Search Results - "Lowe, William"

Continuous Glucose Monitoring in Pregnancy: New Insights Into Gestational Diabetes With More to Learn by Scifres, Christina M, Lowe, William L

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Genetics and Epigenetics: Implications for the Life Course of Gestational Diabetes by Lowe, Jr, William L

“…Gestational diabetes (GDM) is one of the most common complications of pregnancy, affecting as many as one in six pregnancies. It is associated with both short-…”
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Association of Gestational Diabetes With Maternal Disorders of Glucose Metabolism and Childhood Adiposity by Lowe, William L, Scholtens, Denise M, Lowe, Lynn P, Kuang, Alan, Nodzenski, Michael, Talbot, Octavious, Catalano, Patrick M, Linder, Barbara, Brickman, Wendy J, Clayton, Peter, Deerochanawong, Chaicharn, Hamilton, Jill, Josefson, Jami L, Lashley, Michele, Lawrence, Jean M, Lebenthal, Yael, Ma, Ronald, Maresh, Michael, McCance, David, Tam, Wing Hung, Sacks, David A, Dyer, Alan R, Metzger, Boyd E

“…IMPORTANCE: The sequelae of gestational diabetes (GD) by contemporary criteria that diagnose approximately twice as many women as previously used criteria are…”
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Genomic approaches for understanding the genetics of complex disease by Lowe, Jr, William L, Reddy, Timothy E

“…There are thousands of known associations between genetic variants and complex human phenotypes, and the rate of novel discoveries is rapidly increasing…”
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Short chain fatty acids and their receptors: new metabolic targets by Layden, Brian T, Angueira, Anthony R, Brodsky, Michael, Durai, Vivek, Lowe, William L

“…Fatty acids are carboxylic acids with aliphatic tails of different lengths, where short chain fatty acids (SCFAs) typically refer to carboxylic acids with…”
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Path-level interpretation of Gaussian graphical models using the pair-path subscore by Gill, Nathan P, Balasubramanian, Raji, Bain, James R, Muehlbauer, Michael J, Lowe, Jr, William L, Scholtens, Denise M

“…BACKGROUND : Construction of networks from cross-sectional biological data is increasingly common. Many recent methods have been based on Gaussian graphical…”
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Hyperglycemia and Adverse Pregnancy Outcome Follow-up Study (HAPO FUS): Maternal Glycemia and Childhood Glucose Metabolism by Scholtens, Denise M, Kuang, Alan, Lowe, Lynn P, Hamilton, Jill, Lawrence, Jean M, Lebenthal, Yael, Brickman, Wendy J, Clayton, Peter, Ma, Ronald C, McCance, David, Tam, Wing Hung, Catalano, Patrick M, Linder, Barbara, Dyer, Alan R, Lowe, Jr, William L, Metzger, Boyd E

“…This study examined associations of maternal glycemia during pregnancy with childhood glucose outcomes in the Hyperglycemia and Adverse Pregnancy Outcome…”
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Genetics of glucose homeostasis in pregnancy and postpartum by Lowe, Jr, William L, Kuang, Alan, Hayes, M Geoffrey, Hivert, Marie-France, Scholtens, Denise M

“…Pregnancy is accompanied by maternal metabolic adaptations to ensure fetal growth and development, including insulin resistance, which occurs primarily during…”
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Associations of Maternal Cardiovascular Health in Pregnancy With Offspring Cardiovascular Health in Early Adolescence by Perak, Amanda M, Lancki, Nicola, Kuang, Alan, Labarthe, Darwin R, Allen, Norrina B, Shah, Svati H, Lowe, Lynn P, Grobman, William A, Lawrence, Jean M, Lloyd-Jones, Donald M, Lowe, William L, Scholtens, Denise M

“…IMPORTANCE: Pregnancy may be a key window to optimize cardiovascular health (CVH) for the mother and influence lifelong CVH for her child. OBJECTIVE: To…”
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Identification of HKDC1 and BACE2 as Genes Influencing Glycemic Traits During Pregnancy Through Genome-Wide Association Studies by HAYES, M. Geoffrey, URBANEK, Margrit, MCHUGH, Caitlin P, ACKERMAN, Christine M, BOUCHARD, Luigi, BRISSON, Diane, LAYDEN, Brian T, MIREL, Daniel, DOHENY, Kimberly F, LEYA, Marysa V, LOWN-HECHT, Rachel N, DYER, Alan R, HIVERT, Marie-France, METZGER, Boyd E, REDDY, Timothy E, COX, Nancy J, LOWE, William L, ARMSTRONG, Loren L, MORRISON, Jean, CONG GUO, LOWE, Lynn P, SCHEFTNER, Douglas A, PLUZHNIKOV, Anna, LEVINE, David M

“…Maternal metabolism during pregnancy impacts the developing fetus, affecting offspring birth weight and adiposity. This has important implications for…”
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New insights into gestational glucose metabolism: lessons learned from 21st century approaches by Angueira, Anthony R, Ludvik, Anton E, Reddy, Timothy E, Wicksteed, Barton, Lowe, Jr, William L, Layden, Brian T

“…Pregnancy presents a unique physiological challenge that requires changes coordinated by placentally and non-placentally derived hormones to prepare the mother…”
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Metabolomic and genetic architecture of gestational diabetes subtypes by Lee, Kristen, Kuang, Alan, Bain, James R., Hayes, M. Geoffrey, Muehlbauer, Michael J., Ilkayeva, Olga R., Newgard, Christopher B., Powe, Camille E., Hivert, Marie-France, Scholtens, Denise M., Lowe, William L.

