Search Results - "Lowey, S"

Two Heads of Myosin Are Better Than One for Generating Force and Motion by Tyska, M. J., Dupuis, D. E., Guilford, W. H., Patlak, J. B., Waller, G. S., Trybus, K. M., Warshaw, D. M., Lowey, S.

“…Several classes of the myosin superfamily are distinguished by their "double-headed" structure, where each head is a molecular motor capable of hydrolyzing ATP…”
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WHAT WILL MY LIFE BE LIKE AT AGE 70?: PERSPECTIVES OF UNDERGRADUATE STUDENTS IN AN AGING COURSE by Lowey, S

“…The affective domain of learning, according to Bloom’s Taxonomy, is an essential component in the professional development of students’ pursuing a healthcare…”
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Function of skeletal muscle myosin heavy and light chain isoforms by an in vitro motility assay by LOWEY, S, WALLER, G. S, TRYBUS, K. M

“…The functional significance of the large number of myosin isoforms in skeletal muscles is poorly understood. Myosin molecules that have the same heavy chain,…”
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The Essential Light Chain is Required for Full Force Production by Skeletal Muscle Myosin by VanBuren, Peter, Waller, Guillermina S., Harris, David E., Trybus, Kathleen M., Warshaw, David M., Lowey, Susan

“…Myosin, a molecular motor that is responsible for muscle contraction, is composed of two heavy chains each with two light chains. The crystal structure of…”
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Interaction of the N-Terminus of Chicken Skeletal Essential Light Chain 1 with F-Actin by Andreev, O. A, Saraswat, L. D, Lowey, S, Slaughter, C, Borejdo, J

“…Skeletal myosin has two isoforms of the essential light chain (ELC), called LC1 and LC3, which differ only in their N-terminal amino acid sequence. The LC1 has…”
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The Power Stroke Causes Changes in the Orientation and Mobility of the Termini of Essential Light Chain 1 of Myosin by Borejdo, J, Ushakov, D. S, Moreland, R, Akopova, I, Reshetnyak, Y, Saraswat, L. D, Kamm, K, Lowey, S

“…Binding of ATP to the catalytic domain of myosin induces a local conformational change which is believed to cause a major rotation of an 8.5 nm α-helix that is…”
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Mapping Myosin Light Chains by Immunoelectron Microscopy. Use of Anti-Fluorescyl Antibodies as Structural Probes by Katoh, Tsuyoshi, Lowey, Susan

“…The two classes of light chains in vertebrate fast muscle myosin have been selectively labeled with the thiol specific reagent 5-(iodoacetamido) fluorescein to…”
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Role of skeletal and smooth muscle myosin light chains by Lowey, S, Trybus, K M

“…A persistent problem with the rotating cross-bridge model for muscle contraction has been the inability to detect any large conformational changes within the…”
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Conformational states of smooth muscle myosin. Effects of light chain phosphorylation and ionic strength by Trybus, K M, Lowey, S

“…Stoichiometric amounts of MgATP disassemble dephosphorylated smooth muscle and nonmuscle myosin filaments to a 10 S monomer. Phosphorylation of the regulatory…”
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A Bent Monomeric Conformation of Myosin from Smooth Muscle by Trybus, Kathleen M., Huiatt, Ted W., Lowey, Susan

“…Smooth muscle myosin filaments formed in 0.15 M KCl are depolymerized by MgATP to a 10S component, rather than to the 6S component typical of myosin monomer in…”
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The regulatory light chain is required for folding of smooth muscle myosin by Trybus, K M, Lowey, S

“…Light chain phosphorylation causes the folded monomeric form of myosin to extend and assemble into filaments. This observation established the involvement of…”
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Functional Consequences of Mutations in the Myosin Heavy Chain at Sites Implicated in Familial Hypertrophic Cardiomyopathy by Lowey, Susan

“…The primary cause of familial hypertrophic cardiomyopathy (FHC) has been attributed to mutations in the genes that encode the contractile proteins of the…”
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Engineered cysteine mutants of myosin light chain 2. Fluorescent analogues for structural studies by SARASWAT, L. D, LOWEY, S

“…Site-directed mutagenesis has been used to insert cysteine residues at specific locations in the myosin light chain 2 (LC2) sequence. The aim was to modify…”
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Mechanism of smooth muscle myosin phosphorylation by Trybus, K M, Lowey, S

“…In vertebrate smooth muscles, phosphorylation of the regulatory light chain appears to be necessary for actin activation of the Mg-ATPase activity and for the…”
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Crystal Structures of Monomeric Actin Bound to Cytochalasin D by Nair, Usha B., Joel, Peteranne B., Wan, Qun, Lowey, Susan, Rould, Mark A., Trybus, Kathleen M.

“…The fungal toxin cytochalasin D (CD) interferes with the normal dynamics of the actin cytoskeleton by binding to the barbed end of actin filaments. Despite its…”
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Light Chains from Fast and Slow Muscle Myosins by LOWEY, SUSAN, RISBY, DENNIS

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Letting go before a death: a concept analysis by Lowey, Susan E.

“…Title.  Letting go before a death: a concept analysis Aim.  This paper is a report of a concept analysis of letting go within the context of family caregivers…”
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Myosin subunit interactions. Properties of the 19,000-dalton light chain-deficient myosin by Pastra-Landis, S C, Lowey, S

“…The 19,000-dalton light chain (LC2) can be completely and reversibly removed from chicken pectoralis myosin in 1 mM EDTA and 5 mM ATP using immunoaffinity…”
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Myosin subunit interactions. Localization of the alkali light chains by Waller, G S, Lowey, S

“…Myosin homodimers, molecules containing either the A1 or the A2 light chain, do not exchange their light chains under conditions approximating physiological…”
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Subunit Exchange between Smooth Muscle Myosin Filaments by Trybus, Kathleen M., Lowey, Susan

“…Filaments formed from phosphorylated smooth muscle myosin are stable in the presence of MgATP, whereas dephosphorylated filaments are disassembled to a mixture…”
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