Search Results - "Lourenco, Filipa"
-
1
Looking at the blood–brain barrier: Molecular anatomy and possible investigation approaches
Published in Brain Research Reviews (24-09-2010)“…Abstract The blood–brain barrier (BBB) is a dynamic and complex interface between blood and the central nervous system that strictly controls the exchanges…”
Get full text
Journal Article -
2
Antiphospholipid syndrome: state of the art on clinical practice guidelines
Published in Rheumatic & musculoskeletal diseases open (01-10-2018)“…Antiphospholipid syndrome (APS) is a rare disease characterised by venous and/or arterial thrombosis, pregnancy complications and the presence of specific…”
Get full text
Journal Article -
3
Fatal CTLA‐4 heterozygosity with autoimmunity and recurrent infections: a de novo mutation
Published in Clinical case reports (01-12-2017)“…Key Clinical Message Primary immunodeficiency disorders are rarely diagnosed in adults but must be considered in the differential diagnosis of combined…”
Get full text
Journal Article -
4
3D Niche‐Inspired Scaffolds as a Stem Cell Delivery System for the Regeneration of the Osteochondral Interface
Published in Advanced materials (Weinheim) (01-08-2024)“…The regeneration of the osteochondral unit represents a challenge due to the distinct cartilage and bone phases. Current strategies focus on the development of…”
Get full text
Journal Article -
5
Impact of Neuroinflammation on Hippocampal Neurogenesis: Relevance to Aging and Alzheimer's Disease
Published in Journal of Alzheimer's disease (01-01-2017)“…The cognitive reserve is associated with the capacity of the brain to maintain cognitive performance in spite of being challenged by stressful degenerative…”
Get more information
Journal Article -
6
MIR-NATs repress MAPT translation and aid proteostasis in neurodegeneration
Published in Nature (London) (03-06-2021)“…The human genome expresses thousands of natural antisense transcripts (NAT) that can regulate epigenetic state, transcription, RNA stability or translation of…”
Get full text
Journal Article -
7
Evaluating the genotoxicity of cellulose nanofibrils in a co-culture of human lung epithelial cells and monocyte-derived macrophages
Published in Toxicology letters (01-07-2018)“…•Cellulose nanofibrils (CNF) produced from Eucalyptus globulus were characterized.•A co-culture of lung alveolar cells and macrophages was used to analyse CNF…”
Get full text
Journal Article -
8
Multiple arthritis: three in one
Published in BMJ case reports (08-03-2012)Get full text
Journal Article -
9
Antiphospholipid syndrome and recurrent thrombosis – limitations of current treatment strategies
Published in BMJ case reports (08-03-2012)“…Antiphospholipid syndrome (APS) is a systemic autoimmune disorder that is characterised by the presence of antiphospholipid antibodies and a common cause of…”
Get full text
Journal Article -
10
Long COVID Symptoms in Non-Hospitalised Patients: A Retrospective Study
Published in Acta médica portuguesa (01-10-2023)“…Introduction: The COVID-19 pandemic has presented numerous challenges to healthcare systems. As the number of affected individuals continues to rise, it is…”
Get full text
Journal Article -
11
Installation of click-type functional groups enable the creation of an additive manufactured construct for the osteochondral interface
Published in Biofabrication (01-01-2023)“…Melt extrusion-based additive manufacturing (AM) is often used to fabricate scaffolds for osteochondral (OC) regeneration. However, there are two shortcomings…”
Get more information
Journal Article -
12
Blood–Brain Barrier and Bilirubin: Clinical Aspects and Experimental Data
Published in Archives of medical research (01-11-2014)“…The blood–brain barrier (BBB) is a complex and dynamic structure that plays a key role in central nervous system (CNS) homeostasis. It strictly regulates the…”
Get full text
Journal Article -
13
Analysis of the In Vitro Toxicity of Nanocelluloses in Human Lung Cells as Compared to Multi-Walled Carbon Nanotubes
Published in Nanomaterials (Basel, Switzerland) (22-04-2022)“…Cellulose micro/nanomaterials (CMNM), comprising cellulose microfibrils (CMF), nanofibrils (CNF), and nanocrystals (CNC), are being recognized as promising…”
Get full text
Journal Article -
14
Progressive Multifocal Leukoencephalopathy and Systemic Lupus Erythematosus: Focus on Etiology
Published in Case reports in neurology (01-01-2016)“…Progressive multifocal leukoencephalopathy (PML) caused by reactivation of the JC virus (JCV), a human polyomavirus, occurs in autoimmune disorders, most…”
Get full text
Journal Article -
15
Assessing the Genotoxicity of Cellulose Nanomaterials in a Co-Culture of Human Lung Epithelial Cells and Monocyte-Derived Macrophages
Published in Bioengineering (Basel) (01-08-2023)“…Cellulose micro/nanomaterials (CMNMs) are innovative materials with a wide spectrum of industrial and biomedical applications. Although cellulose has been…”
Get full text
Journal Article -
16
Psychogenic purpura – remembering a rare image
Published in Medicina Clínica Práctica (01-01-2022)Get full text
Journal Article -
17
Tricellulin expression in brain endothelial and neural cells
Published in Cell and tissue research (01-03-2013)“…Tricellulin is a tight junction (TJ) protein, which is not only concentrated at tricellular contacts but also present at bicellular contacts between epithelial…”
Get full text
Journal Article -
18
Time-dependent dual effects of high levels of unconjugated bilirubin on the human blood-brain barrier lining
Published in Frontiers in cellular neuroscience (10-05-2012)“…In neonatal jaundice, high levels of unconjugated bilirubin (UCB) may induce neurological dysfunction (BIND). Recently, it was observed that UCB induces…”
Get full text
Journal Article -
19
On the toxicity of cellulose nanocrystals and nanofibrils in animal and cellular models
Published in Cellulose (London) (01-07-2020)“…The need for reaching environmental sustainability encourages research on new cellulose-based materials for a broad range of applications across many sectors…”
Get full text
Journal Article -
20
A Humanized In Vitro Model of Innervated Skin for Transdermal Analgesic Testing
Published in Macromolecular bioscience (01-01-2023)“…Sensory innervation of the skin is essential for its function, homeostasis, and wound healing mechanisms. Thus, to adequately model the cellular…”
Get full text
Journal Article