“…Aims/hypothesis Physiological gestational diabetes mellitus (GDM) subtypes that may confer different risks for adverse pregnancy outcomes have been defined…”
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Fetal Genotype and Maternal Glucose Have Independent and Additive Effects on Birth Weight by Hughes, Alice E, Nodzenski, Michael, Beaumont, Robin N, Talbot, Octavious, Shields, Beverley M, Scholtens, Denise M, Knight, Bridget A, Lowe, Jr, William L, Hattersley, Andrew T, Freathy, Rachel M

“…Maternal glycemia is a key determinant of birth weight, but recent large-scale genome-wide association studies demonstrated an important contribution of fetal…”
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Maternal glucose levels during pregnancy and childhood adiposity in the Hyperglycemia and Adverse Pregnancy Outcome Follow-up Study by Lowe, William L., Lowe, Lynn P., Kuang, Alan, Catalano, Patrick M., Nodzenski, Michael, Talbot, Octavious, Tam, Wing-Hung, Sacks, David A., McCance, David, Linder, Barbara, Lebenthal, Yael, Lawrence, Jean M., Lashley, Michele, Josefson, Jami L., Hamilton, Jill, Deerochanawong, Chaicharn, Clayton, Peter, Brickman, Wendy J., Dyer, Alan R., Scholtens, Denise M., Metzger, Boyd E.

“…Aims/hypothesis Maternal type 2 diabetes during pregnancy and gestational diabetes are associated with childhood adiposity; however, associations of lower…”
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Epidemic-specific association of maternal exposure to per- and polyfluoroalkyl substances (PFAS) and their components with maternal glucose metabolism: A cross-sectional analysis in a birth cohort from Hong Kong by Yang, Aimin, Tam, Claudia H.T., Wong, Kwun Kiu, Ozaki, Risa, Lowe, William L., Metzger, Boyd E., Chow, Elaine, Tam, Wing Hung, Wong, Chris K.C., Ma, Ronald C.W.

“…Per- and polyfluoroalkyl substances (PFAS) are persistent chemicals that have been linked to increased risk of gestational diabetes mellitus (GDM) and may…”
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Pandemic-related barriers to the success of women in research: a framework for action by Davis, Pamela B., Meagher, Emma A., Pomeroy, Claire, Lowe, William L., Rubenstein, Arthur H., Wu, Joy Y., Curtis, Anne B., Jackson, Rebecca D.

“…Women in academia have fallen behind with publications and grant funding during the COVID-19 pandemic and risk dropping out of the research workforce…”
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Body Composition Measurements from Birth through 5 Years: Challenges, Gaps, and Existing & Emerging Technologies—A National Institutes of Health workshop by Gallagher, Dympna, Andres, Aline, Fields, David A., Evans, William J., Kuczmarski, Robert, Lowe, William L., Lumeng, Julie C., Oken, Emily, Shepherd, John A., Sun, Shumei, Heymsfield, Steven B.

“…Summary Body composition estimates are widely used in clinical research and field studies as measures of energy‐nutrient balance, functionality and health…”
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Metabolomics Reveals Broad-Scale Metabolic Perturbations in Hyperglycemic Mothers During Pregnancy by SCHOLTENS, Denise M, MUEHLBAUER, Michael J, DAYA, Natalie R, STEVENS, Robert D, DYER, Alan R, LOWE, Lynn P, METZGER, Boyd E, NEWGARD, Christopher B, BAIN, James R, LOWE, William L

“…OBJECTIVE To characterize metabolites across the range of maternal glucose by comparing metabolomic profiles of mothers with high and low fasting plasma…”
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Maternal BMI and Glycemia Impact the Fetal Metabolome by Lowe, Jr, William L, Bain, James R, Nodzenski, Michael, Reisetter, Anna C, Muehlbauer, Michael J, Stevens, Robert D, Ilkayeva, Olga R, Lowe, Lynn P, Metzger, Boyd E, Newgard, Christopher B, Scholtens, Denise M

“…We used targeted metabolomics to determine associations of maternal BMI and glucose levels with cord blood metabolites and associations of cord blood…”
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The short-chain fatty acid receptor, FFA2, contributes to gestational glucose homeostasis by Fuller, Miles, Priyadarshini, Medha, Gibbons, Sean M, Angueira, Anthony R, Brodsky, Michael, Hayes, M Geoffrey, Kovatcheva-Datchary, Petia, Bäckhed, Fredrik, Gilbert, Jack A, Lowe, Jr, William L, Layden, Brian T

“…The structure of the human gastrointestinal microbiota can change during pregnancy, which may influence gestational metabolism; however, a mechanism of action…”
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