Search Results - "Lowell, Jeffrey A"

Involvement of Innate and Adaptive Immune Systems Alterations in the Pathophysiology and Treatment of Depression by Medina-Rodriguez, Eva M, Lowell, Jeffrey A, Worthen, Ryan J, Syed, Shariful A, Beurel, Eléonore

“…Major depressive disorder (MDD) is a prevalent and debilitating disorder, often fatal. Treatment options are few and often do not provide immediate relief to…”
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Outcomes Using Grafts from Donors after Cardiac Death by Doyle, M.B. Majella, MD, FACS, Collins, Kelly, MD, Vachharajani, Neeta, BS, Lowell, Jeffrey A., MD, FACS, Shenoy, Surendra, MD, Nalbantoglu, ILKe, MD, Byrnes, Kathleen, MD, Garonzik-Wang, Jacqueline, MD, Wellen, Jason, MD, FACS, Lin, Yiing, MD, Chapman, William C., MD, FACS

“…Background Previous reports suggest that donation after cardiac death (DCD) liver grafts have increased primary nonfunction (PNF) and cholangiopathy thought to…”
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Outcomes of neoadjuvant transarterial chemoembolization to downstage hepatocellular carcinoma before liver transplantation by Chapman, William C, Majella Doyle, M B, Stuart, Jourdan E, Vachharajani, Neeta, Crippin, Jeffrey S, Anderson, Christopher D, Lowell, Jeffrey A, Shenoy, Surendra, Darcy, Michael D, Brown, Daniel B

“…To evaluate outcomes of downstaging patients with advanced (American liver tumor study group stage III/IV) hepatocellular carcinoma (HCC) with transarterial…”
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Outcomes with Split Liver Transplantation Are Equivalent to Those with Whole Organ Transplantation by Doyle, M.B. Majella, MD, FACS, Maynard, Erin, MD, Lin, Yiing, MD, Vachharajani, Neeta, BS, Shenoy, Surendra, MD, Anderson, Christopher, MD, Earl, Mark, MD, Lowell, Jeffrey A., MD, FACS, Chapman, William C., MD, FACS

“…Background Split liver transplantation is an excellent option for expansion of the donor organ pool. However, reports of increased morbidity in split liver…”
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Th17 cells in depression by Beurel, Eléonore, Lowell, Jeffrey A.

“…•Th17 cells are increased in the blood of depressed patients.•Th17 cells promote depressive-like behaviors in mice.•Th17 cells are pathogenic in most CNS…”
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Donor Age-Based Analysis of Liver Transplantation Outcomes: Short- and Long-Term Outcomes Are Similar Regardless of Donor Age by Chapman, William C., MD, FACS, Vachharajani, Neeta, BS, Collins, Kelly M., MD, Garonzik-Wang, Jackie, MD, Park, Yikyung, ScD, Wellen, Jason R., MD, FACS, Lin, Yiing, MD, PhD, Shenoy, Surendra, MD, PhD, Lowell, Jeffrey A., MD, FACS, Doyle, M.B. Majella, MD, FACS

“…Background The shortage of donor organs has led to increasing use of extended criteria donors, including older donors. The upper limit of donor age that…”
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AAV8 transduction capacity is reduced by prior exposure to endosome-like pH conditions by Lowell, Jeffrey, Mah, Kar, Bixby, John, Lemmon, Vance

“…Adeno-associated virus (AAV) is an essential instrument in the neuroscientist's toolkit, which allows delivery of DNA to provide labeling with fluorescent…”
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Rash from the past: A case of recurrent reactive infectious mucocutaneous eruption triggered by common coronavirus by Lowell, Jeffrey A., Wright, Jervon, Eisenberg, Samuel, Teperman, Jacob, Dastagir, Manile

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Pre-Liver Transplantation Locoregional Adjuvant Therapy for Hepatocellular Carcinoma as a Strategy to Improve Longterm Survival by Bharat, Ankit, Brown, Daniel B., Crippin, Jeffrey S., Gould, Jennifer E., Lowell, Jeffrey A., Shenoy, Surendra, Desai, Niraj M., Chapman, William C.

