Search Results - "Lowe, Anson W."

The pancreatic stellate cell: a star on the rise in pancreatic diseases by Omary, M Bishr, Lugea, Aurelia, Lowe, Anson W, Pandol, Stephen J

“…Pancreatic stellate cells (PaSCs) are myofibroblast-like cells found in the areas of the pancreas that have exocrine function. PaSCs are regulated by autocrine…”
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The Adenocarcinoma-Associated Antigen, AGR2, Promotes Tumor Growth, Cell Migration, and Cellular Transformation by ZHENG WANG, YING HAO, LOWE, Anson W

“…The AGR2 gene encodes a secretory protein that is highly expressed in adenocarcinomas of the esophagus, pancreas, breast, and prostate. This study explores the…”
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Uptake through glycoprotein 2 of FimH + bacteria by M cells initiates mucosal immune response by Yabashi, Atsuko, Kiyono, Hiroshi, Tobe, Toru, Kawano, Sayaka, Hamura, Kimiyo, Ohno, Hiroshi, Kadokura, Kazunori, Kimura, Shunsuke, Nakato, Gaku, Murakami, Takaya, Fukuda, Shinji, Pontes, Gemilson Soares, Kawano, Kazuya, Fukuoka, Shin-Ichi, Lowe, Anson W, Nochi, Tomonori, Ebisawa, Masashi, Hase, Koji, Fujimura, Yumiko, Waguri, Satoshi, Iimura, Mitsutoshi, Itoh, Kikuji

“…The mucosal immune system forms the largest part of the entire immune system, containing about three-quarters of all lymphocytes and producing grams of…”
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Detection of colonic dysplasia in vivo using a targeted heptapeptide and confocal microendoscopy by Wang, Thomas D, Hsiung, Pei-Lin, Hardy, Jonathan, Friedland, Shai, Soetikno, Roy, Du, Christine B, Wu, Amy P, Sahbaie, Peyman, Crawford, James M, Lowe, Anson W, Contag, Christopher H

“…A combination of targeted probes and new imaging technologies provides a powerful set of tools with the potential to improve the early detection of cancer. To…”
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The Human Adenocarcinoma-associated Gene, AGR2, Induces Expression of Amphiregulin through Hippo Pathway Co-activator YAP1 Activation by Dong, Aiwen, Gupta, Aparna, Pai, Reetesh K., Tun, May, Lowe, Anson W.

“…Anterior Gradient Homolog 2 (AGR2) is expressed by the normal intestine and by most human adenocarcinomas, including those derived from the esophagus,…”
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Inducible expression of immediate early genes is regulated through dynamic chromatin association by NF45/ILF2 and NF90/NF110/ILF3 by Wu, Ting-Hsuan, Shi, Lingfang, Lowe, Anson W, Nicolls, Mark R, Kao, Peter N

“…Immediate early gene (IEG) transcription is rapidly activated by diverse stimuli. This transcriptional regulation is assumed to involve constitutively…”
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Immunohistochemical panel for distinguishing esophageal adenocarcinoma from squamous cell carcinoma: a combination of p63, cytokeratin 5/6, MUC5AC, and anterior gradient homolog 2 allows optimal subtyping by DiMaio, Michael A., MD, Kwok, Shirley, BSc, Montgomery, Kelli D., BSc, Lowe, Anson W., MD, Pai, Reetesh K., MD

“…Summary Distinguishing adenocarcinoma and squamous cell carcinoma of the esophagus is often based on morphological criteria and can be difficult in small…”
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Comprehensive Gene Expression Profiling of Peyer's Patch M Cells, Villous M-Like Cells, and Intestinal Epithelial Cells by Terahara, Kazutaka, Yoshida, Masato, Igarashi, Osamu, Nochi, Tomonori, Pontes, Gemilson Soares, Hase, Koji, Ohno, Hiroshi, Kurokawa, Shiho, Mejima, Mio, Takayama, Naoko, Yuki, Yoshikazu, Lowe, Anson W, Kiyono, Hiroshi

“…Separate populations of M cells have been detected in the follicle-associated epithelium of Peyer's patches (PPs) and the villous epithelium of the small…”
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Anterior Gradient 2 (AGR2) Induced Epidermal Growth Factor Receptor (EGFR) Signaling Is Essential for Murine Pancreatitis-Associated Tissue Regeneration by Wodziak, Dariusz, Dong, Aiwen, Basin, Michael F, Lowe, Anson W

“…A recently published study identified Anterior Gradient 2 (AGR2) as a regulator of EGFR signaling by promoting receptor presentation from the endoplasmic…”
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Metabolomic-derived novel cyst fluid biomarkers for pancreatic cysts: glucose and kynurenine by Park, Walter G., MD, Wu, Manhong, PhD, Bowen, Raffick, PhD, Zheng, Ming, PhD, Fitch, William L., PhD, Pai, Reetesh K., MD, Wodziak, Dariusz, BS, Visser, Brendan C., MD, Poultsides, George A., MD, Norton, Jeff A., MD, PhD, Banerjee, Subhas, MD, Chen, Ann M., MD, Friedland, Shai, MD, Scott, Brennan A., MD, Pasricha, Pankaj Jay, MD, Lowe, Anson W., MD, Peltz, Gary, MD, PhD

“…Background Better pancreatic cyst fluid biomarkers are needed. Objective To determine whether metabolomic profiling of pancreatic cyst fluid would yield…”
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Loss of Anterior Gradient 2 (Agr2) Expression Results in Hyperplasia and Defective Lineage Maturation in the Murine Stomach by Gupta, Aparna, Wodziak, Dariusz, Tun, May, Bouley, Donna M., Lowe, Anson W.

