Search Results - "Lovell, Claudia D"

Compartmentalised acyl-CoA metabolism and roles in chromatin regulation by Trefely, Sophie, Lovell, Claudia D., Snyder, Nathaniel W., Wellen, Kathryn E.

“…Many metabolites serve as important signalling molecules to adjust cellular activities and functions based on nutrient availability. Links between acetyl-CoA…”
Get full text

Control of embryonic stem cell identity by BRD4-dependent transcriptional elongation of super-enhancer-associated pluripotency genes by Di Micco, Raffaella, Fontanals-Cirera, Barbara, Low, Vivien, Ntziachristos, Panagiotis, Yuen, Stephanie K, Lovell, Claudia D, Dolgalev, Igor, Yonekubo, Yoshiya, Zhang, Guangtao, Rusinova, Elena, Gerona-Navarro, Guillermo, Cañamero, Marta, Ohlmeyer, Michael, Aifantis, Iannis, Zhou, Ming-Ming, Tsirigos, Aristotelis, Hernando, Eva

“…Transcription factors and chromatin-remodeling complexes are key determinants of embryonic stem cell (ESC) identity. Here, we demonstrate that BRD4, a member…”
Get full text

An epigenetic switch controls an alternative NR2F2 isoform that unleashes a metastatic program in melanoma by Davalos, Veronica, Lovell, Claudia D., Von Itter, Richard, Dolgalev, Igor, Agrawal, Praveen, Baptiste, Gillian, Kahler, David J., Sokolova, Elena, Moran, Sebastian, Piqué, Laia, Vega-Saenz de Miera, Eleazar, Fontanals-Cirera, Barbara, Karz, Alcida, Tsirigos, Aristotelis, Yun, Chi, Darvishian, Farbod, Etchevers, Heather C., Osman, Iman, Esteller, Manel, Schober, Markus, Hernando, Eva

“…Metastatic melanoma develops once transformed melanocytic cells begin to de-differentiate into migratory and invasive melanoma cells with neural crest cell…”
Get full text

Long Noncoding RNAs That Function in Nutrition: Lnc-ing Nutritional Cues to Metabolic Pathways by Lovell, Claudia D, Anguera, Montserrat C

“…Long noncoding RNAs (lncRNAs) are sensitive to changing environments and play key roles in health and disease. Emerging evidence indicates that lncRNAs…”
Get full text

The conneXion between sex and immune responses by Forsyth, Katherine S., Jiwrajka, Nikhil, Lovell, Claudia D., Toothacre, Natalie E., Anguera, Montserrat C.

“…There are notable sex-based differences in immune responses to pathogens and self-antigens, with female individuals exhibiting increased susceptibility to…”
Get full text

Quantitative subcellular acyl-CoA analysis reveals distinct nuclear metabolism and isoleucine-dependent histone propionylation by Trefely, Sophie, Huber, Katharina, Liu, Joyce, Noji, Michael, Stransky, Stephanie, Singh, Jay, Doan, Mary T., Lovell, Claudia D., von Krusenstiern, Eliana, Jiang, Helen, Bostwick, Anna, Pepper, Hannah L., Izzo, Luke, Zhao, Steven, Xu, Jimmy P., Bedi, Kenneth C., Rame, J. Eduardo, Bogner-Strauss, Juliane G., Mesaros, Clementina, Sidoli, Simone, Wellen, Kathryn E., Snyder, Nathaniel W.

“…Quantitative subcellular metabolomic measurements can explain the roles of metabolites in cellular processes but are subject to multiple confounding factors…”
Get full text

The X-quisite X-ception: Sex Differences with Immune Responses by Forsyth, Katherine S., Jiwrajka, Nikhil, Lovell, Claudia D., Toothacre, Natalie E., Anguera, Montserrat C.

“…There are significant sex-based differences in immune responses to pathogens and self-antigens, with human females exhibiting increased susceptibility to…”
Get full text