“…Preorthotopic liver transplantation locoregional therapy (LRT) for hepatocellular carcinoma (HCC) reduces drop-out rates in patients awaiting orthotopic liver…”
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Liver Transplantation for Hepatocellular Carcinoma: Long-Term Results Suggest Excellent Outcomes by Doyle, M.B. Majella, MD, FACS, Vachharajani, Neeta, BS, Maynard, Erin, MD, Shenoy, Surendra, MD, Anderson, Christopher, MD, Wellen, Jason R., MD, FACS, Lowell, Jeffrey A., MD, FACS, Chapman, William C., MD, FACS

“…Background Selected 5-year survival results after liver transplantation for hepatocellular carcinoma (HCC) have been reported to be 70%. Our hypothesis was…”
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Advanced Donor Age Alone Does Not Affect Patient or Graft Survival after Liver Transplantation by Anderson, Christopher D., MD, Vachharajani, Neeta, MB, Doyle, Majella, MD, Lowell, Jeffrey A., MD, FACS, Wellen, Jason R., MD, Shenoy, Surendra, MD, Lisker-Melman, Mauricio, MD, Korenblat, Kevin, MD, Crippin, Jeff, MD, Chapman, William C., MD, FACS

“…Background Individuals greater than 60 years old donate an important portion of the organs available for orthotopic liver transplantation (OLT), but use of…”
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Back to the drawing board: Overview of the next generation of combination therapy for inflammatory bowel disease by Lowell, Jeffrey A, Farber, Michael J, Sultan, Keith

“…Inflammatory bowel disease (IBD) is entering a potentially new era of combined therapeutics. Triantafillidis provide an insightful review of the current state…”
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Pharmacologic Anticoagulation Is Associated With a Lower Risk of Recurrent Venous Thromboembolic Events During Janus Kinase Inhibitor Use for Patients With a Prior Thrombosis by Lowell, Jeffrey A, Sharma, Garvita, Swaminath, Arun, Sultan, Keith

“…Janus kinase (JAK) inhibitors tofacitinib and upadacitinib are effective therapies for inflammatory bowel disease and rheumatologic disorders but currently…”
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Recurrent primary biliary cirrhosis: Peritransplant factors and ursodeoxycholic acid treatment post‐liver transplant by Guy, Jennifer E., Qian, Peiqing, Lowell, Jeffrey A., Peters, Marion G.

“…Primary biliary cirrhosis (PBC) recurs after orthotopic liver transplantation (OLT) in up to one‐third of patients. These patients are typically asymptomatic,…”
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Distinct characteristics of hippocampal pathogenic TH17 cells in a mouse model of depression by Beurel, Eléonore, Lowell, Jeffrey A., Jope, Richard S.

“…•TH17 cells promote depressive-like behavior.•TH17 cells increase in the hippocampus in learned helpless mice.•Hippocampal TH17 cells exhibit pathogenic (CCR6,…”
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Reactive Immunomodulator Addition to Infliximab Monotherapy Restores Clinical Response in Inflammatory Bowel Disease: A Meta-Analysis by Lowell, Jeffrey A., Sharma, Garvita, Chua, Vincent, Ben-Horin, Shomron, Swaminath, Arun, Sultan, Keith

“…Background and Aims Patients with inflammatory bowel disease (IBD) receiving infliximab (IFX) commonly experience immunogenic loss of response (LOR) by…”
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Defective Inflammatory Pathways in Never-Treated Depressed Patients Are Associated with Poor Treatment Response by Syed, Shariful A., Beurel, Eléonore, Loewenstein, David A., Lowell, Jeffrey A., Craighead, W. Edward, Dunlop, Boadie W., Mayberg, Helen S., Dhabhar, Firdaus, Dietrich, W. Dalton, Keane, Robert W., de Rivero Vaccari, Juan Pablo, Nemeroff, Charles B.

“…Inflammation has been involved in the pathophysiology and treatment response of major depressive disorder (MDD). Plasma cytokine profiles of 171…”
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Stressed and Inflamed, Can GSK3 Be Blamed? by Jope, Richard S., Cheng, Yuyan, Lowell, Jeffrey A., Worthen, Ryan J., Sitbon, Yoel H., Beurel, Eleonore

“…Psychological stress has a pervasive influence on our lives. In many cases adapting to stress strengthens organisms, but chronic or severe stress is usually…”
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Small Bowel Obstruction after Pediatric Liver Transplantation: The Unusual Is the Usual by Earl, Truman M., MD, MSCI, Wellen, Jason R., MD, Anderson, Christopher D., MD, Nadler, Michelle, RN, PNP-BC, Doyle, Majella M., MD, Shenoy, Surendra S., MD, PhD, Chapman, William C., MD, FACS, Turmelle, Yumirle, MD, Weymann, Alex, MD, Lowell, Jeffrey A., MD, FACS

“…Background Intestinal obstruction is a rare but serious complication after liver transplantation. Adhesions are the most common cause of obstruction in the…”
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Earlier onset of acute venous thromboembolism with upadacitinib compared with tofacitinib during Janus kinase inhibitor therapy by Lowell, Jeffrey A., Sharma, Garvita, Sultan, Keith

“…[Display omitted]…”
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