Search Results - "Lourens, C."

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  1. 1

    Quantifying anterior pelvic roll during total hip arthroplasty in the lateral decubitus position by Kurmis, Andrew P, Lourens, Ernest C

    “…Background Unintended pelvic positional change is an acknowledged intra-operative problem for hip arthroplasty, seen commonly with procedures performed in the…”
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  2. 2

    Design, synthesis and evaluation of 3-hydroxypyridin-4-ones as inhibitors of catechol-O-methyltransferase by de Beer, Johannie, Petzer, Jacobus P., Lourens, Anna C. U., Petzer, Anél

    Published in Molecular diversity (01-05-2021)
    “…The most effective treatment of Parkinson’s disease is restoring central dopamine levels with levodopa, the metabolic precursor of dopamine. However, due to…”
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  3. 3

    Serological response of foals to polyvalent and monovalent live-attenuated African horse sickness virus vaccines by Crafford, J.E, Lourens, C.W, Smit, T.K, Gardner, I.A, MacLachlan, N.J, Guthrie, A.J

    Published in Vaccine (17-06-2014)
    “…Highlights • Neutralising antibody responses to the 9 serotypes of AHSV MLV vaccine were compared. • No enhanced immunity when monovalent as opposed to…”
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  4. 4
  5. 5

    African horse sickness in naturally infected, immunised horses by WEYER, C. T., QUAN, M., JOONE, C., LOURENS, C. W., MacLACHLAN, N. J., GUTHRIE, A. J.

    Published in Equine veterinary journal (01-01-2013)
    “…Summary To determine whether subclinical cases, together with clinical cases, of African horse sickness (AHS) occur in immunised horses in field conditions,…”
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  6. 6

    Dynamics of African horse sickness virus nucleic acid and antibody in horses following immunization with a commercial polyvalent live attenuated vaccine by Weyer, C.T, Grewar, J.D, Burger, P, Joone, C, Lourens, C, MacLachlan, N.J, Guthrie, A.J

    Published in Vaccine (25-04-2017)
    “…Highlights • Administration of AHS-LAV combinations can affect RNAemia level. • Length of time between AHS-LAV combinations can affect RNAemia level. • Use of…”
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  7. 7

    Early Revision Rates of Total Hip Arthroplasty Using the Intellijoint HIP Computer Navigation System: A Study From the Australian National Joint Replacement Registry of 1911 Procedures by Lourens, Ernest C., Kurmis, Andrew P., Holder, Carl, de Steiger, Richard N.

    Published in Arthroplasty today (01-12-2022)
    “…Total hip arthroplasty (THA) is an effective treatment for symptomatic hip osteoarthritis. The aim of this study was to determine the revision outcome of…”
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  8. 8

    Development and optimisation of a duplex real-time reverse transcription quantitative PCR assay targeting the VP7 and NS2 genes of African horse sickness virus by Quan, M., Lourens, C.W., MacLachlan, N.J., Gardner, I.A., Guthrie, A.J.

    Published in Journal of virological methods (01-07-2010)
    “…Nucleotide sequences of 52 South African isolates of African horse sickness virus (AHSV) collected during 2004–2005 and including viruses of all nine AHSV…”
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  9. 9

    Passive transfer and rate of decay of maternal antibody against African horse sickness virus in South African Thoroughbred foals by Crafford, J. E., Lourens, C. W., Gardner, I. A., Maclachlan, N. J., Guthrie, A. J.

    Published in Equine veterinary journal (01-09-2013)
    “…Summary Reasons for performing study African horse sickness is an insect‐transmitted, noncontagious disease of equids caused by African horse sickness virus…”
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  10. 10

    Electromechanical abdominal massage and colonic function in individuals with a spinal cord injury and chronic bowel problems by Janssen, T W J, Prakken, E S, Hendriks, J M S, Lourens, C, van der Vlist, J, Smit, C A J

    Published in Spinal cord (01-09-2014)
    “…Study Design: A prospective intervention of noninvasive abdominal massage using an electromechanical apparatus on bowel function in individuals with spinal…”
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  11. 11

    Sulfanylphthalonitrile analogues as selective and potent inhibitors of monoamine oxidase B by Van der Walt, Mietha M., Terre’Blanche, Gisella, Lourens, Anna C.U., Petzer, Anél, Petzer, Jacobus P.

