Search Results - "Low, J M"

The dopamine D4 receptor is essential for hyperactivity and impaired behavioral inhibition in a mouse model of attention deficit hyperactivity disorder by AVALE, M. E, FALZONE, T. L, GELMAN, D. M, LOW, M. J, GRANDY, D. K, RUBINSTEIN, M

“…The dopamine D4 receptor (D4R) is a candidate gene for attention deficit/hyperactivity disorder (ADHD) based on genetic studies reporting that particular…”
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Hypothalamic‐specific proopiomelanocortin deficiency reduces alcohol drinking in male and female mice by Zhou, Y., Rubinstein, M., Low, M. J., Kreek, M. J.

“…Opioid receptor antagonist naltrexone reduces alcohol consumption and relapse in both humans and rodents. This study investigated whether hypothalamic…”
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Constitutive TLR4 signalling in intestinal epithelium reduces tumor load by increasing apoptosis in APC(Min/+) mice by Li, Y, Teo, W L, Low, M J, Meijer, L, Sanderson, I, Pettersson, S, Greicius, G

“…The microbial pattern-recognizing Toll-like receptors (TLRs) are major signal transducers known to shape and influence the postnatal maturation of host…”
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Role of dopamine D1‐like receptors in methamphetamine locomotor responses of D2 receptor knockout mice by Kelly, M. A., Low, M. J., Rubinstein, M., Phillips, T. J.

“…Behavioral sensitization to psychostimulants manifests as an increased locomotor response with repeated administration. Dopamine systems are accepted to play a…”
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Increased Pituitary Vascular Endothelial Growth Factor-A in Dopaminergic D2 Receptor Knockout Female Mice by Cristina, C, Díaz-Torga, G, Baldi, A, Góngora, A, Rubinstein, M, Low, M. J, Becú-Villalobos, D

“…Vascular endothelial growth factor (VEGF)-A is an important angiogenic cytokine in cancer and pathological angiogenesis and has been related to the…”
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The absence of endogenous β-endorphin selectively blocks phosphorylation and desensitization of mu opioid receptors following partial sciatic nerve ligation by Petraschka, M, Li, S, Gilbert, T.L, Westenbroek, R.E, Bruchas, M.R, Schreiber, S, Lowe, J, Low, M.J, Pintar, J.E, Chavkin, C

“…Abstract Phosphorylation of specific sites in the second intracellular loop and in the C-terminal domain have previously been suggested to cause…”
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Measurement of biomarkers in juvenile idiopathic arthritis patients and their significant association with disease severity : a comparative study by GILLIAM, B. E, CHAUHAN, A. K, LOW, J. M, MOORE, T. L

“…To evaluate in juvenile idiopathic arthritis (JIA) patients a biomarker panel of anti-cyclic citrullinated peptide (anti-CCP) antibodies, cartilage oligomeric…”
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Facilitated Glutamatergic Transmission in the Striatum of D2 Dopamine Receptor-Deficient Mice by Cepeda, C, Hurst, R. S, Altemus, K. L, Flores-Hernandez, J, Calvert, C. R, Jokel, E. S, Grandy, D. K, Low, M. J, Rubinstein, M, Ariano, M. A, Levine, M. S

“…  1 Mental Retardation Research Center, University of California, Los Angeles, California 90095;   2 Department of Cell and Developmental Biology and   3…”
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The contribution of endogenous opioids to food reward is dependent on sex and background strain by Hayward, M.D, Low, M.J

“…Abstract Complex behaviors such as those associated with reward to unconditioned positive reinforcers are polygenic processes. In studies using genetically…”
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Lipocalin 2 performs contrasting, location-dependent roles in APCmin tumor initiation and progression by Reilly, P T, Teo, W L, Low, M J, Amoyo-Brion, A A, Dominguez-Brauer, C, Elia, A J, Berger, T, Greicius, G, Pettersson, S, Mak, T W

