Search Results - "Loughran, Kerry A"
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Effect of angiotensin receptor blockers and angiotensin‐converting enzyme 2 on plasma equilibrium angiotensin peptide concentrations in cats with heart disease
Published in Journal of veterinary internal medicine (01-01-2021)“…Background Little is known about the effect of renin angiotensin aldosterone system‐inhibiting (RAASi) drugs on alternative angiotensin peptides (APs) such as…”
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The use of focused cardiac ultrasound to screen for occult heart disease in asymptomatic cats
Published in Journal of veterinary internal medicine (01-09-2019)“…Background Focused cardiac ultrasound (FCU) helps detect occult heart disease in human patients. Hypothesis Focused cardiac ultrasound by a nonspecialist…”
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Effect of angiotensin receptor blockers and angiotensin converting enzyme 2 on plasma equilibrium angiotensin peptide concentrations in dogs with heart disease
Published in Journal of veterinary internal medicine (01-01-2021)“…Background The pathophysiology of heart failure involves maladaptive angiotensin peptides (APs) and enzymes, including angiotensin 2 (AT2) and angiotensin…”
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4
Metabolomics Analysis Reveals Deranged Energy Metabolism and Amino Acid Metabolic Reprogramming in Dogs With Myxomatous Mitral Valve Disease
Published in Journal of the American Heart Association (04-05-2021)“…Background Myxomatous mitral valve disease (MMVD), a naturally occurring heart disease, affects 10% to 15% of the canine population. Canine MMVD shares many…”
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Urine sodium concentration after intravenous furosemide in dogs with acute congestive heart failure and correlation with treatment efficacy
Published in Journal of veterinary internal medicine (01-01-2024)“…Background Poor natriuresis is a potential marker of diuretic resistance in dogs with acute congestive heart failure (CHF) but little is known about the…”
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Utility of focused cardiac ultrasonography training in veterinary students to differentiate stages of subclinical myxomatous mitral valve disease in dogs
Published in Journal of veterinary internal medicine (01-05-2024)“…Background Differentiation of the subclinical phases of myxomatous mitral valve disease (MMVD) in dogs relies heavily on echocardiography. Focused cardiac…”
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Plasma and tissue angiotensin‐converting enzyme 2 activity and plasma equilibrium concentrations of angiotensin peptides in dogs with heart disease
Published in Journal of veterinary internal medicine (01-07-2019)“…Background Angiotensin‐converting enzyme 2 (ACE2) is a homologue of angiotensin‐converting enzyme (ACE) and produces angiotensin peptides (APs), such as…”
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Gut Dysbiosis and Its Associations with Gut Microbiota-Derived Metabolites in Dogs with Myxomatous Mitral Valve Disease
Published in mSystems (20-04-2021)“…Gut dysbiosis and gut microbiota-derived metabolites, including bile acid (BA), short-chain fatty acid, and trimethylamine -oxide (TMAO), are associated with…”
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Circulating exosome microRNA associated with heart failure secondary to myxomatous mitral valve disease in a naturally occurring canine model
Published in Journal of extracellular vesicles (01-12-2017)“…Myxomatous mitral valve disease (MMVD) is functionally and histologically identical to mitral valve prolapse (MVP) in humans. Currently, there are no medical…”
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Comparative pathology of human and canine myxomatous mitral valve degeneration: 5HT and TGF-β mechanisms
Published in Cardiovascular pathology (01-05-2020)“…Myxomatous mitral valve degeneration (MMVD) is a leading cause of valve repair or replacement secondary to the production of mitral regurgitation, cardiac…”
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Echocardiographic indices and severity of mitral regurgitation in dogs with preclinical degenerative mitral valve disease
Published in Journal of veterinary internal medicine (01-03-2019)“…Background Describing severity of mitral regurgitation (MR) in dogs with degenerative mitral valve disease (DMVD) is challenging. Hypothesis/Objectives Mitral…”
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Observed and expected reliability of echocardiographic volumetric methods and critical change values for quantification of mitral regurgitant fraction in dogs
Published in Journal of veterinary internal medicine (27-09-2024)“…Reliability of echocardiographic calculations for stroke volume and mitral regurgitant fraction (RF ) are affected by observer variability and lack of a gold…”
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Prediction and measurement of diuretic responsiveness after oral administration of furosemide to healthy dogs and dogs with congestive heart failure
Published in Journal of veterinary internal medicine (01-11-2020)“…Background In human patients, cumulative urine volume (uVol) and urine sodium (uNa) can be predicted using spot urine samples and these quantitative measures…”
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Gut Dysbiosis and Its Associations with Gut Microbiota-Derived Metabolites in Dogs with Myxomatous Mitral Valve Disease
Published in mSystems (20-04-2021)“…Gut dysbiosis and gut microbiota-derived metabolites, including bile acid (BA), short-chain fatty acid, and trimethylamine N-oxide (TMAO), are associated with…”
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15
Reproducibility of geometric and flow-based echocardiographic measurements used for quantification of left ventricular total and forward stroke volume in healthy dogs
Published in Journal of veterinary cardiology (01-08-2020)“…Cardiac structure and function in dogs are commonly assessed using echocardiography. A variety of linear, area, and flow-based measurements can be used to…”
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