Search Results - "Louis, Nundia"

Resetting the epigenetic balance of Polycomb and COMPASS function at enhancers for cancer therapy by Wang, Lu, Zhao, Zibo, Ozark, Patrick A., Fantini, Damiano, Marshall, Stacy A., Rendleman, Emily J., Cozzolino, Kira A., Louis, Nundia, He, Xingyao, Morgan, Marc A., Takahashi, Yoh-hei, Collings, Clayton K., Smith, Edwin R., Ntziachristos, Panagiotis, Savas, Jeffrey N., Zou, Lihua, Hashizume, Rintaro, Meeks, Joshua J., Shilatifard, Ali

“…The lysine methyltransferase KMT2C (also known as MLL3), a subunit of the COMPASS complex, implements monomethylation of Lys4 on histone H3 (H3K4) at gene…”
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Simultaneous and sequential hemorrhage of multiple cerebral cavernous malformations: a case report by Louis, Nundia, Marsh, Robert

“…The etiology of cerebral cavernous malformation hemorrhage is not well understood. Causative physiologic parameters preceding hemorrhagic cavernous…”
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Proposal for the Rapid Reversal of Coagulopathy in Patients with Nonoperative Head Injuries on Anticoagulants and/or Antiplatelet Agents: A Case Study and Literature Review by Watson, Victoria L, Louis, Nundia, Seminara, Brittany V, Muizelaar, J Paul, Alberico, Anthony

“…Abstract BACKGROUND Emergency room physicians, trauma teams, and neurosurgeons are seeing increasing numbers of head-injured patients on anticoagulants, many…”
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New therapeutic approaches for brainstem tumors: a comparison of delivery routes using nanoliposomal irinotecan in an animal model by Louis, Nundia, Liu, Sharon, He, Xingyao, Drummond, Daryl C., Noble, Charles O., Goldman, Stewart, Mueller, Sabine, Bankiewicz, Krystof, Gupta, Nalin, Hashizume, Rintaro

“…Despite the advances in imaging, surgery and radiotherapy, the majority of patients with brainstem gliomas die within 2 years after initial diagnosis. Factors…”
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Inhibition of polo-like kinase 4 (PLK4): a new therapeutic option for rhabdoid tumors and pediatric medulloblastoma by Sredni, Simone Treiger, Bailey, Anders W, Suri, Amreena, Hashizume, Rintaro, He, Xingyao, Louis, Nundia, Gokirmak, Tufan, Piper, David R, Watterson, Daniel M, Tomita, Tadanori

“…Rhabdoid tumors (RT) are highly aggressive and vastly unresponsive embryonal tumors. They are the most common malignant CNS tumors in infants below 6 months of…”
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Radiosensitization by Histone H3 Demethylase Inhibition in Diffuse Intrinsic Pontine Glioma by Katagi, Hiroaki, Louis, Nundia, Unruh, Dusten, Sasaki, Takahiro, He, Xingyao, Zhang, Ali, Ma, Quanhong, Piunti, Andrea, Shimazu, Yosuke, Lamano, Jonathan B, Carcaboso, Angel M, Tian, Xiao, Seluanov, Andrei, Gorbunova, Vera, Laurie, Kathryn L, Kondo, Akihide, Wadhwani, Nitin R, Lulla, Rishi, Goldman, Stewart, Venneti, Sriram, Becher, Oren J, Zou, Lihua, Shilatifard, Ali, Hashizume, Rintaro

“…Radiotherapy (RT) has long been and remains the only treatment option for diffuse intrinsic pontine glioma (DIPG). However, all patients show evidence of…”
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PDTM-36. NEW THERAPEUTIC APPROACH FOR BRAINSTEM GLIOMA: INTRANASAL DELIVERY OF NANOLIPOSOMAL SN-38 by He, Xingyao, Zhang, Peng, Louis, Nundia, Katagi, Hiroaki, Balyasnikova, Irina, Horbinski, Craig, Goldman, Stewart, Hashizume, Rintaro

“…Abstract INTRODUCTION Children with diffuse intrinsic pontine gliomas (DIPGs) die within 2 years after initial diagnosis. The infiltrative nature and anatomic…”
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DIPG-33. NEW THERAPEUTIC APPROACH FOR BRAINSTEM GLIOMA: INTRANASAL DELIVERY OF NANOLIPOSOMAL SN-38 by He, Xingyao, Louis, Nundia, Katagi, Hiroaki, Zhang, Peng, Balyasnikova, Irina, Horbinski, Craig, Goldman, Stewart, Hashizume, Rintaro

“…Abstract INTRODUCTION Children with diffuse intrinsic pontine gliomas (DIPGs) die within 2 years after initial diagnosis. The infiltrative nature and anatomic…”
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SCDT-20. NEW THERAPEUTIC APPROACH FOR BRAINSTEM GLIOMA: INTRANASAL DELIVERY OF NANOLIPOSOMAL SN-38 by He, Xingyao, Louis, Nundia, Zhang, Peng, Balyasnikova, Irina, Horbinski, Craig, Goldman, Stewart, Hashizume, Rintaro

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PDTM-37. NEW THERAPEUTIC APPROACH FOR BRAINSTEM GLIOMA: INTRANASAL DELIVERY OF NANOLIPOSOMAL SN-38 by He, Xingyao, Louis, Nundia, Zhang, Peng, Balyasnikova, Irina, Horbinski, Craig, Goldman, Stewart, Hashizume, Rintaro

