Search Results - "Loughney, Andrew"

Human Epidermal Neural Crest Stem Cells (hEPI-NCSC)—Characterization and Directed Differentiation into Osteocytes and Melanocytes by Clewes, Oliver, Narytnyk, Alla, Gillinder, Kevin R., Loughney, Andrew D., Murdoch, Alison P., Sieber-Blum, Maya

“…Here we describe the isolation, characterisation and ex-vivo expansion of human epidermal neural crest stem cells (hEPI-NCSC) and we provide protocols for…”
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The management of pregnancy in paroxysmal nocturnal haemoglobinuria on long term eculizumab by Kelly, Richard, Arnold, Louise, Richards, Stephen, Hill, Anita, Bomken, Charlotte, Hanley, John, Loughney, Andrew, Beauchamp, Jon, Khursigara, Gus, Rother, Russell P., Chalmers, Elizabeth, Fyfe, Andrew, Fitzsimons, Edward, Nakamura, Ryotaro, Gaya, Anna, Risitano, Antonio M., Schubert, Jörg, Norfolk, Derek, Simpson, Nigel, Hillmen, Peter

“…Summary In Paroxysmal nocturnal haemoglobinuria (PNH), pregnancy is associated with increased maternal and foetal complications to such an extent that the…”
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Emergency Caesarean Section: Influences on the Decision-to-Delivery Interval by Cerbinskaite, Aiste, Malone, Sarah, McDermott, Jennifer, Loughney, Andrew D.

“…RCOG/NICE guidelines recommend that, for fetal compromise in labour, delivery should be accomplished ideally within 30 minutes. In this study, we investigated…”
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Epigenetic modulation of the protein kinase A RIIα (PRKAR2A) gene by histone deacetylases 1 and 2 in human smooth muscle cells by Karolczak‐Bayatti, Magdalena, Loughney, Andrew D., Robson, Stephen C., Europe‐Finner, G. Nicholas

“…Recently we reported that the expression of the protein kinase A (PKA) regulatory subunit RIIα is dynamically regulated in human smooth muscle cells of the…”
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Internal podalic version with breech extraction by Webster, Sophia NE, Loughney, Andrew D

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Characterization of cellular retinoid-binding proteins in human myometrium during pregnancy by Tyson-Capper, Alison J., Cork, David M.W., Wesley, Emily, Shiells, Elizabeth A., Loughney, Andrew D.

“…Many complementary or competing signalling pathways bear an influence on the myometrium at any one time, and because the retinoic acid signalling pathway…”
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Recombinant Activated Factor VII (rFVIIa) in the Management of Major Obstetric Haemorrhage : A Case Series and a Proposed Guideline for Use by Bomken, Charlotte, Mathai, Sue, Biss, Tina, Loughney, Andrew D., Hanley, John

“…Major obstetric haemorrhage remains a significant cause of maternal morbidity and mortality. Previous case reports suggest the potential benefit of recombinant…”
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Group B streptococcal disease: screening and treatment in pregnancy by El Malek, Bassel Abd, Embleton, Nicholas D, Loughney, Andrew D

“…Specialist Registrar in Obstetrics and Gynaecology , Royal Victoria Infirmary, Newcastle upon Tyne, UK. Consultant in Neonatal Medicine , Royal Victoria…”
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Differentiation of Human Epidermal Neural Crest Stem Cells (hEPI-NCSC) into Virtually Homogenous Populations of Dopaminergic Neurons by Narytnyk, Alla, Verdon, Bernard, Loughney, Andrew, Sweeney, Michele, Clewes, Oliver, Taggart, Michael J., Sieber-Blum, Maya

“…Here we provide a protocol for the directed differentiation of hEPI-NCSC into midbrain dopaminergic neurons, which degenerate in Parkinson’s disease. hEPI-NCSC…”
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Human Epidermal Neural Crest Stem Cells (hEPI‐NCSC) by Sieber‐Blum, Maya, Clewes, Oliver, Loughney, Andrew, Murdoch, Alison

“…EPI‐NCSC originate from the embryonic neural crest and reside in a postnatal location, the bulge of hair follicles. Here we report the characterization and…”
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Characterization of human epidermal neural crest stem cell (hEPI‐NCSC) candidate cells by Gillinder, Kevin, Rajan, Neil, Loughney, Andrew, Murdoch, Alison, Sieber‐Blum, Maya

“…Abstract only We provide the first comprehensive characterization of hEPI‐NCSC candidate cells. Mouse EPI‐NCSC are multipotent remnants of the embryonic neural…”
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Nuclear retinoid receptor expression in normal human endometrium throughout the menstrual cycle by Kumarendran, M. Kumar, Loughney, Andrew D., Prentice, Andrew, Thomas, Eric J., Redfern, Christopher P.F.

“…Previous work has shown that retinoic acid receptors (RARs) and retinoid X receptors (RXRs) are expressed in human endometrial epithelial and stromal cells…”
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Successful Pregnancy Outcomes in Paroxysmal Nocturnal Hemoglobinuria with Long-Term Eculizumab Treatment by Kelly, Richard, Arnold, Louise, Richards, Stephen J., Hill, Anita, Bomken, Charlotte, Hanley, John, Loughney, Andrew, Khursigara, Gus, Rother, Russell P., Chalmers, Elizabeth, Fitzsimons, Edward, Nakamura, Ryotaro, Gaya, Anna, Rotoli, Bruno, Risitano, Antonio M., Schubert, Joerg, Hillmen, Peter

“…Paroxysmal nocturnal hemoglobinuria (PNH) is characterized by a lack of the terminal complement inhibitor CD59 on erythrocytes that renders these cells…”
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Birth before arrival at delivery suite: Associations and consequences by Loughney, Andrew, Collis, Rhona, Dastgir, Saleem

“…The objective of this cohort study was to identify factors associated with birth before arrival (BBA) at the delivery suite in women planning a hospital birth…”
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Authors' reply by Loughney, Andrew D., Embleton, Nick

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Authors' reply by Loughney, Andrew D., Embleton, Nick

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The Use of a Scoring System to Guide Thromboprophylaxis in a High-Risk Pregnant Population by Schoenbeck, D., Nicolle, A., Newbegin, K., Hanley, John, Loughney, Andrew D.

“…Guidelines for thromboprophylaxis in pregnancy are usually based upon clinical observations and expert opinion. For optimal impact, their use must be attended…”
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Cellular retinoid binding proteins and nuclear retinoic acid receptors in endometrial epithelial cells by Siddiqui, N A, Loughney, A, Thomas, E J, Dunlop, W, Redfern, C P

“…Retinoic acid, one of the most potent of the naturally occurring retinoids (retinol and derivatives), is required in vivo for the maintenance of epithelial…”
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Operative Obstetrics 2nd edition by Loughney, Andrew

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