Search Results - "Lou, Yazhou"

Distal Ionic Substrate–Catalyst Interactions Enable Long-Range Stereocontrol: Access to Remote Quaternary Stereocenters through a Desymmetrizing Suzuki–Miyaura Reaction by Lou, Yazhou, Wei, Junqiang, Li, Mingfeng, Zhu, Ye

“…Spatial distancing of a substrate’s reactive group and nonreactive catalyst-binding group from its pro-stereogenic element presents substantial hurdles in…”
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Copper-Catalyzed Enantioselective 1,6-Boration of para-Quinone Methides and Efficient Transformation of gem-Diarylmethine Boronates to Triarylmethanes by Lou, Yazhou, Cao, Peng, Jia, Tao, Zhang, Yongling, Wang, Min, Liao, Jian

“…Presented is the first enantioselective copper‐catalyzed 1,6‐conjugate addition of bis(pinacolato)diboron to para‐quinone methides. The reaction proceeds with…”
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A Cu/Pd Cooperative Catalysis for Enantioselective Allylboration of Alkenes by Jia, Tao, Cao, Peng, Wang, Bing, Lou, Yazhou, Yin, Xuemei, Wang, Min, Liao, Jian

“…A cooperative Cu/Pd-catalyzed asymmetric three-component reaction of styrenes, B2(pin)2, and allyl carbonates was reported. This reaction, in the presence of…”
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Dynamic Kinetic Asymmetric Reductive Amination: Synthesis of Chiral Primary β‐Amino Lactams by Lou, Yazhou, Hu, Yutao, Lu, Jiaxiang, Guan, Fanfu, Gong, Gelin, Yin, Qin, Zhang, Xumu

“…A highly efficient ruthenium‐catalyzed asymmetric reductive amination (ARA) of racemic β‐keto lactams with molecular hydrogen and ammonium salts is disclosed…”
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Copper(I)-Catalyzed Asymmetric Pinacolboryl Addition of N‑Boc-imines Using a Chiral Sulfoxide–Phosphine Ligand by Wang, Ding, Cao, Peng, Wang, Bing, Jia, Tao, Lou, Yazhou, Wang, Min, Liao, Jian

“…Highly efficient and enantioselective copper­(I)-catalyzed pinacolboryl addition of N-Boc-imines is reported. By using a single chiral…”
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Copper-Catalyzed Asymmetric Three-Component Borylstannation: Enantioselective Formation of CSn Bond by Jia, Tao, Cao, Peng, Wang, Ding, Lou, Yazhou, Liao, Jian

“…In summary, a first copper‐catalyzed synthesis of α‐aryl‐β‐borylstannane compounds was accomplished through three‐component borylstannation of aryl‐substituted…”
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Catalytic asymmetric hydrogenation of ()-α-dehydroamido boronate esters: direct route to alkyl-substituted α-amidoboronic esters by Lou, Yazhou, Wang, Jun, Gong, Gelin, Guan, Fanfu, Lu, Jiaxiang, Wen, Jialin, Zhang, Xumu

“…The direct catalytic asymmetric hydrogenation of ( Z )-α-dehydroamino boronate esters was realized. Using this approach, a class of therapeutically relevant…”
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Dynamic Kinetic Asymmetric Reductive Amination: Synthesis of Chiral Primary β‐Amino Lactams by Lou, Yazhou, Hu, Yutao, Lu, Jiaxiang, Guan, Fanfu, Gong, Gelin, Yin, Qin, Zhang, Xumu

“…A highly efficient ruthenium‐catalyzed asymmetric reductive amination (ARA) of racemic β‐keto lactams with molecular hydrogen and ammonium salts is disclosed…”
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Copper-Catalyzed Enantioselective 1,6-Boration of para-Quinone Methides and Efficient Transformation of gem-Diarylmethine Boronates to Triarylmethanes by Lou, Yazhou, Cao, Peng, Jia, Tao, Zhang, Yongling, Wang, Min, Liao, Jian