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DIPG-36. NOVEL THERAPEUTIC APPROACHES USING NANOLIPOSMAL SN-38 FOR THE TREATMENT OF HUMAN BRAINSTEM GLIOMA by He, Xingyao, Louis, Nundia, Hashizume, Rintaro, Zhang, Peng, Balyasnikova, Irina, Horbinski, Craig, Goldman, Stewart

“…INTRODUCTION: Children with diffuse intrinsic pontine gliomas (DIPGs) die within 2 years after initial diagnosis. The infiltrative nature and anatomic location…”
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DIPG-24. TARGETED INHIBITION OF JMJD3 AND BET BROMODOMAIN PROTEINS FOR THE TREATMENT OF DIFFUSE INTRINSIC PONTINE GLIOMAS by Katagi, Hiroaki, Louis, Nundia, He, Xingyao, Loughlin, Kathryn, Zhang, Ali, Ozark, Patrick, Horbinski, Craig, Lulla, Rishi, Saratsis, Amanda, Goldman, Stewart, David James, C, Shilatifard, Ali, Hashizume, Rintaro

“…Abstract Recent discovery of somatic histone gene mutations, resulting in replacement of lysine 27 by methionine (K27M) in the encoded histone H3.3 proteins,…”
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PDTM-44. RADIATION DNA DAMAGE REPAIR INHIBITION BY GSK-J4 INDUCED CHROMATIN COMPACTION IN DIPG by Louis, Nundia, He, Xingyao, Piunti, Andrea, Morgan, Marc, Unruh, Dusten, Saratsis, Amanda, Lulla, Rishi, Fangusaro, Jason R, Horbinski, Craig, Goldman, Stewart, James, C David, Shilatifard, Ali, Hashizume, Rintaro

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PDTM-05. RADIATION DNA DAMAGE REPAIR INHIBITION BY GSK-J4 INDUCED CHROMATIN COMPACTION IN DIPG by Louis, Nundia, Zou, Lihua, Unruh, Dusten, A. Ozark, Patrick, Piunti, Andrea, Gorbunova, Vera, He, Xingyao, Katagi, Hiroaki, Gryzlo, Daniel, Zhang, Ali, M. Saratsis, Amanda, Laurie, Kathryn, Lulla, Rishi, Fangusaro, Jason, Horbinski, Craig, Goldman, Stewart, James, C David, Shilatifard, Ali, Hashizume, Rintaro

“…Abstract INTRODUCTION Focal radiation therapy has long been and remains the only treatment option for diffuse intrinsic pontine glioma (DIPG). However, all…”
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DIPG-28. RADIATION DNA DAMAGE REPAIR INHIBITION BY GSK-J4 INDUCED CHROMATIN COMPACTION IN DIPG by Louis, Nundia, He, Xingyao, Plunti, Andrea, Saratsis, Amanda, Lulla, Rishi, Fangusaro, Jason, Horbinski, Craig, Goldman, Stewart, James, David, Shilatifard, Ali, Hashizume, Rintaro

“…INTRODUCTION: Focal radiation therapy has long been and still remains the only treatment option for diffuse intrinsic pontine glioma (DIPG). However, all…”
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DIPG-63. RADIATION DNA DAMAGE REPAIR INHIBITION BY GSK-J4 INDUCED CHROMATIN COMPACTION IN DIPG by Louis, Nundia, He, Xingyao, Unruh, Dustin, Piunti, Andrea, Zou, Lihua, Ozark, Patrick, Tianc, Xiao, Gorbunova, Vera, Katagi, Hiroaki, Gryzlo, Daniel, Zhang, Ali, Saratsis, Amanda, Laurie, Kathryn, Lulla, Rishi, Fangusaro, Jason, Horbinski, Craig, Goldman, Stewart, David James, C, Shilatifard, Ali, Hashizume, Rintaro

“…Abstract INTRODUCTION Focal radiation therapy remains the only treatment option for diffuse intrinsic pontine glioma (DIPG). However, all patients show…”
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PDTM-28. TARGETED INHIBITION OF EZH2 AND BET BROMODOMAIN PROTEINS FOR THE TREATMENT OF DIFFUSE INTRINSIC PONTINE GLIOMAS by Piunti, Andrea, Morgan, Marc, Bartom, Elizabeth, Louis, Nundia, He, Xingyao, Zhang, Ali, Horbinski, Craig, Marshall, Stacy, Rendleman, Emily, Takahashi, Yoh-hei, Misharin, Alexander, Abshiru, Nebiyu, Lulla, Rishi, Saratsis, Amanda, Kelleher, Neil, James, C David, Shilatifard, Ali, Hashizume, Rintaro

“…Recent discovery of somatic histone gene mutations, resulting in replacement of lysine 27 by methionine (K27M) in the encoded histone H3.3 proteins, in diffuse…”
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Marked Elevation of Carcinoembryonic Antigen Without an Identified Primary Gastrointestinal Tumor by Salabei, Joshua K, Upadhyay, Dhaval, Haider, Asad, Nanajian, Anthony, Frimer, Leora, Charles, Kipson, Ismail, Zeeshan H, Imboywa, Selina, Khan, Awaad, Louis, Nundia, Iyer, Uma G

“…Whether profound carcinoembryonic antigen (CEA) elevations, such as > 20 times the upper limit of normal, are of diagnostic use remain unknown. Herein, we…”
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Marked Elevation of Carcinoembryonic Antigen Without an Identified Primary Gastrointestinal Tumor by Salabei, Joshua K, Upadhyay, Dhaval, Haider, Asad, Nanajian, Anthony, Frimer, Leora, Charles, Kipson, Ismail, Zeeshan H, Imboywa, Selina, Khan, Awaad, Louis, Nundia, Iyer, Uma G

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