Search Results - "Loughman, Anthony"

A Novel Staphylococcus aureus Biofilm Phenotype Mediated by the Fibronectin-Binding Proteins, FnBPA and FnBPB by O'Neill, Eoghan, Pozzi, Clarissa, Houston, Patrick, Humphreys, Hilary, Robinson, D Ashley, Loughman, Anthony, Foster, Timothy J, O'Gara, James P

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Both Complement- and Fibrinogen-Dependent Mechanisms Contribute to Platelet Aggregation Mediated by Staphylococcus aureus Clumping Factor B by MIAJLOVIC, Helen, LOUGHMAN, Anthony, BRENNAN, Marian, COX, Dermot, FOSTER, Timothy J

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Sequence diversity in the A domain of Staphylococcus aureus fibronectin-binding protein A by Loughman, Anthony, Sweeney, Tara, Keane, Fiona M, Pietrocola, Giampiero, Speziale, Pietro, Foster, Timothy J

“…Fibronectin-binding protein A (FnBPA) mediates adhesion of Staphylococcus aureus to fibronectin, fibrinogen and elastin. We previously reported that S. aureus…”
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Fibrinogen and elastin bind to the same region within the A domain of fibronectin binding protein A, an MSCRAMM of Staphylococcus aureus by Keane, Fiona M, Loughman, Anthony, Valtulina, Viviana, Brennan, Marian, Speziale, Pietro, Foster, Timothy J

“…The fibronectin binding protein, FnBPA, is a multifunctional microbial surface component recognizing adhesive matrix molecule (MSCRAMM) that promotes bacterial…”
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Molecular Basis for Staphylococcus aureus–Mediated Platelet Aggregate Formation Under Arterial Shear In Vitro by Kerrigan, Steven W, Clarke, Niamh, Loughman, Anthony, Meade, Gerardene, Foster, Timothy J, Cox, Dermot

“…OBJECTIVE—Staphylococcus aureus is the most frequent causative organism of infective endocarditis (IE) and is characterized by thrombus formation on a cardiac…”
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Fibronectin‐binding proteins of Staphylococcus aureus mediate activation of human platelets via fibrinogen and fibronectin bridges to integrin GPIIb/IIIa and IgG binding to the FcγRIIa receptor by Fitzgerald, J. Ross, Loughman, Anthony, Keane, Fiona, Brennan, Marian, Knobel, Morris, Higgins, Judy, Visai, Livia, Speziale, Pietro, Cox, Dermot, Foster, Timothy J.

“…Summary Staphylococcus aureus is a leading cause of infective endocarditis (IE). Platelet activation promoted by S. aureus resulting in aggregation and…”
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Roles for fibrinogen, immunoglobulin and complement in platelet activation promoted by Staphylococcus aureus clumping factor A by Loughman, Anthony, Fitzgerald, J. Ross, Brennan, Marian P., Higgins, Judy, Downer, Robert, Cox, Dermot, Foster, Timothy J.

“…Summary Staphylococcus aureus is an important cause of infective endocarditis (IE) in patients without a history of prior heart valve damage. The ability to…”
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Clumping factor A of Staphylococcus aureus inhibits phagocytosis by human polymorphonuclear leucocytes by Higgins, Judy, Loughman, Anthony, Van Kessel, Kok P.M., Van Strijp, Jos A.G., Foster, Timothy J.

“…Abstract Staphylococcus aureus is a major cause of nosocomial and community-acquired infection. It expresses several factors that promote avoidance of…”
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Capsular Polysaccharide Masks Clumping Factor A-Mediated Adherence of Staphylococcus aureus to Fibrinogen and Platelets by Risley, Allison L., Loughman, Anthony, Cywes-Bentley, Colette, Foster, Timothy J., Lee, Jean C.

“…Background. Clumping factor A (ClfA) is a Staphylococcus aureus cell wall-associated adhesin that mediates staphylococcal binding to fibrinogen and platelets…”
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Fibrinogen and elastin bind to the same region within the A domain of fibronectin binding protein A, an MSCRAMM of Staphylococcus aureus by Keane, Fiona M, Loughman, Anthony, Valtulina, Viviana, Brennan, Marian

“…The fibronectin binding protein, FnBPA, is a multifunctional microbial surface component recognizing adhesive matrix molecule (MSCRAMM) that promotes bacterial…”
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The Role of Staphylococcus aureus Adhesins in the Pathogenesis of Ventricular Assist Device–Related Infections by Arrecubieta, Carlos, Asai, Tomohiro, Bayern, Manuel, Loughman, Anthony, Fitzgerald, J. Ross, Shelton, Corbett E., Baron, Helen M., Dang, Nicholas C., Deng, Mario C., Naka, Yoshifumi, Foster, Timothy J., Lowy, Franklin D.

“…Ventricular assist devices (VADs) are an important form of therapy for end-stage congestive heart failure. However, infection of the VAD, which is often caused…”
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Fibronectin-binding proteins of Staphylococcus aureus mediate activation of human platelets via fibrinogen and fibronectin bridges to integrin GPIIb/IIIa and IgG binding to the Fc[gamma]RIIa receptor by J Ross Fitzgerald, Loughman, Anthony, Keane, Fiona, Brennan, Marian

“…Staphylococcus aureus is a leading cause of infective endocarditis (IE). Platelet activation promoted by S. aureus resulting in aggregation and thrombus…”
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Sequence diversity in the A domain of Staphylococcus aureusfibronectin-binding protein A by Loughman, Anthony, Sweeney, Tara, Keane, Fiona M, Pietrocola, Giampiero, Speziale, Pietro, Foster, Timothy J

“…Abstract Background Fibronectin-binding protein A (FnBPA) mediates adhesion of Staphylococcus aureus to fibronectin, fibrinogen and elastin. We previously…”
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Clumping factor A of Staphylococcus aureus inhibits phagocytosis by human polymorphonudear leucocytes by HIGGINS, Judy, LOUGHMAN, Anthony, VAN KESSEL, Kok P. M, VAN STRIJP, Jos A. G, FOSTER, Timothy J

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Fibronectin-binding proteins of Staphylococcus aureus mediate activation of human platelets via fibrinogen and fibronectin bridges to integrin GPIIb/IIIa and IgG binding to the FcgammaRIIa receptor by Fitzgerald, J Ross, Loughman, Anthony, Keane, Fiona, Brennan, Marian, Knobel, Morris, Higgins, Judy, Visai, Livia, Speziale, Pietro, Cox, Dermot, Foster, Timothy J

“…Staphylococcus aureus is a leading cause of infective endocarditis (IE). Platelet activation promoted by S. aureus resulting in aggregation and thrombus…”
Get full text