“…Presented is the first enantioselective copper‐catalyzed 1,6‐conjugate addition of bis(pinacolato)diboron to para‐quinone methides. The reaction proceeds with…”
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Hydrogen-Bond-Promoted Palladium Catalysis: Allylic Alkylation of Indoles with Unsymmetrical 1,3-Disubstituted Allyl Acetates Using Chiral Bis(sulfoxide) Phosphine Ligands by Du, Le, Cao, Peng, Xing, Junwei, Lou, Yazhou, Jiang, Liyin, Li, Liangchun, Liao, Jian

“…A DYKAT die hard: A new class of chiral BiSO‐P ligands were effective for an unprecedented palladium‐catalyzed asymmetric allylic alkylation of indoles with…”
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Enantioselective Synthesis of Chiral 1,4-Enynes via Palladium-Catalyzed Branch-Selective Allylic C–H Alkylation by Lou, Yazhou, Lin, Zihan, Wu, Chenxi, Nong, Zhong-Sheng, Liu, Rui, Gong, Liu-Zhu

“…We herein present the construction of a chiral 1,4-enyne featuring tertiary or quaternary stereogenic center via Pd-catalyzed branch-, enantio-, and…”
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Regio- and Stereoselective Hydrochlorination/Cyclization of 1,n‑Enynes by FeCl3 Catalysis by Hou, Jicheng, Yin, Junhao, Han, Hao, Yang, Qirui, Li, Yougui, Lou, Yazhou, Wu, Xiang, You, Yang’en

“…A highly regio- and stereoselective hydrochlorination/cyclization of enynes has been reported by FeCl3 catalysis. A variety of enynes undergo this cyclization…”
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A Scalable and Metal-Free Synthesis of Indazoles from 2‑Aminophenones and In Situ Generated De-Boc-Protected O‑Mesitylsulfonyl Hydroxylamine Derivatives by Wang, Jinlong, Shi, Dongmin, Wang, Zihao, Ren, Fucai, Li, Xin, You, Yang’en, Liu, Xinhua, Lou, Yazhou

“…A one-pot metal-free protocol to access indazoles from easily available 2-aminophenones and hydroxylamine derivatives has been achieved. The reaction is…”
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Regio- and Stereoselective Hydrochlorination/Cyclization of 1, n -Enynes by FeCl 3 Catalysis by Hou, Jicheng, Yin, Junhao, Han, Hao, Yang, Qirui, Li, Yougui, Lou, Yazhou, Wu, Xiang, You, Yang'en

“…A highly regio- and stereoselective hydrochlorination/cyclization of enynes has been reported by FeCl catalysis. A variety of enynes undergo this cyclization…”
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Copper-Catalyzed Asymmetric Three-Component Borylstannation: Enantioselective Formation of CSn Bond by Jia, Tao, Cao, Peng, Wang, Ding, Lou, Yazhou, Liao, Jian

“…In summary, a first copper-catalyzed synthesis of [alpha]-aryl-[beta]-borylstannane compounds was accomplished through three-component borylstannation of…”
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A step-wise reduction of nonracemic α-ketoamides to α-methine amides under mild conditions by Wang, Bing, Wang, Min, Jia, Tao, Lou, Yazhou, Liao, Jian, Cao, Peng

“…A step-wise reductive method that converts nonracemic γ-chiral α-ketoamides into amide derivatives was developed under mild conditions. The method involves a…”
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Hydrogen-Bond-Promoted Palladium Catalysis: Allylic Alkylation of Indoles with Unsymmetrical 1,3-Disubstituted Allyl Acetates Using Chiral Bis(sulfoxide) Phosphine Ligands by Du, Le, Cao, Peng, Xing, Junwei, Lou, Yazhou, Jiang, Liyin, Li, Liangchun, Liao, Jian

“…Unsymmetrisch/asymmetrisch: Neuartige chirale BiSO‐P‐Liganden erwiesen sich als wirksam in der Palladium‐katalysierten asymmetrischen allylischen Alkylierung…”
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