Search Results - "Loussouarn, D"
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Chitinase 3-like proteins as diagnostic and prognostic biomarkers of multiple sclerosis
Published in Multiple sclerosis (01-09-2015)“…Background: Despite sensitivity of MRI to diagnose multiple sclerosis (MS), prognostic biomarkers are still needed for optimized treatment. Objective: The…”
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2
Interactions between cancer-associated fibroblasts and tumor cells promote MCL-1 dependency in estrogen receptor-positive breast cancers
Published in Oncogene (01-04-2019)“…Selective inhibition of BCL-2 is expected to enhance therapeutic vulnerability in luminal estrogen receptor-positive breast cancers. We show here that the…”
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3
Characteristics of IDH-mutant gliomas with non-canonical IDH mutation
Published in Journal of neuro-oncology (2021)“…Background Approximately 10% of IDH -mutant gliomas harbour non-canonical IDH mutations (non- p.R132H IDH1 and IDH2 mutations). Objective The aim of this…”
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Masson's tumor revealed by an intracerebral hematoma. Case report and a review of the literature
Published in Neuro-chirurgie (01-09-2017)“…We report the case of a 56-year-old woman who underwent total resection of a Masson's tumor or intravascular papillary endothelial hyperplasia (IPEH), which…”
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Validation of UBE2C protein as a prognostic marker in node-positive breast cancer
Published in British journal of cancer (07-07-2009)“…Background: We recently identified and validated UBE2C RNA as a prognostic marker in 252 node-positive (N+) breast cancers by means of a microarray study. The…”
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Combining two biomarkers, IDH1/2 mutations and 1p/19q codeletion, to stratify anaplastic oligodendroglioma in three groups: a single-center experience
Published in Journal of neuro-oncology (01-08-2013)“…IDH1/2 mutations and 1p/19q codeletion occur frequently in anaplastic gliomas and are prognostic factors. We combined these two biomarkers to stratify patients…”
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Prognostic and therapeutic factors of gliosarcoma from a multi-institutional series
Published in Journal of neuro-oncology (01-08-2016)“…The aims of this multicentre retrospective study were to identify prognostic or therapeutic factors impacting on overall survival in patients with gliosarcoma…”
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Prognostic impact of the expression/phosphorylation of the BH3-only proteins of the BCL-2 family in glioblastoma multiforme
Published in Cell death & disease (01-11-2012)“…Apoptosis has a crucial role in anti-cancer treatment. The proteins of the BCL-2 family are core members of the apoptotic program. Thus, we postulated that…”
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Prognostic impact of syndecan-1 expression in invasive ductal breast carcinomas
Published in British journal of cancer (17-06-2008)“…Carcinoma cells lack syndecan-1 expression when they are transiting from an epithelial to a less-differentiated mesenchymal phenotype (epithelial–mesenchymal…”
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Magnetic Resonance Imaging for local preoperative staging in endometrial cancer: Nantes local experience
Published in Gynécologie, obstétrique, fertilité & sénologie (01-04-2020)“…To determine the diagnostic accuracy of magnetic resonance imaging (MRI) for local preoperative staging in endometrial cancer in our center (Centre Hospitalier…”
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Association between post-operative hPG80 (circulating progastrin) detectable level and worse prognosis in glioblastoma
Published in ESMO open (01-10-2023)“…Patients with glioblastomas have a dismal prognosis, and there is no circulating predictive or prognostic biomarker. Circulating progastrin, hPG80, is a…”
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IDH2 mutations are commonly associated with 1p/19q codeletion in diffuse adult gliomas
Published in Neuro-oncology (Charlottesville, Va.) (09-04-2018)“…716 IDH2 mutations are commonly associated with 1p/19q codeletion in diffuse adult gliomas Diffuse gliomas are classified according to the 2016 World Health…”
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PO-0661: Gliosarcoma: prognostic and therapeutics factors
Published in Radiotherapy and oncology (01-04-2016)Get full text
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14
Increase in PGE2 biosynthesis induces a Bax dependent apoptosis correlated to patients' survival in glioblastoma multiforme
Published in Oncogene (26-07-2007)“…Prostaglandin E(2) plays multiple roles both in the physiology and the physiopathology of human brain, which are not completely understood. We have identified…”
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The level of activity of the alternative lengthening of telomeres correlates with patient age in IDH-mutant ATRX-loss-of-expression anaplastic astrocytomas
Published in Acta neuropathologica communications (09-11-2019)“…All cancer cells need to maintain functional telomeres to sustain continuous cell division and proliferation. In human diffuse gliomas, functional telomeres…”
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P17.03 POST-OPERATIVE EXCLUSIVE CHEMOTHERAPY WITH PCV FOR ANAPLASTIC OLIGODENDROGLIOMA: A RETROSPECTIVE STUDY OF 35 CONFIRMED CASES
Published in Neuro-oncology (Charlottesville, Va.) (01-09-2014)“…INTRODUCTION: Anaplastic oligodendroglioma/oligoastrocytoma (AO/AOA) represent among primary brain tumors a distinct chemosensitive heterogeneous entity with…”
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6141 POSTER Frequent Molecular Alterations in Brain Metastases From Colorectal Tumours
Published in European journal of cancer (1990) (2011)Get full text
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Phosphohistone H3 labelling for histoprognostic grading of breast adenocarcinomas and computer-assisted determination of mitotic index
Published in Journal of clinical pathology (01-07-2006)“…Background: Microscopic evaluation of mitotic figures is a routine procedure in the assessment of the histoprognostic grade of tumours. Nevertheless, their…”
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An atypical case of X-linked lymphoproliferative disease revealed as a late cerebral lymphoma
Published in Journal of neuroimmunology (25-01-2010)“…Abstract X-linked lymphoproliferative disease (XLP) is an inherited immunodeficiency, partially characterized by a defect in cytotoxicity to Epstein-Barr…”
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Prognostic factors for patients treated for a recurrent FIGO stage III ovarian cancer: A retrospective study of 108 cases
Published in European journal of surgical oncology (01-11-2011)“…Abstract Aims To determine overall survival of patients treated for a first relapse of FIGO stage III ovarian cancer, outside of randomized trial, with a long…”
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