Search Results - "Lovasz, Kristine D."

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    Use of Medium-Sized Cycloalkyl Rings To Enhance Secondary Binding: Discovery of a New Class of Human Immunodeficiency Virus (HIV) Protease Inhibitors by Romines, Karen R, Watenpaugh, Keith D, Tomich, Paul K, Howe, W. Jeffrey, Morris, Jeanette K, Lovasz, Kristine D, Mulichak, Anne M, Finzel, Barry C, Lynn, Janet C

    Published in Journal of medicinal chemistry (01-05-1995)
    “…A unique strategy for the enhancement of secondary binding of an inhibitor to an enzyme has been demonstrated in the design of new human immunodeficiency virus…”
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    Structure-Based Design of Nonpeptidic HIV Protease Inhibitors from a Cyclooctylpyranone Lead Structure by Romines, Karen R, Watenpaugh, Keith D, Howe, W. Jeffrey, Tomich, Paul K, Lovasz, Kristine D, Morris, Jeanette K, Janakiraman, Musiri N, Lynn, Janet C, Horng, Miao-Miao

    Published in Journal of medicinal chemistry (01-10-1995)
    “…Recently, the novel cyclooctylpyranone HIV protease inhibitor 1 was identified in our labs, and an X-ray structure of this inhibitor complexed with HIV-2…”
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    Synthesis and antibacterial activity of [6,5,5] and [6,6,5] tricyclic fused oxazolidinones by Gleave, D.Mark, Brickner, Steven J., Manninen, Peter R., Allwine, Debra A., Lovasz, Kristine D., Rohrer, Douglas C., Tucker, John A., Zurenko, Gary E., Ford, Charles W.

    Published in Bioorganic & medicinal chemistry letters (19-05-1998)
    “…A series of conformationally restricted, [6,5,5] and [6,6,5] tricyclic fused oxazolidinones were synthesized and tested for antibacterial activity. Several…”
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