Search Results - "Louie, Tracey"

A novel orally active small molecule potently induces G1 arrest in primary myeloma cells and prevents tumor growth by specific inhibition of cyclin-dependent kinase 4/6 by BAUGHN, Linda B, DI LIBERTO, Maurizio, CHEN-KIANG, Selina, KAIDA WU, TOOGOOD, Peter L, LOUIE, Tracey, GOTTSCHALK, Rachel, NIESVIZKY, Ruben, CHO, Hearn, ELY, Scott, MOORE, Malcolm A. S

“…Cell cycle deregulation is central to the initiation and fatality of multiple myeloma, the second most common hematopoietic cancer, although impaired apoptosis…”
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Prolonged early G(1) arrest by selective CDK4/CDK6 inhibition sensitizes myeloma cells to cytotoxic killing through cell cycle-coupled loss of IRF4 by Huang, Xiangao, Di Liberto, Maurizio, Jayabalan, David, Liang, Jun, Ely, Scott, Bretz, Jamieson, Shaffer, 3rd, Arthur L, Louie, Tracey, Chen, Isan, Randolph, Sophia, Hahn, William C, Staudt, Louis M, Niesvizky, Ruben, Moore, Malcolm A S, Chen-Kiang, Selina

“…Dysregulation of cyclin-dependent kinase 4 (CDK4) and CDK6 by gain of function or loss of inhibition is common in human cancer, including multiple myeloma, but…”
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Prolonged early G1 arrest by selective CDK4/CDK6 inhibition sensitizes myeloma cells to cytotoxic killing through cell cycle–coupled loss of IRF4 by Huang, Xiangao, Di Liberto, Maurizio, Jayabalan, David, Liang, Jun, Ely, Scott, Bretz, Jamieson, Shaffer, Arthur L., Louie, Tracey, Chen, Isan, Randolph, Sophia, Hahn, William C., Staudt, Louis M., Niesvizky, Ruben, Moore, Malcolm A.S., Chen-Kiang, Selina

“…Dysregulation of cyclin-dependent kinase 4 (CDK4) and CDK6 by gain of function or loss of inhibition is common in human cancer, including multiple myeloma, but…”
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Management of Rapidly Progressing Periapical Pathologies: A Case Report by Croft, Kevin, Louie, Tracey, Colosi, Daniel C

“…Dentists often treat swellings from odontogenic periapical pathologies. One management option involves immediate treatment with antibiotics, followed by…”
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Management of rapidly progressing periopical pathologies: a case report by Croft, Kevin, Louie, Tracey, Colosi, Daniel C

“…Dentists often treat swellings from odontogenic periapical pathologies. One management option involves immediate treatment with antibiotics, followed by…”
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Selective Inhibition of CDK4 and CDK6 Primes Chemoresistant Myeloma Cell for Cytotoxic Killing through Induction of Cell Cycle-Coupled Mitochondrial Dysfunction and Apoptosis by Huang, Xiangao, Di Liberto, Maurizio, Louie, Tracey, Jayabalan, David S, Ely, Scott, Niesvizky, Ruben, Chen-Kiang, Selina

“…Dysregulation of cyclin-dependent kinase (CDK)4 or CDK6 activity by gain of function or loss of inhibition is one of the most frequent aberrations in cancer…”
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Targeting Cdk4/6 in Combination Therapy Overcomes Proteasome Inhibitor Resistance in Multiple Myeloma through Synergistic Mitochondria Depolarization by Huang, Xiangao, Louie, Tracey, Di Liberto, Maurizio, Rice, Jun, Jayabalan, David, Zhang, Kang, Palladino, Michael, Chen, Isan, Toogood, Peter, Niesvizky, Ruben, Moore, Malcolm A.S., Chen-Kiang, Selina

“…Deregulation of Cdk4 or Cdk6 is central to the loss of cell cycle control in cancer. In myeloma, over-expression of Cdk4-cyclin D1 or Cdk6-cyclin D2…”
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A Novel Orally Active Small Molecule Potently Induces G1 Arrest in Primary Myeloma Cells and Prevents Tumor Growth by Specific Inhibition of Cdk4/6 by Baughn, Linda B., Di Liberto, Maurizio, Wu, Kaida, Toogood, Peter, Louie, Tracey, Gottschalk, Rachel, Niesvizky, Ruben, Cho, Hearn J., Ely, Scott, Moore, Malcolm A.S., Chen-Kiang, Selina

“…Cell cycle deregulation is central to the initiation and fatality of multiple myeloma, the second most common hematopoietic cancer, although impaired apoptosis…”
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A Novel Orally Active Small Molecule Potently Induces G sub(1) Arrest in Primary Myeloma Cells and Prevents Tumor Growth by Specific Inhibition of Cyclin-Dependent Kinase 4/6 by Baughn, Linda B, Di Liberto, Maurizio, Wu, Kaida, Toogood, Peter L, Louie, Tracey, Gottschalk, Rachel, Niesvizky, Ruben, Cho, Hearn, Ely, Scott, Moore, Malcolm AS, Chen-Kiang, Selina

“…Cell cycle deregulation is central to the initiation and fatality of multiple myeloma, the second most common hematopoietic cancer, although impaired apoptosis…”
Get full text