Search Results - "Lowe, E. D"

Structural Studies on Phospho-CDK2/Cyclin A Bound to Nitrate, a Transition State Analogue:  Implications for the Protein Kinase Mechanism by Cook, A, Lowe, E. D, Chrysina, E. D, Skamnaki, V. T, Oikonomakos, N. G, Johnson, L. N

“…Eukaryotic protein kinases catalyze the phosphoryl transfer of the γ-phosphate of ATP to the serine, threonine, or tyrosine residue of protein substrates. The…”
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Catalytic Mechanism of Phosphorylase Kinase Probed by Mutational Studies by Skamnaki, V. T, Owen, D. J, Noble, M. E. M, Lowe, E. D, Lowe, G, Oikonomakos, N. G, Johnson, L. N

“…The contributions to catalysis of the conserved catalytic aspartate (Asp149) in the phosphorylase kinase catalytic subunit (PhK; residues 1−298) have been…”
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The crystal structure of a phosphorylase kinase peptide substrate complex: kinase substrate recognition by Lowe, E.D., Noble, M.E.M., Skamnaki, V.T., Oikonomakos, N.G., Owen, D.J., Johnson, L.N.

“…The structure of a truncated form of the γ‐subunit of phosphorylase kinase (PHKγt) has been solved in a ternary complex with a non‐hydrolysable ATP analogue…”
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The impact of floor type on lameness and hoof health of dairy origin bulls by Murphy, V. S., Lowe, D. E., Lively, F. O., Gordon, A. W.

“…This study aimed to evaluate the effect of using different floor types to accommodate growing and finishing beef cattle on lameness. In all, 80 dairy origin…”
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The effect of diet and covering fully slatted concrete floors with rubber strips on the intake, performance and cleanliness of dairy-origin bulls by Lowe, D. E., Lively, F. O., Gordon, A. W.

“…Fully slatted concrete floors are prevalent in beef cattle housing. However, concerns have been raised about welfare of cattle accommodated on slats. The…”
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Effect of overlaying rubber on fully slatted concrete floors on hoof health and lying postures in finishing dairy-origin bulls offered two contrasting diets by Lowe, D E, Gordon, A W, Lively, F O

“…Fully slatted concrete floors are labour-efficient, cost-effective and thus common in beef cattle housing. However, the welfare of cattle accommodated on them…”
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The effect of floor type on the performance, cleanliness, carcass characteristics and meat quality of dairy origin bulls by Murphy, V. S., Lowe, D. E., Lively, F. O., Gordon, A. W.

“…The aim of this study was to evaluate the effect of using different floor types to accommodate growing and finishing beef cattle on their performance,…”
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Laboratory-confirmed influenza-associated hospitalizations among children in the metropolitan Toronto and Peel region by active surveillance, 2004-2005 by Roberts, A, Bitnun, A, McGeer, A, Tran, D, Yau, Y, Simpson, K, Green, K, Lowe, D E, Kawa, B, Ford-Jones, E L

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Cloning and expression of Vibrio cholerae dsbA, a gene encoding a periplasmic protein disulphide isomerase by Lowe, E D, Freedman, R B, Hirst, T R, Barth, P T

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Crystal Structure of the Potassium Channel KirBac1.1 in the Closed State by Kuo, Anling, Gulbis, Jacqueline M., Antcliff, Jennifer F., Rahman, Tahmina, Lowe, Edward D., Zimmer, Jochen, Cuthbertson, Jonathan, Ashcroft, Frances M., Ezaki, Takayuki, Doyle, Declan A.

“…The KirBac1.1 channel belongs to the inward-rectifier family of potassium channels. Here we report the structure of the entire prokaryotic Kir channel…”
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A comparison of sires of Suffolk and Dutch Texel breeds and ewes of Greyface, Suffolk Cheviot and Dutch Texel breeds in terms of food intake, prolificacy and lamb growth rates by Johnston, S. D., Steen, R. W. J., Kilpatrick, D. J., Lowe, D. E., Chestnutt, D. M. B.

“…A comparison was made over 2 years of sires of Suffolk and Dutch Texel breeds and ewes of Greyface (Border Leicester × Scottish Blackface), Suffolk Cheviot and…”
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Dewatering makes big difference in compost strategies by LOWE, E. D, BUCKMASTER, D. R

“…Typically, 10 to 30 percent of the incoming raw materials in the food processing industry become waste rather than a value added product. Efficient,…”
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The crystal structure of the human polo-like kinase-1 polo box domain and its phospho-peptide complex by Cheng, Kin-Yip, Lowe, Edward D, Sinclair, John, Nigg, Erich A, Johnson, Louise N

“…Human polo‐like kinase Plk1 localizes to the centrosomes, kinetochores and central spindle structures during mitosis. It plays an essential role in promoting…”
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The Crystal Structure of Human CDK7 and Its Protein Recognition Properties by Lolli, Graziano, Lowe, Edward D., Brown, Nick R., Johnson, Louise N.

“…CDK7, a member of the cyclin-dependent protein kinase family, regulates the activities of other CDKs through phosphorylation on their activation segment and…”
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The structure of cyclin E1/CDK2: implications for CDK2 activation and CDK2-independent roles by Honda, Reiko, Lowe, Edward D, Dubinina, Elena, Skamnaki, Vicky, Cook, Atlanta, Brown, Nick R, Johnson, Louise N

“…Cyclin E, an activator of phospho‐CDK2 (pCDK2), is important for cell cycle progression in metazoans and is frequently overexpressed in cancer cells. It is…”
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The effects of floor type systems on the performance, cleanliness, carcass composition and meat quality of housed finishing beef cattle by Lowe, D.E., Steen, R.W.J., Beattie, V.E., Moss, B.W.

“…The objective of this experiment was to examine the effects of using different types of floors in accommodation for beef cattle on their performance,…”
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Divergence of Cofactor Recognition across Evolution: Coenzyme A Binding in a Prokaryotic Arylamine N-Acetyltransferase by Fullam, Elizabeth, Westwood, Isaac M., Anderton, Matthew C., Lowe, Edward D., Sim, Edith, Noble, Martin E.M.

“…Arylamine N-acetyltransferase (NAT) enzymes are widespread in nature. They serve to acetylate xenobiotics and/or endogenous substrates using acetyl coenzyme A…”
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The effect of improper normalization on the performance of an automated energy detector by STRUZINSKI, W. A, LOWE, E. D

“…This paper presents the results of a simulation experiment to determine the effect of improper normalization on the performance of an automated energy…”
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‘You have to push it—who's gonna raise your kids?’: situating child care and child care subsidy use in the daily routines of lower income families by Lowe, Edward D, Weisner, Thomas S

“…We use qualitative and quantitative data from a multi-year study of low-income families included in New Hope, an experimental anti-poverty intervention in…”
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Mechanism of Lys48-linked polyubiquitin chain recognition by the Mud1 UBA domain by Trempe, Jean-François, Brown, Nicholas R, Lowe, Edward D, Gordon, Colin, Campbell, Iain D, Noble, Martin EM, Endicott, Jane A

“…The ubiquitin‐pathway associated (UBA) domain is a 40‐residue polyubiquitin‐binding motif. The Schizosaccharomyces pombe protein Mud1 is an ortholog of the…”
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