“…Recent studies of epithelial tissues have revealed the presence of tissue-specific stem cells that are able to establish multiple cell lineages within an…”
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The pancreatic zymogen granule membrane protein, GP2, binds Escherichia coli Type 1 fimbriae by Yu, Su, Lowe, Anson W

“…GP2 is the major membrane protein present in the pancreatic zymogen granule, and is cleaved and released into the pancreatic duct along with exocrine…”
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Exploration of Global Gene Expression Patterns in Pancreatic Adenocarcinoma Using cDNA Microarrays by Iacobuzio-Donahue, Christine A., Maitra, Anirban, Olsen, Mari, Lowe, Anson W., Van Heek, N. Tjarda, Rosty, Christophe, Walter, Kim, Sato, Norihiro, Parker, Antony, Ashfaq, Raheela, Jaffee, Elizabeth, Ryu, Byungwoo, Jones, Jessa, Eshleman, James R., Yeo, Charles J., Cameron, John L., Kern, Scott E., Hruban, Ralph H., Brown, Patrick O., Goggins, Michael

“…Pancreatic cancer is the fifth leading cause of cancer death in the United States. We used cDNA microarrays to analyze global gene expression patterns in 14…”
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Gene expression patterns in pancreatic tumors, cells and tissues by Lowe, Anson W, Olsen, Mari, Hao, Ying, Lee, Sum P, Taek Lee, Kyu, Chen, Xin, van de Rijn, Matt, Brown, Patrick O

“…Cancers of the pancreas originate from both the endocrine and exocrine elements of the organ, and represent a major cause of cancer-related death. This study…”
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The nucleotide binding motif of hepatitis C virus NS4B can mediate cellular transformation and tumor formation without Ha‐ras co‐transfection by Einav, Shirit, Sklan, Ella H., Moon, Hyang Mi, Gehrig, Elizabeth, Liu, Ping, Hao, Ying, Lowe, Anson W., Glenn, Jeffrey S.

“…Hepatitis C virus (HCV) is an important cause of chronic liver disease and is complicated by hepatocellular carcinoma (HCC). Mechanisms whereby the virus…”
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Epidermal Growth Factor Receptor (EGFR) Signaling Requires a Specific Endoplasmic Reticulum Thioredoxin for the Post-translational Control of Receptor Presentation to the Cell Surface by Dong, Aiwen, Wodziak, Dariusz, Lowe, Anson W.

“…The epidermal growth factor receptor (EGFR) is a well characterized receptor-tyrosine kinase that functions in development and serves a vital role in many…”
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AGR2 Gene Function Requires a Unique Endoplasmic Reticulum Localization Motif by Gupta, Aparna, Dong, Aiwen, Lowe, Anson W.

“…Soluble proteins are enriched in the endoplasmic reticulum (ER) by retrograde transport from the Golgi that is mediated by the KDEL receptors. In addition to…”
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Mistaken identity of widely used esophageal adenocarcinoma cell line TE-7 by BOONSTRA, Jurjen J, VAN DER VELDEN, Albertina W, BEVERLOO, Berna H, VAN DEKKEN, Herman, TILANUS, Hugo W, DINJENS, Winand N. M, BEERENS, Erwin C. W, VAN MARION, Ronald, MORITA-FUJIMURA, Yuiko, MATSUI, Yasuhisa, NISHIHIRA, Tetsuro, TSELEPIS, Chris, HAINAUT, Pierre, LOWE, Anson W

“…Cancer of the esophagus is the seventh leading cause of cancer death worldwide. Esophageal carcinoma cell lines are useful models to study the biological and…”
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Absence of the Major Zymogen Granule Membrane Protein, GP2, Does Not Affect Pancreatic Morphology or Secretion by Yu, Su, Michie, Sara A., Lowe, Anson W.

“…The majority of digestive enzymes in humans are produced in the pancreas where they are stored in zymogen granules before secretion into the intestine. GP2 is…”
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Detection of Pancreatic Ductal Adenocarcinoma in Mice by Ultrasound Imaging of Thymocyte Differentiation Antigen 1 by Foygel, Kira, Wang, Huaijun, Machtaler, Steven, Lutz, Amelie M, Chen, Ru, Pysz, Marybeth, Lowe, Anson W, Tian, Lu, Carrigan, Tricia, Brentnall, Teresa A, Willmann, Jürgen K

“…Background & Aims Early detection of pancreatic ductal adenocarcinoma (PDAC) allows for surgical resection and increases patient survival times. Imaging agents…”
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