Search Results - "Louwen, R."

MS2Query: reliable and scalable MS2 mass spectra-based analogue search by de Jonge, Niek F., Louwen, Joris J. R., Chekmeneva, Elena, Camuzeaux, Stephane, Vermeir, Femke J., Jansen, Robert S., Huber, Florian, van der Hooft, Justin J. J.

“…Metabolomics-driven discoveries of biological samples remain hampered by the grand challenge of metabolite annotation and identification. Only few metabolites…”
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iPRESTO: Automated discovery of biosynthetic sub-clusters linked to specific natural product substructures by Louwen, Joris J R, Kautsar, Satria A, van der Burg, Sven, Medema, Marnix H, van der Hooft, Justin J J

“…Microbial specialised metabolism is full of valuable natural products that are applied clinically, agriculturally, and industrially. The genes that encode…”
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Enhanced correlation-based linking of biosynthetic gene clusters to their metabolic products through chemical class matching by Louwen, Joris J R, Medema, Marnix H, van der Hooft, Justin J J

“…It is well-known that the microbiome produces a myriad of specialised metabolites with diverse functions. To better characterise their structures and identify…”
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Comprehensive Large-Scale Integrative Analysis of Omics Data To Accelerate Specialized Metabolite Discovery by Louwen, Joris J R, van der Hooft, Justin J J

“…Microbial specialized metabolites are key mediators in host-microbiome interactions. Most of the chemical space produced by the microbiome currently remains…”
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Lack of Association between the Presence of the pVir Plasmid and Bloody Diarrhea in Campylobacter jejuni Enteritis by Louwen, R.P.L, Belkum, A. van, Wagenaar, J.A, Doorduyn, Y, Achterberg, R, Endtz, H.P

“…The main mechanisms by which Campylobacter jejuni causes diarrhea are unknown. In contrast to a recent communication, we report here the absence of an…”
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Good practices and recommendations for using and benchmarking computational metabolomics metabolite annotation tools by de Jonge, Niek F., Mildau, Kevin, Meijer, David, Louwen, Joris J. R., Bueschl, Christoph, Huber, Florian, van der Hooft, Justin J. J.

“…Background Untargeted metabolomics approaches based on mass spectrometry obtain comprehensive profiles of complex biological samples. However, on average only…”
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Campylobacter bacteremia: a rare and under-reported event? by Louwen, R, van Baarlen, P, van Vliet, A H M, van Belkum, A, Hays, J P, Endtz, H P

“…Bacteria belonging to the species Campylobacter are the most common cause of bacterial diarrhoea in humans. The clinical phenotype associated with…”
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Comprehensive Large-Scale Integrative Analysis of Omics Data To Accelerate Specialized Metabolite Discovery by Louwen, Joris J. R., van der Hooft, Justin J. J.

“…Microbial specialized metabolites are key mediators in host-microbiome interactions. Most of the chemical space produced by the microbiome currently remains…”
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Can Campylobacter coli induce Guillain-Barré syndrome? by van Belkum, A, Jacobs, B, van Beek, E, Louwen, R, van Rijs, W, Debruyne, L, Gilbert, M, Li, J, Jansz, A, Mégraud, F, Endtz, H

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The role of CRISPR-Cas systems in virulence of pathogenic bacteria by Louwen, Rogier, Staals, Raymond H J, Endtz, Hubert P, van Baarlen, Peter, van der Oost, John

“…Clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated (Cas) genes are present in many bacterial and archaeal genomes. Since…”
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Are bacteriophage defence and virulence two sides of the same coin in Campylobacter jejuni? by Louwen, Rogier, van Baarlen, Peter

“…The continuous battle for survival in the environment has led to the development or acquisition of sophisticated defence systems in bacteria. These defence…”
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A novel link between Campylobacter jejuni bacteriophage defence, virulence and Guillain–Barré syndrome by Louwen, R., Horst-Kreft, D., de Boer, A. G., van der Graaf, L., de Knegt, G., Hamersma, M., Heikema, A. P., Timms, A. R., Jacobs, B. C., Wagenaar, J. A., Endtz, H. P., van der Oost, J., Wells, J. M., Nieuwenhuis, E. E. S., van Vliet, A. H. M., Willemsen, P. T. J., van Baarlen, P., van Belkum, A.

“…Guillain–Barré syndrome (GBS) is a post-infectious disease in which the human peripheral nervous system is affected after infection by specific pathogenic…”
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NPOmix: A machine learning classifier to connect mass spectrometry fragmentation data to biosynthetic gene clusters by Leão, Tiago F, Wang, Mingxun, da Silva, Ricardo, Gurevich, Alexey, Bauermeister, Anelize, Gomes, Paulo Wender P, Brejnrod, Asker, Glukhov, Evgenia, Aron, Allegra T, Louwen, Joris J R, Kim, Hyun Woo, Reher, Raphael, Fiore, Marli F, van der Hooft, Justin J J, Gerwick, Lena, Gerwick, William H, Bandeira, Nuno, Dorrestein, Pieter C