“…Evidence that lipocalin 2 (LCN2) is oncogenic has grown in recent years and comes from both animal models and expression analysis from a variety of human…”
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In situ hybridization analysis of anterior pituitary hormone gene expression during fetal mouse development by Japon, MA, Rubinstein, M, Low, MJ

“…We used 35S-labeled oligonucleotides and cRNAs (riboprobes) to detect the temporal order and spatial pattern of anterior pituitary hormone gene expression in…”
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Disruption of the D2 Dopamine Receptor Alters GH and IGF-I Secretion and Causes Dwarfism in Male Mice by Díaz-Torga, G, Feierstein, C, Libertun, C, Gelman, D, Kelly, M. A, Low, M. J, Rubinstein, M, Becú-Villalobos, D

“…We determined the consequences of the loss of D2 receptors (D2R) on the GH-IGF-I axis using mice deficient in functional dopamine D2 receptors by targeted…”
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Brain stimulation and morphine reward deficits in dopamine D2 receptor-deficient mice by ELMER, G. I, PIEPER, J. O, LEVY, J, RUBINSTEIN, M, LOW, M. J, GRANDY, D. K, WISE, R. A

“…The rewarding effects of lateral hypothalamic brain stimulation, various natural rewards, and several drugs of abuse are attenuated by D1 or D2 dopamine…”
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Identification of a Receptor for γ Melanotropin and Other Proopiomelanocortin Peptides in the Hypothalamus and Limbic System by ROSELLI-REHFUSS, L, MOUNTJOY, K. G, ROBBINS, L. S, MORTRUD, M. T, LOW, M. J, TATRO, J. B, ENTWISTLE, M. L, SIMERLY, R. B, CONE, R. D

“…Corticotropin (ACTH) and melanotropin (MSH) peptides (melanocortins) are produced not only in the pituitary but also in the brain, with highest concentrations…”
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Knowledge, attitudes, practices, and perceived challenges for healthcare workers on waterless intensive care unit (ICU) care at a neonatal ICU in Singapore by Buvaneswarran, S., Chua, M.C.W., Amin, Z., Wang, X., Low, J.M.

“…Implementation of waterless care, including removal of sinks from patient care areas, is an emerging approach to reduce waterborne infections in high-risk…”
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The impact of sink removal and other water-free interventions in intensive care units on water-borne healthcare-associated infections: a systematic review by Low, J.M., Chan, M., Low, J.L., Chua, M.C.W., Lee, J.H.

“…With increasing awareness of water sinks as potential sources of outbreaks and transmission of multi-drug resistant (MDR) bacteria in intensive care units…”
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The arcuate nucleus as a conduit for diverse signals relevant to energy homeostasis by Cone, RD, Cowley, MA, Butler, AA, Fan, W, Marks, DL, Low, MJ

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Somatostatin is required for masculinization of growth hormone-regulated hepatic gene expression but not of somatic growth by Low, M J, Otero-Corchon, V, Parlow, A F, Ramirez, J L, Kumar, U, Patel, Y C, Rubinstein, M

“…Pulsatile growth hormone (GH) secretion differs between males and females and regulates the sex-specific expression of cytochrome P450s in liver. Sex steroids…”
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A role for the complement system in rheumatoid arthritis by Low, J M, Moore, T L

“…The production of autoreactive antibodies from self-reactive B cells results in the formation of immune complexes that deposit in tissue and fix complement,…”
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Absence of Opioid Stress-Induced Analgesia in Mice Lacking β -Endorphin by Site-Directed Mutagenesis by Rubinstein, Marcelo, Mogil, Jeffrey S., Japón, Miguel, Chan, E. Cheng, Allen, Richard G., Low, Malcolm J.

“…A physiological role for β -endorphin in endogenous pain inhibition was investigated by targeted mutagenesis of the proopiomelanocortin gene in mouse embryonic…”
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