Search Results - "Lovell, Claudia D."
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Compartmentalised acyl-CoA metabolism and roles in chromatin regulation
Published in Molecular metabolism (Germany) (01-08-2020)“…Many metabolites serve as important signalling molecules to adjust cellular activities and functions based on nutrient availability. Links between acetyl-CoA…”
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Control of embryonic stem cell identity by BRD4-dependent transcriptional elongation of super-enhancer-associated pluripotency genes
Published in Cell reports (Cambridge) (09-10-2014)“…Transcription factors and chromatin-remodeling complexes are key determinants of embryonic stem cell (ESC) identity. Here, we demonstrate that BRD4, a member…”
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3
An epigenetic switch controls an alternative NR2F2 isoform that unleashes a metastatic program in melanoma
Published in Nature communications (04-04-2023)“…Metastatic melanoma develops once transformed melanocytic cells begin to de-differentiate into migratory and invasive melanoma cells with neural crest cell…”
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Long Noncoding RNAs That Function in Nutrition: Lnc-ing Nutritional Cues to Metabolic Pathways
Published in Annual review of nutrition (22-08-2022)“…Long noncoding RNAs (lncRNAs) are sensitive to changing environments and play key roles in health and disease. Emerging evidence indicates that lncRNAs…”
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5
The conneXion between sex and immune responses
Published in Nature reviews. Immunology (01-07-2024)“…There are notable sex-based differences in immune responses to pathogens and self-antigens, with female individuals exhibiting increased susceptibility to…”
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Quantitative subcellular acyl-CoA analysis reveals distinct nuclear metabolism and isoleucine-dependent histone propionylation
Published in Molecular cell (20-01-2022)“…Quantitative subcellular metabolomic measurements can explain the roles of metabolites in cellular processes but are subject to multiple confounding factors…”
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The X-quisite X-ception: Sex Differences with Immune Responses
Published in Nature reviews. Immunology (21-02-2024)“…There are significant sex-based differences in immune responses to pathogens and self-antigens, with human females exhibiting increased susceptibility to…”
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