Search Results - "Loubidi, Mohammed"

Comparison of 2‑Aminopyridine and 4‑Thiopseudisocytosine PNA Nucleobases for Hoogsteen Recognition of Guanosine in RNA by Kumpina, Ilze, Loubidi, Mohammed, Rozners, Eriks

“…Peptide nucleic acid (PNA) is emerging as a promising ligand for triple-helical recognition of folded biologically relevant RNA. Chemical modifications are…”
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Synthesis of New Pyrazolo[3,4-d]pyrimidine Derivatives: NMR Spectroscopic Characterization, X-Ray, Hirshfeld Surface Analysis, DFT, Molecular Docking, and Antiproliferative Activity Investigations by El Hafi, Mohamed, Anouar, El Hassane, Lahmidi, Sanae, Boulhaoua, Mohammed, Loubidi, Mohammed, Alanazi, Ashwag S, Filali, Insaf, Hefnawy, Mohamed, El Ghayati, Lhoussaine, Mague, Joel T, Essassi, El Mokhtar

“…Four new pyrazolo[3,4-d]pyrimidines (P1–P4) were successfully synthesized in good relative yields by reacting…”
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Microwave-assisted acid-induced formation of linker vacancies within Zr-based metal organic frameworks with enhanced heterogeneous catalysis by Liang, Yu, Li, Chenhui, Chen, Lanjun, Huo, Jia, Loubidi, Mohammed, Zhou, Yangyang, Liu, Yanbo

“…Rich linker vacancies have been created within stable Zr-based metal-organic frameworks through a microwave-assisted acid-induced method, which demonstrate…”
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A Greener and Efficient Method for Nucleophilic Aromatic Substitution of Nitrogen-Containing Fused Heterocycles by Campos, Joana F, Loubidi, Mohammed, Scherrmann, Marie-Christine, Berteina-Raboin, Sabine

“…A simple and efficient methodology for the nucleophilic aromatic substitution of nitrogen-containing fused heterocycles with interesting biological activities…”
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First Metal-Free Synthesis of Tetracyclic Pyrido and Pyrazino Thienopyrimidinone Molecules by Aounzou, Mohammed, Campos, Joana F, Loubidi, Mohammed, Berteina-Raboin, Sabine

“…We report herein a new metal free synthetic pathway to generate tetracyclic compounds from 3-aminothieno[3,2- ]pyridine-2-carboxylate. To enlarge the molecular…”
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Pyrido[2′,1′:2,3]imidazo[4,5-c]isoquinolin-5-amines as Potential Cytotoxic Agents against Human Neuroblastoma by Tber, Zahira, Loubidi, Mohammed, Jouha, Jabrane, Hdoufane, Ismail, Erdogan, Mümin Alper, Saso, Luciano, Armagan, Güliz, Berteina-Raboin, Sabine

“…We report herein the evaluation of various pyrido[2′,1′:2,3]imidazo[4,5-c]isoquinolin-5-amines as potential cytotoxic agents. These molecules were obtained by…”
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Design, Synthesis, and Biological Evaluation of Novel Tomentosin Derivatives in NMDA-Induced Excitotoxicity by Zaki, Mohamed, Loubidi, Mohammed, Bilgiç, Tuğçe, Birim, Derviş, Akssira, Mohamed, Dagcı, Taner, Berteina-Raboin, Sabine, Saso, Luciano, Khouili, Mostafa, Armagan, Güliz

“…N-methyl-D-aspartate (NMDA) receptor stimulation may lead to excitotoxicity, which triggers neuronal death in brain disorders. In addition to current clinical…”
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Electrostatic Interaction-Induced Formation of Enzyme-on-MOF as Chemo-Biocatalyst for Cascade Reaction with Unexpectedly Acid-Stable Catalytic Performance by Tan, Wenlong, Wei, Ting, Huo, Jia, Loubidi, Mohammed, Liu, Tingting, Liang, Yu, Deng, Libo

“…Combining biocatalytic and chemocatalytic reactions in a one-pot reaction not only avoids the tedious isolation of intermediates during the reactions but also…”
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Increasing exposure of atomically dispersed Ni sites via constructing hierarchically porous supports for enhanced electrochemical CO2 reduction by Liu, Youzhen, Li, Chenhui, Loubidi, Mohammed, Wang, Dongdong, Zhou, Ling, Niu, Songyang, Liu, Qingquan, Huo, Jia

“…[Display omitted] •A facile strategy is developed for preparing atomically dispersed Ni sites.•Ni active sites can be fully exposed on hierarchically porous…”
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Synthesis of New Pyrazolo3,4-dpyrimidine Derivatives: NMR Spectroscopic Characterization, X-Ray, Hirshfeld Surface Analysis, DFT, Molecular Docking, and Antiproliferative Activity Investigations by El Hafi, Mohamed, Anouar, El Hassane, Lahmidi, Sanae, Boulhaoua, Mohammed, Loubidi, Mohammed, Alanazi, Ashwag S, Filali, Insaf, Hefnawy, Mohamed, El Ghayati, Lhoussaine, Mague, Joel T, Essassi, El Mokhtar

“…Four new pyrazolo[3,4-d]pyrimidines (P1-P4) were successfully synthesized in good relative yields by reacting…”
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Pd-catalyzed Suzuki/Sonogashira cross-coupling reaction and the direct sp3 arylation of 7-chloro-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidine by Loubidi, Mohammed, Moutardier, Anaïs, Campos, Joana F., Berteina-Raboin, Sabine

“…[Display omitted] •Heterocyclic nitrogen compounds.•Triazolo[1,5-a]pyrimidine synthesis.•Palladium cross-coupling.•Direct sp3 arylation. A rapid and efficient…”
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Synthesis of diverse isoxazolylamino-2-(aryl)acetamides using one-pot Multicomponent Reactions: X-ray, Hirshfeld analysis and DFT modeling by Loubidi, Mohammed, Jouha, Jabrane, Hdoufane, Ismail, El Hafi, Mohamed, Tber, Zahira, Cherqaoui, Driss, Mague, Joel T.

