Search Results - "Lovell, Jonathan F."

Advanced Functional Nanomaterials for Theranostics by Huang, Haoyuan, Lovell, Jonathan F.

“…Nanoscale materials have been explored extensively as agents for therapeutic and diagnostic (i.e., theranostic) applications. Research efforts have shifted…”
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Metalloporphyrin nanoparticles: Coordinating diverse theranostic functions by Shao, Shuai, Rajendiran, Venugopal, Lovell, Jonathan F.

“…[Display omitted] •Metalloporphyrin nanoparticles have been described for a range of bio-applications.•Metal-chelation can functionalize porphyrin…”
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Recent applications of phthalocyanines and naphthalocyanines for imaging and therapy by Zhang, Yumiao, Lovell, Jonathan F.

“…With high extinction coefficients and long absorption wavelengths in the near infrared region, phthalocyanines (Pcs) and naphthalocyanines (Ncs) are…”
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Chemophototherapy: An Emerging Treatment Option for Solid Tumors by Luo, Dandan, Carter, Kevin A., Miranda, Dyego, Lovell, Jonathan F.

“…Near infrared (NIR) light penetrates human tissues with limited depth, thereby providing a method to safely deliver non‐ionizing radiation to well‐defined…”
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Programmable Real-time Clinical Photoacoustic and Ultrasound Imaging System by Kim, Jeesu, Park, Sara, Jung, Yuhan, Chang, Sunyeob, Park, Jinyong, Zhang, Yumiao, Lovell, Jonathan F., Kim, Chulhong

“…Photoacoustic imaging has attracted interest for its capacity to capture functional spectral information with high spatial and temporal resolution in…”
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Lipoprotein-Inspired Nanoparticles for Cancer Theranostics by Ng, Kenneth K, Lovell, Jonathan F, Zheng, Gang

“…Over hundreds of millions of years, animals have evolved endogenous lipoprotein nanoparticles for shuttling hydrophobic molecules to different parts of the…”
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Inhibition of SARS-CoV-2 viral entry upon blocking N- and O-glycan elaboration by Yang, Qi, Hughes, Thomas A, Kelkar, Anju, Yu, Xinheng, Cheng, Kai, Park, Sheldon, Huang, Wei-Chiao, Lovell, Jonathan F, Neelamegham, Sriram

“…The Spike protein of SARS-CoV-2, its receptor-binding domain (RBD), and its primary receptor ACE2 are extensively glycosylated. The impact of this…”
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Stimulus-Responsive Nanomedicines for Disease Diagnosis and Treatment by Liu, Gengqi, Lovell, Jonathan F, Zhang, Lei, Zhang, Yumiao

“…Stimulus-responsive drug delivery systems generally aim to release the active pharmaceutical ingredient (API) in response to specific conditions and have…”
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Surfactant‐Stripped Micelles for NIR‐II Photoacoustic Imaging through 12 cm of Breast Tissue and Whole Human Breasts by Chitgupi, Upendra, Nyayapathi, Nikhila, Kim, Jeesu, Wang, Depeng, Sun, Boyang, Li, Changning, Carter, Kevin, Huang, Wei‐Chiao, Kim, Chulhong, Xia, Jun, Lovell, Jonathan F.

“…Surfactant‐stripped micelles are formed from a commercially available cyanine fluoroalkylphosphate (CyFaP) salt dye and used for high contrast photoacoustic…”
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Dual-color photoacoustic lymph node imaging using nanoformulated naphthalocyanines by Lee, Changho, Kim, Jeesu, Zhang, Yumiao, Jeon, Mansik, Liu, Chengbo, Song, Liang, Lovell, Jonathan F, Kim, Chulhong

“…Abstract Demarking lymph node networks is important for cancer staging in clinical practice. Here, we demonstrate in vivo dual-color photoacoustic…”
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Porphyrins as theranostic agents from prehistoric to modern times by Zhang, Yumiao, Lovell, Jonathan F

“…Long before humans roamed the planet, porphyrins in blood were serving not only as indispensable oxygen carriers, but also as the bright red contrast agent…”
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Porphyrin–phospholipid liposomes permeabilized by near-infrared light by Carter, Kevin A., Shao, Shuai, Hoopes, Matthew I., Luo, Dandan, Ahsan, Bilal, Grigoryants, Vladimir M., Song, Wentao, Huang, Haoyuan, Zhang, Guojian, Pandey, Ravindra K., Geng, Jumin, Pfeifer, Blaine A., Scholes, Charles P., Ortega, Joaquin, Karttunen, Mikko, Lovell, Jonathan F.