“…Microbial specialized metabolites are an important source of and inspiration for many pharmaceuticals, biotechnological products and play key roles in…”
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Campylobacter jejuni Translocation across Intestinal Epithelial Cells Is Facilitated by Ganglioside-Like Lipooligosaccharide Structures by LOUWEN, Rogier, NIEUWENHUIS, Edward E. S, BAARLEN, Peter Van, AKHMANOVA, Anna, BELKUM, Alex Van, MARREWIJK, Leonie Van, HORST-KREFT, Deborah, DE RUITER, Lilian, HEIKEMA, Astrid P, WAMEL, Willem J. B. Van, WAGENAAR, Jaap A, ENDTZ, Hubert P, SAMSOM, Janneke

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Milk Modulates Campylobacter Invasion into Caco-2 Intestinal Epithelial Cells by Louwen, Rogier, van Neerven, R J Joost

“…Raw milk is a recognized source of Campylobacter outbreaks, but pasteurization is an effective way to eliminate the causative agent of Campylobacteriosis…”
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Successful Treatment of UGT1A1 Deficiency in a Rat Model of Crigler-Najjar Disease by Intravenous Administration of a Liver-Specific Lentiviral Vector by van der Wegen, Pascal, Louwen, Rogier, Imam, Ali M, Buijs-Offerman, Ruvalic M, Sinaasappel, Maarten, Grosveld, Frank, Scholte, Bob J

“…Treatment of congenital and acquired liver disease is one of the main issues in the field of gene therapy. Self-inactivating lentiviral vectors have several…”
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O0008 SUCCESSFUL TREATMENT OF CRIGLER‐NAJJAR DISEASE BY INTRAVENOUS APPLICATION OF A LIVER‐SPECIFIC LENTIVIRAL VECTOR IN A RAT MODEL by Sinaasappel, M., Van der Wegen, P., Louwen, R., Imam, A., Grosveld, F., Scholte, B.

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O0008 SUCCESSFUL TREATMENT OF CRIGLER-NAJJAR DISEASE BY INTRAVENOUS APPLICATION OF A LIVER-SPECIFIC LENTIVIRAL VECTOR IN A RAT MODEL by Sinaasappel, M., Van der Wegen, P., Louwen, R., Imam, A., Grosveld, F., Scholte, B.

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MIBiG 3.0: a community-driven effort to annotate experimentally validated biosynthetic gene clusters by Terlouw, Barbara R, Blin, Kai, Navarro-Muñoz, Jorge C, Avalon, Nicole E, Chevrette, Marc G, Egbert, Susan, Lee, Sanghoon, Meijer, David, Recchia, Michael J J, Reitz, Zachary L, van Santen, Jeffrey A, Selem-Mojica, Nelly, Tørring, Thomas, Zaroubi, Liana, Alanjary, Mohammad, Aleti, Gajender, Aguilar, César, Al-Salihi, Suhad A A, Augustijn, Hannah E, Avelar-Rivas, J Abraham, Avitia-Domínguez, Luis A, Barona-Gómez, Francisco, Bernaldo-Agüero, Jordan, Bielinski, Vincent A, Biermann, Friederike, Booth, Thomas J, Carrion Bravo, Victor J, Castelo-Branco, Raquel, Chagas, Fernanda O, Cruz-Morales, Pablo, Du, Chao, Duncan, Katherine R, Gavriilidou, Athina, Gayrard, Damien, Gutiérrez-García, Karina, Haslinger, Kristina, Helfrich, Eric J N, van der Hooft, Justin J J, Jati, Afif P, Kalkreuter, Edward, Kalyvas, Nikolaos, Kang, Kyo Bin, Kautsar, Satria, Kim, Wonyong, Kunjapur, Aditya M, Li, Yong-Xin, Lin, Geng-Min, Loureiro, Catarina, Louwen, Joris J R, Louwen, Nico L L, Lund, George, Parra, Jonathan, Philmus, Benjamin, Pourmohsenin, Bita, Pronk, Lotte J U, Rego, Adriana, Rex, Devasahayam Arokia Balaya, Robinson, Serina, Rosas-Becerra, L Rodrigo, Roxborough, Eve T, Schorn, Michelle A, Scobie, Darren J, Singh, Kumar Saurabh, Sokolova, Nika, Tang, Xiaoyu, Udwary, Daniel, Vigneshwari, Aruna, Vind, Kristiina, Vromans, Sophie P J M, Waschulin, Valentin, Williams, Sam E, Winter, Jaclyn M, Witte, Thomas E, Xie, Huali, Yang, Dong, Yu, Jingwei, Zdouc, Mitja, Zhong, Zheng, Collemare, Jérôme, Linington, Roger G, Weber, Tilmann, Medema, Marnix H

“…With an ever-increasing amount of (meta)genomic data being deposited in sequence databases, (meta)genome mining for natural product biosynthetic pathways…”
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MS2Query: reliable and scalable MS 2 mass spectra-based analogue search by de Jonge, Niek F, Louwen, Joris J R, Chekmeneva, Elena, Camuzeaux, Stephane, Vermeir, Femke J, Jansen, Robert S, Huber, Florian, van der Hooft, Justin J J

“…Metabolomics-driven discoveries of biological samples remain hampered by the grand challenge of metabolite annotation and identification. Only few metabolites…”
Get full text