Search Results - "Loukas, Vassilios"
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Amino Acid Based Synthesis of Chiral Long Chain Diamines and Tetramines
Published in Molecules (Basel, Switzerland) (01-10-2002)“…A method for the synthesis of long chain diamines and tetramines starting from natural α-amino acids is reported. Diamines and tetramines were prepared through…”
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Inhibition of Group IVA Cytosolic Phospholipase A2 by Novel 2-Oxoamides in Vitro, in Cells, and in Vivo
Published in Journal of medicinal chemistry (01-07-2004)“…The Group IVA cytosolic phospholipase A2 (GIVA PLA2) is a particularly attractive target for drug development because it is the rate-limiting provider of…”
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Efficient protocols for the synthesis of enantiopure γ-amino acids with proteinogenic side chains
Published in Journal of peptide science (01-05-2003)“…The synthesis of enantiopure γ‐substituted γ‐amino acids with proteinogenic side chains, starting from the corresponding natural α‐amino acids, was studied…”
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Structure−Activity Relationship of 2-Oxoamide Inhibition of Group IVA Cytosolic Phospholipase A2 and Group V Secreted Phospholipase A2
Published in Journal of medicinal chemistry (23-08-2007)“…The Group IVA cytosolic phospholipase A2 (GIVA cPLA2) is a key provider of substrates for the production of eicosanoids and platelet-activating factor. We…”
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Inhibition of Group IVA Cytosolic Phospholipase A 2 by Novel 2-Oxoamides in Vitro, in Cells, and in Vivo
Published in Journal of medicinal chemistry (01-07-2004)Get full text
Journal Article