Search Results - "Lourens, C"
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1
Quantifying anterior pelvic roll during total hip arthroplasty in the lateral decubitus position
Published in Journal of orthopaedic surgery and research (14-11-2023)“…Background Unintended pelvic positional change is an acknowledged intra-operative problem for hip arthroplasty, seen commonly with procedures performed in the…”
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2
Design, synthesis and evaluation of 3-hydroxypyridin-4-ones as inhibitors of catechol-O-methyltransferase
Published in Molecular diversity (01-05-2021)“…The most effective treatment of Parkinson’s disease is restoring central dopamine levels with levodopa, the metabolic precursor of dopamine. However, due to…”
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3
Serological response of foals to polyvalent and monovalent live-attenuated African horse sickness virus vaccines
Published in Vaccine (17-06-2014)“…Highlights • Neutralising antibody responses to the 9 serotypes of AHSV MLV vaccine were compared. • No enhanced immunity when monovalent as opposed to…”
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Corrigendum to "Early Revision Rates of Total Hip Arthroplasty Using the Intellijoint HIP Computer Navigation System: A Study From the Australian National Joint Replacement Registry of 1911 Procedures." [Arthroplasty Today 18 (2022) 149-156]
Published in Arthroplasty today (01-12-2023)“…[This corrects the article DOI: 10.1016/j.artd.2022.09.019.]…”
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5
African horse sickness in naturally infected, immunised horses
Published in Equine veterinary journal (01-01-2013)“…Summary To determine whether subclinical cases, together with clinical cases, of African horse sickness (AHS) occur in immunised horses in field conditions,…”
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Dynamics of African horse sickness virus nucleic acid and antibody in horses following immunization with a commercial polyvalent live attenuated vaccine
Published in Vaccine (25-04-2017)“…Highlights • Administration of AHS-LAV combinations can affect RNAemia level. • Length of time between AHS-LAV combinations can affect RNAemia level. • Use of…”
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Early Revision Rates of Total Hip Arthroplasty Using the Intellijoint HIP Computer Navigation System: A Study From the Australian National Joint Replacement Registry of 1911 Procedures
Published in Arthroplasty today (01-12-2022)“…Total hip arthroplasty (THA) is an effective treatment for symptomatic hip osteoarthritis. The aim of this study was to determine the revision outcome of…”
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8
Development and optimisation of a duplex real-time reverse transcription quantitative PCR assay targeting the VP7 and NS2 genes of African horse sickness virus
Published in Journal of virological methods (01-07-2010)“…Nucleotide sequences of 52 South African isolates of African horse sickness virus (AHSV) collected during 2004–2005 and including viruses of all nine AHSV…”
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Passive transfer and rate of decay of maternal antibody against African horse sickness virus in South African Thoroughbred foals
Published in Equine veterinary journal (01-09-2013)“…Summary Reasons for performing study African horse sickness is an insect‐transmitted, noncontagious disease of equids caused by African horse sickness virus…”
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10
Electromechanical abdominal massage and colonic function in individuals with a spinal cord injury and chronic bowel problems
Published in Spinal cord (01-09-2014)“…Study Design: A prospective intervention of noninvasive abdominal massage using an electromechanical apparatus on bowel function in individuals with spinal…”
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11
Sulfanylphthalonitrile analogues as selective and potent inhibitors of monoamine oxidase B
Published in Bioorganic & medicinal chemistry letters (15-12-2012)“…It has recently been reported that nitrile containing compounds frequently act as potent monoamine oxidase B (MAO-B) inhibitors. Modelling studies suggest that…”
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Design, synthesis and biological evaluation of 6-aryl-1,6-dihydro-1,3,5-triazine-2,4-diamines as antiplasmodial antifolates
Published in Organic & biomolecular chemistry (01-01-2016)“…The design, synthesis and biological evaluation of a series of 6-aryl-1,6-dihydro-1,3,5-triazine-2,4-diamines is described. These compounds exhibited in vitro…”
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13
Carbamate substituted 2-amino-4,6-diphenylpyrimidines as adenosine receptor antagonists
Published in Bioorganic & medicinal chemistry letters (01-02-2016)“…[Display omitted] A novel series of carbamate substituted 2-amino-4,6-diphenylpyrimidines was evaluated as potential dual adenosine A1 and A2A receptor…”
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14
Development of a real time polymerase chain reaction assay for equine encephalosis virus
Published in Journal of virological methods (01-01-2014)“…•The S7 genes of 38 EEV isolates were sequenced.•A real-time RT-PCR assay for equine encephalosis virus was developed.•The 95% limit of detection of the EEV…”
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15
Monoamine oxidase inhibitory activities of heterocyclic chalcones
Published in Bioorganic & medicinal chemistry letters (15-11-2015)“…[Display omitted] Studies have shown that natural and synthetic chalcones (1,3-diphenyl-2-propen-1-ones) possess monoamine oxidase (MAO) inhibition activities…”
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Synthesis and evaluation of chromone derivatives as inhibitors of monoamine oxidase
Published in Molecular diversity (01-11-2019)“…Based on reports that chromone compounds are good potency inhibitors of monoamine oxidase (MAO), the present study evaluates the effect of substitution with…”
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Selected furanochalcones as inhibitors of monoamine oxidase
Published in Bioorganic & medicinal chemistry letters (01-09-2013)“…The validity of the chalcone scaffold for the design of inhibitors of monoamine oxidase has previously been illustrated. In a systematic attempt to investigate…”
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South African Helichrysum species: A review of the traditional uses, biological activity and phytochemistry
Published in Journal of ethnopharmacology (28-10-2008)“…In South Africa, the genus Helichrysum is widely used in traditional medicine. The uses are well documented although renaming of species and the resulting…”
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The adenosine A(2A) antagonistic properties of selected C8-substituted xanthines
Published in Bioorganic chemistry (01-08-2013)“…The adenosine A2A receptor is considered to be an important target for the development of new therapies for Parkinson's disease. Several antagonists of the A2A…”
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In vitro biological activity and essential oil composition of four indigenous South African Helichrysum species
Published in Journal of ethnopharmacology (01-12-2004)“…Helichrysum species are used widely to treat various medical conditions. In this study, the anti-microbial, anti-oxidant (DPPH assay) and anti-inflammatory…”
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