Search Results - "Louis, Fiona"
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Engineered whole cut meat-like tissue by the assembly of cell fibers using tendon-gel integrated bioprinting
Published in Nature communications (24-08-2021)“…With the current interest in cultured meat, mammalian cell-based meat has mostly been unstructured. There is thus still a high demand for artificial steak-like…”
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3D collagen microfibers stimulate the functionality of preadipocytes and maintain the phenotype of mature adipocytes for long term cultures
Published in Acta biomaterialia (15-01-2019)“…[Display omitted] Although adipose tissue is one of the most abundant tissues of the human body, its reconstruction remains a competitive challenge. The…”
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Mimicking Wagyu beef fat in cultured meat: Progress in edible bovine adipose tissue production with controllable fatty acid composition
Published in Materials today bio (01-08-2023)“…Since the current process of livestock meat production has considerable effects on the global environment, leading to high emissions of greenhouse gases,…”
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Injectable Prevascularized Mature Adipose Tissues (iPAT) to Achieve Long‐Term Survival in Soft Tissue Regeneration
Published in Advanced healthcare materials (01-12-2022)“…Soft tissue regeneration remains a challenge in reconstructive surgery. So far, both autologous fat implantations and artificial implants methods used in…”
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In vitro fabrication and application of engineered vascular hydrogels
Published in Polymer journal (01-08-2020)“…Vascularization is one of the most challenging areas of tissue engineering research. Vascular engineering holds the key to counteracting cardiovascular…”
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High-throughput drug screening models of mature adipose tissues which replicate the physiology of patients’ Body Mass Index (BMI)
Published in Bioactive materials (01-01-2022)“…Obesity is a complex and incompletely understood disease, but current drug screening strategies mostly rely on immature in vitro adipose models which cannot…”
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RhoGTPases as Key Players in Mammalian Cell Adaptation to Microgravity
Published in BioMed research international (01-01-2015)“…A growing number of studies are revealing that cells reorganize their cytoskeleton when exposed to conditions of microgravity. Most, if not all, of the…”
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Cationic polymer effect on brown adipogenic induction of dedifferentiated fat cells
Published in Materials today bio (01-08-2024)“…Obesity and its associated comorbidities place a substantial burden on public health. Given the considerable potential of brown adipose tissue in addressing…”
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Comparative analysis of the residues of granular support bath materials on printed structures in embedded extrusion printing
Published in Biofabrication (03-05-2023)“…Embedded extrusion printing facilitates the fabrication of complex biological structures using soft hydrogels that are challenging to construct using…”
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Bioprinted Vascularized Mature Adipose Tissue with Collagen Microfibers for Soft Tissue Regeneration
Published in Cyborg and bionic systems (01-01-2021)“…The development of soft tissue regeneration has recently gained importance due to safety concerns about artificial breast implants. Current autologous fat…”
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Control of blood capillary networks and holes in blood-brain barrier models by regulating elastic modulus of scaffolds
Published in Materials today bio (01-08-2023)“…The blood-brain barrier (BBB) is a type of capillary network characterized by a highly selective barrier, which restricts the transport of substances between…”
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Characterization of macrophages associated with human skin models exposed to UV radiation
Published in Communications biology (08-10-2024)“…Skin macrophages play important roles in the response to external stimuli. Human skin equivalents (HSEs) incorporating the human monocytic cell line THP-1 were…”
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Brain microvascular endothelial cells derived from human induced pluripotent stem cells as in vitro model for assessing blood-brain barrier transferrin receptor-mediated transcytosis
Published in Materials today bio (01-03-2022)“…The blood-brain barrier (BBB), a selective barrier formed by brain microvascular endothelial cells (BMEC), represents a major challenge for the efficient…”
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14
Fabrication of Blood Capillary Models for Live Imaging Microarray Analysis
Published in Micromachines (Basel) (27-07-2020)“…Conventional microarray analysis usually deals with the monolayer or two-dimensional (2D) assays for the high-throughput screening applications. Even though…”
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Direct Conversion of Human Fibroblasts into Adipocytes Using a Novel Small Molecular Compound: Implications for Regenerative Therapy for Adipose Tissue Defects
Published in Cells (Basel, Switzerland) (09-03-2021)“…There is a need in plastic surgery to prepare autologous adipocytes that can be transplanted in patients to reconstruct soft tissue defects caused by tumor…”
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A Near‐Infrared Organic Fluorescent Probe for Broad Applications for Blood Vessels Imaging by High‐Throughput Screening via 3D‐Blood Vessel Models
Published in Small methods (01-08-2021)“…Blood vessels are present in all of the organs, reflecting their importance for oxygen and nutrient delivery to the cells. Until now, no organic fluorophore…”
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Mechanism assay of interaction between blood vessels-near infrared probe and cell surface marker proteins of endothelial cells
Published in Materials today bio (01-06-2022)“…In vivo blood vessels imaging is crucial to study blood vessels related diseases in real-time. For this purpose, fluorescent based imaging is one of the utmost…”
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RhoGTPase stimulation is associated with strontium chloride treatment to counter simulated microgravity-induced changes in multipotent cell commitment
Published in NPJ microgravity (25-01-2017)“…Microgravity-related cytoskeletal disorganization is associated with an altered balance between osteoblastogenesis and adipogenesis of multipotent cells…”
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Polyelectrolyte nanofilms on cell surface can induce brown adipogenic differentiation of DFATs
Published in Biochemical and biophysical research communications (12-11-2024)“…Obesity and its related health issues significantly burden public health systems. Brown adipose tissue holds promise for addressing metabolic disorders and…”
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Improving stability of human three dimensional skin equivalents using plasma surface treatment
Published in Biotechnology and bioengineering (01-06-2024)“…In developing three-dimensional (3D) human skin equivalents (HSEs), preventing dermis and epidermis layer distortion due to the contraction of hydrogels by…”
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