“…We report an efficient and rapid synthesis of several new N-(tert-butyl)-2-(isoxazol-3-ylamino)-2-(aryl)acetamide derivatives from the corresponding aldehydes…”
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Synthesis of new heterocyclic compounds based on pyrazolopyridine scaffold and evaluation of their neuroprotective potential in MPP+-induced neurodegeneration by Jouha, Jabrane, Loubidi, Mohammed, Bouali, Jamila, Hamri, Salha, Hafid, Abderrafia, Suzenet, Franck, Guillaumet, Gérald, Dagcı, Taner, Khouili, Mostafa, Aydın, Fadime, Saso, Luciano, Armagan, Güliz

“…Neurodegenerative disorders including Alzheimer's disease, Parkinson's disease, and Huntington's disease affect millions of people in the world. Thus several…”
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One‐Pot S N Ar/Direct Pd‐Catalyzed CH Arylation Functionalization of Pyrazolo[1,5‐ a ]pyrimidine at the C3 and C7 Positions by Loubidi, Mohammed, Manga, Catherine, Tber, Zahira, Bassoude, Ibtissam, Essassi, El Mokhtar, Berteina‐Raboin, Sabine

“…An efficient and original synthesis of various 3,7‐substituted pyrazolo[1,5‐ a ]pyrimidines is reported. First, a two‐step process by an S N Ar amination…”
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One‐Pot SNAr/Direct Pd‐Catalyzed CH Arylation Functionalization of Pyrazolo[1,5‐a]pyrimidine at the C3 and C7 Positions by Loubidi, Mohammed, Manga, Catherine, Tber, Zahira, Bassoude, Ibtissam, Essassi, El Mokhtar, Berteina‐Raboin, Sabine

“…An efficient and original synthesis of various 3,7‐substituted pyrazolo[1,5‐a]pyrimidines is reported. First, a two‐step process by an SNAr amination followed…”
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Efficient synthesis and first regioselective C-6 direct arylation of imidazo[2,1-c][1,2,4]triazine scaffold and their evaluation in H2O2-induced oxidative stress by Loubidi, Mohammed, Jouha, Jabrane, Tber, Zahira, Khouili, Mostafa, Suzenet, Franck, Akssira, Mohamed, Erdogan, Mümin Alper, Köse, Fadime Aydın, Dagcı, Taner, Armagan, Güliz, Saso, Luciano, Guillaumet, Gérald

“…Oxidative stress and apoptosis are both associated with various acute and chronic disorders. Thus, the aim of the present study is to synthesize…”
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Unusual rearrangement of imidazo[1,5-]imidazoles and imidazo[1,2-]pyrazoles into imidazo[1,5-]pyrimidines and pyrazolo[1,5-]pyrimidines by Gambouz, Khadija, Driowya, Mohsine, Loubidi, Mohammed, Tber, Zahira, Allouchi, Hassan, El Kazzouli, Saïd, Akssira, Mohamed, Guillaumet, Gérald

“…A multicomponent reaction giving easy and cheap access to a variety of bicyclic 5,5-fused hetero-rings has been developed. Then, an usual rearrangement of…”
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Efficient synthesis and first regioselective C-6 direct arylation of imidazo[2,1-c][1,2,4]triazine scaffold and their evaluation in H 2 O 2 -induced oxidative stress by Loubidi, Mohammed, Jouha, Jabrane, Tber, Zahira, Khouili, Mostafa, Suzenet, Franck, Akssira, Mohamed, Erdogan, Mümin Alper, Köse, Fadime Aydın, Dagcı, Taner, Armagan, Güliz, Saso, Luciano, Guillaumet, Gérald

“…Oxidative stress and apoptosis are both associated with various acute and chronic disorders. Thus, the aim of the present study is to synthesize…”
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Design, Synthesis, Cytotoxic Effect Evaluation and Molecular Docking of (R)‐Camphor‐Based Thiazolidinone‐Isoxazole and Thiazolidinone‐1,2,3‐triazole Hybrids by Ousidi, Abdellah N'ait, Bimoussa, Abdoullah, Loubidi, Mohammed, Fawzi, Mourad, Laamari, Yassine, Oubella, Ali, Maatallah, Mohamed, Berteina‐Raboin, Sabine, Auhmani, Aziz, Taha, Mohamed Labd, Morjani, Hamid, Ait Itto, Moulay Youssef

“…A variety of hybrid compounds, combining a camphor thiazolidinone skeleton with either 1,2,3‐triazole or isoxazole nucleus, have been synthesized from natural…”
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