    Published in Bioorganic & medicinal chemistry letters (15-12-2012)
    “…It has recently been reported that nitrile containing compounds frequently act as potent monoamine oxidase B (MAO-B) inhibitors. Modelling studies suggest that…”
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  12. 12

    Design, synthesis and biological evaluation of 6-aryl-1,6-dihydro-1,3,5-triazine-2,4-diamines as antiplasmodial antifolates by Lourens, Anna C U, Gravestock, David, van Zyl, Robyn L, Hoppe, Heinrich C, Kolesnikova, Natasha, Taweechai, Supannee, Yuthavong, Yongyuth, Kamchonwongpaisan, Sumalee, Rousseau, Amanda L

    Published in Organic & biomolecular chemistry (01-01-2016)
    “…The design, synthesis and biological evaluation of a series of 6-aryl-1,6-dihydro-1,3,5-triazine-2,4-diamines is described. These compounds exhibited in vitro…”
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  13. 13

    Carbamate substituted 2-amino-4,6-diphenylpyrimidines as adenosine receptor antagonists by Robinson, Sarel J., Petzer, Jacobus P., Rousseau, Amanda L., Terre’Blanche, Gisella, Petzer, Anél, Lourens, Anna C.U.

    Published in Bioorganic & medicinal chemistry letters (01-02-2016)
    “…[Display omitted] A novel series of carbamate substituted 2-amino-4,6-diphenylpyrimidines was evaluated as potential dual adenosine A1 and A2A receptor…”
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  14. 14

    Development of a real time polymerase chain reaction assay for equine encephalosis virus by Rathogwa, N.M., Quan, M., Smit, J.Q., Lourens, C., Guthrie, A.J., van Vuuren, M.

    Published in Journal of virological methods (01-01-2014)
    “…•The S7 genes of 38 EEV isolates were sequenced.•A real-time RT-PCR assay for equine encephalosis virus was developed.•The 95% limit of detection of the EEV…”
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  15. 15

    Monoamine oxidase inhibitory activities of heterocyclic chalcones by Minders, Corné, Petzer, Jacobus P., Petzer, Anél, Lourens, Anna C.U.

    Published in Bioorganic & medicinal chemistry letters (15-11-2015)
    “…[Display omitted] Studies have shown that natural and synthetic chalcones (1,3-diphenyl-2-propen-1-ones) possess monoamine oxidase (MAO) inhibition activities…”
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  16. 16

    Synthesis and evaluation of chromone derivatives as inhibitors of monoamine oxidase by Mpitimpiti, Annah N., Petzer, Jacobus P., Petzer, Anél, Jordaan, Johannes H. L., Lourens, Anna C. U.

    Published in Molecular diversity (01-11-2019)
    “…Based on reports that chromone compounds are good potency inhibitors of monoamine oxidase (MAO), the present study evaluates the effect of substitution with…”
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  17. 17

    Selected furanochalcones as inhibitors of monoamine oxidase by Robinson, Sarel J., Petzer, Jacobus P., Petzer, Anél, Bergh, Jacobus J., Lourens, Anna C.U.

    Published in Bioorganic & medicinal chemistry letters (01-09-2013)
    “…The validity of the chalcone scaffold for the design of inhibitors of monoamine oxidase has previously been illustrated. In a systematic attempt to investigate…”
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  18. 18

    South African Helichrysum species: A review of the traditional uses, biological activity and phytochemistry by Lourens, A.C.U., Viljoen, A.M., van Heerden, F.R.

    Published in Journal of ethnopharmacology (28-10-2008)
    “…In South Africa, the genus Helichrysum is widely used in traditional medicine. The uses are well documented although renaming of species and the resulting…”
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  19. 19

    The adenosine A(2A) antagonistic properties of selected C8-substituted xanthines by Van der Walt, Mietha M, Terre'Blanche, Gisella, Petzer, Anél, Lourens, Anna C U, Petzer, Jacobus P

    Published in Bioorganic chemistry (01-08-2013)
    “…The adenosine A2A receptor is considered to be an important target for the development of new therapies for Parkinson's disease. Several antagonists of the A2A…”
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  20. 20

    In vitro biological activity and essential oil composition of four indigenous South African Helichrysum species by Lourens, A.C.U., Reddy, D., Başer, K.H.C., Viljoen, A.M., Van Vuuren, S.F.

    Published in Journal of ethnopharmacology (01-12-2004)
    “…Helichrysum species are used widely to treat various medical conditions. In this study, the anti-microbial, anti-oxidant (DPPH assay) and anti-inflammatory…”
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