, Lowndes, N F, Johnson, A L, Sugino, A

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