Search Results - "Lowndes, H.E."

The effect of glutathione depletion on methyl mercury-induced microtubule disassembly in cultured embryonal carcinoma cells by Graff, R D, Philbert, M A, Lowndes, H E, Reuhl, K R

“…Microtubule (MT) assembly and stability are thought to be dependent on intracellular glutathione for the maintenance of critical sulfhydryl groups. Since…”
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Methylmercury Alters Eph and Ephrin Expression During Neuronal Differentiation of P19 Embryonal Carcinoma Cells by Wilson, D.T., Polunas, M.A., Zhou, R., Halladay, A.K., Lowndes, H.E., Reuhl, K.R.

“…Developmental exposure to methylmercury (MeHg) induces a spectrum of neurological impairment characterized by cognitive disturbance, sensory/motor deficit, and…”
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Cellular and regional distribution of reduced glutathione in the nervous system of the rat: histochemical localization by mercury orange and o-phthaldialdehyde-induced histofluorescence by Philbert, M A, Beiswanger, C M, Waters, D K, Reuhl, K R, Lowndes, H E

“…Differences in the cellular distribution of antioxidant defense mechanisms in heterogeneous tissue such as the nervous system are likely critical determinants…”
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Synergistic neurotoxic effects of styrene oxide and acrylamide: glutathione-independent necrosis of cerebellar granule cells by Beiswanger, C M, Mandella, R D, Graessle, T R, Reuhl, K R, Lowndes, H E

“…Conjugation with glutathione (GSH) is a mechanism of detoxification of acrylamide (ACR); hence, prior depletion of GSH might be expected to exacerbate ACR's…”
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Studies on drug-induced neuropathies. III. Motor nerve deficit in cats with experimental acrylamide neuropathy by Lowndes, H E, Baker, T

“…To assess motor nerve and motor nerve terminal function in acrylamide neuropathy, cats were given i.m. injections of acrylamide (15 mg/kg) daily for 10 days to…”
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Dantrolene effects on neuromuscular function in cat soleus muscle by Lowndes, H E

“…Dantrolene sodium (DS) was investigated for its effects on cat soleus muscle contractile properties and motor nerve terminal activity in particular. DS,…”
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