“…The delivery of therapeutic compounds to target tissues is a central challenge in treating disease. Externally controlled drug release systems hold potential…”
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Opportunities for Photoacoustic-Guided Drug Delivery by Xia, Jun, Kim, Chulhong, Lovell, Jonathan F

“…Photoacoustic imaging (PAI) is rapidly becoming established as a viable imaging modality for small animal research, with promise of near-future human clinical…”
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Role of nanoparticle-mediated immunogenic cell death in cancer immunotherapy by Sun, Yajie, Feng, Xiangru, Wan, Chao, Lovell, Jonathan F., Jin, Honglin, Ding, Jianxun

“…Cancer immunotherapy, which suppresses cancer progression by activating the anti-cancer immunity of patients, shows utility in treating multiple types of…”
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Ingestible Contrast Agents for Gastrointestinal Imaging by Yang, Xingyue, Lovell, Jonathan F., Zhang, Yumiao

“…Gastrointestinal (GI) ailments cover a wide variety of diseases involving the esophagus, stomach, small intestine, large intestine, and rectum. They bring…”
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Rapid Light-Triggered Drug Release in Liposomes Containing Small Amounts of Unsaturated and Porphyrin-Phospholipids by Luo, Dandan, Li, Nasi, Carter, Kevin A., Lin, Cuiyan, Geng, Jumin, Shao, Shuai, Huang, Wei-Chiao, Qin, Yueling, Atilla-Gokcumen, G. Ekin, Lovell, Jonathan F.

“…Prompt membrane permeabilization is a requisite for liposomes designed for local stimuli‐induced intravascular release of therapeutic payloads. Incorporation…”
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Therapeutic surfactant-stripped frozen micelles by Zhang, Yumiao, Song, Wentao, Geng, Jumin, Chitgupi, Upendra, Unsal, Hande, Federizon, Jasmin, Rzayev, Javid, Sukumaran, Dinesh K., Alexandridis, Paschalis, Lovell, Jonathan F.

“…Injectable hydrophobic drugs are typically dissolved in surfactants and non-aqueous solvents which can induce negative side-effects. Alternatives like…”
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Membrane Binding by tBid Initiates an Ordered Series of Events Culminating in Membrane Permeabilization by Bax by Lovell, Jonathan F., Billen, Lieven P., Bindner, Scott, Shamas-Din, Aisha, Fradin, Cecile, Leber, Brian, Andrews, David W.

“…In normal circumstances, the Bcl-2 family dutifully governs when cells die. However, the rules of engagement between the pro- and antiapoptotic family members…”
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Biomimetic Liposomal Nanoplatinum for Targeted Cancer Chemophototherapy by Liu, Xue‐Liang, Dong, Xiao, Yang, Si‐Cong, Lai, Xing, Liu, Hai‐Jun, Gao, Yuhao, Feng, Hai‐Yi, Zhu, Mao‐Hua, Yuan, Yihang, Lu, Qin, Lovell, Jonathan F., Chen, Hong‐Zhuan, Fang, Chao

“…Photodynamic therapy (PDT) of cancer is limited by tumor hypoxia. Platinum nanoparticles (nano‐Pt) as a catalase‐like nanoenzyme can enhance PDT through…”
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Self-adjuvanting cancer nanovaccines by Liao, Zhiyun, Huang, Jing, Lo, Pui-Chi, Lovell, Jonathan F, Jin, Honglin, Yang, Kunyu

“…Abstract Nanovaccines, a new generation of vaccines that use nanoparticles as carriers and/or adjuvants, have been widely used in the prevention and treatment…”
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