Search Results - "Lou, Hongxiang"

Practical and Highly Selective CH Functionalization of Structurally Diverse Ethers by Wan, Miao, Meng, Zhilin, Lou, Hongxiang, Liu, Lei

“…A trityl ion mediated CH functionalization of ethers with a wide range of nucleophiles at ambient temperature has been developed. The reaction displays high…”
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Dietary Polyphenols and Their Biological Significance by Han, Xiuzhen, Shen, Tao, Lou, Hongxiang

“…Dietary polyphenols represent a wide variety of compounds that occur in fruits,vegetables, wine, tea, extra virgin olive oil, chocolate and other cocoa…”
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Current drug research on PEGylation with small molecular agents by Li, Wenjun, Zhan, Peng, De Clercq, Erik, Lou, Hongxiang, Liu, Xinyong

“…PEGylation, covalent attaching polyethylene glycol (PEG) polymers to therapeutic agents, is one of the most promising techniques to improve the therapeutic…”
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The PI3K/AKT Pathway and Renal Cell Carcinoma by Guo, Huifang, German, Peter, Bai, Shanshan, Barnes, Sean, Guo, Wei, Qi, Xiangjie, Lou, Hongxiang, Liang, Jiyong, Jonasch, Eric, Mills, Gordon B., Ding, Zhiyong

“…The phosphatidylinositol 3 kinase （PI3K）/AKT pathway is genetically targeted in more pathway components and in more tumor types than any other growth factor…”
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Anti-inflammatory activities and potential mechanisms of phenolic acids isolated from Salvia miltiorrhiza f. alba roots in THP-1 macrophages by Liu, Haimei, Ma, Shuli, Xia, Hongrui, Lou, Hongxiang, Zhu, Faliang, Sun, Longru

“…The roots of Salvia miltiorrhiza f. alba (Lamiaceae) (RSMA) are used as the Danshen, a traditional Chinese medicine, to treat the vascular diseases at local…”
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Evaluation of the anti-inflammatory activities of tanshinones isolated from Salvia miltiorrhiza var. alba roots in THP-1 macrophages by Ma, Shuli, Zhang, Dawei, Lou, Hongxiang, Sun, Longru, Ji, Jianbo

“…Salvia miltiorrhiza var. alba roots are used as the Chinese traditional medicine Danshen for the treatment of cardiovascular diseases in local clinical…”
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Efflux pump-mediated resistance to antifungal compounds can be prevented by conjugation with triphenylphosphonium cation by Chang, Wenqiang, Liu, Jun, Zhang, Ming, Shi, Hongzhuo, Zheng, Sha, Jin, Xueyang, Gao, Yanhui, Wang, Shuqi, Ji, Aiguo, Lou, Hongxiang

“…Antifungal resistance due to upregulation of efflux pumps is prevalent in clinical Candida isolates. Potential efflux pump substrates (PEPSs), which are active…”
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Enhancement of oral absorption of curcumin by self-microemulsifying drug delivery systems by Cui, Jing, Yu, Bo, Zhao, Yu, Zhu, Weiwei, Li, Houli, Lou, Hongxiang, Zhai, Guangxi

“…Curcumin is a poorly water-soluble drug and its oral bioavailability is very low. A new self-microemulsifying drug delivery system (SMEDDS) has been…”
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Neuroprotective effects of linarin through activation of the PI3K/Akt pathway in amyloid-β-induced neuronal cell death by Lou, Haiyan, Fan, Peihong, Perez, Ruth G., Lou, Hongxiang

“…Linarin is a natural acetylcholinesterase inhibitor and the present study explored the neuroprotective effects against Aβ 25–35-induced neurotoxicity in…”
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Diorcinol D Exerts Fungicidal Action against Candida albicans through Cytoplasm Membrane Destruction and ROS Accumulation by Li, Ying, Chang, Wenqiang, Zhang, Ming, Li, Xiaobin, Jiao, Yang, Lou, Hongxiang

“…Candida albicans, which is the most common human fungal pathogen, causes high mortality among immunocompromised patients. Antifungal drug resistance becomes a…”
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Enhancement of gastrointestinal absorption of quercetin by solid lipid nanoparticles by Li, HouLi, Zhao, XiaoBin, Ma, YuKun, Zhai, GuangXi, Li, LingBing, Lou, HongXiang

“…The aim of the present study is to design and characterize quercetin-loaded solid lipid nanoparticles (QT-SLNs), clarify the absorption mechanism of QT-SLNs…”
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ent-Kaurane diterpenoids induce apoptosis and ferroptosis through targeting redox resetting to overcome cisplatin resistance by Sun, Yong, Qiao, Yanan, Liu, Yue, Zhou, Jinchuan, Wang, Xue, Zheng, Hongbo, Xu, Zejun, Zhang, Jiaozhen, Zhou, Yi, Qian, Lilin, Zhang, Chunyang, Lou, Hongxiang

“…Reactive oxygen species (ROS) induction is an effective mechanism to kill cancer cells for many chemotherapeutics, while resettled redox homeostasis induced by…”
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Bexarotene nanocrystal—Oral and parenteral formulation development, characterization and pharmacokinetic evaluation by Chen, Lijiang, Wang, Yongjie, Zhang, Jiaozhen, Hao, Leilei, Guo, Hejian, Lou, Hongxiang, Zhang, Dianrui

“…Bexarotene (Targretin®) is a synthetic retinoid that selectively activates the retinoid X receptor subfamily of retinoid receptors and exhibits potent…”
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MFSD7C protects hemolysis-induced lung impairments by inhibiting ferroptosis by Wang, Huirui, You, Xiaona, Wang, Jingcheng, Chen, Xinyi, Gao, Yinghui, Wang, Mengmeng, Zhang, Wenru, Zhang, Jiaozhen, Yu, Yang, Han, Bo, Qi, Mei, Liu, Xiaohui, Lou, Hongxiang, Dong, Ting

“…Hemolysis drives susceptibility to lung injury and predicts poor outcomes in diseases, such as malaria and sickle cell disease (SCD). However, the underlying…”
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Endolichenic Fungi: A Promising Medicinal Microbial Resource to Discover Bioactive Natural Molecules-An Update by Zhang, Wenge, Ran, Qian, Li, Hehe, Lou, Hongxiang

“…Lichens are some of the most unique fungi and are naturally encountered as symbiotic biological organisms that usually consist of fungal partners (mycobionts)…”
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Erg6 Acts as a Downstream Effector of the Transcription Factor Flo8 To Regulate Biofilm Formation in Candida albicans by Jin, Xueyang, Luan, Xiaoyi, Xie, Fei, Chang, Wenqiang, Lou, Hongxiang

“…The yeast-to-hyphal morphotype transition and subsequent biofilm formation are important virulence factors of Candida albicans and are closely associated with…”
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Synthesis and Biological Evaluation of Curcumin Derivatives with Water-Soluble Groups as Potential Antitumor Agents: An in Vitro Investigation Using Tumor Cell Lines by Ding, Luyang, Ma, Shuli, Lou, Hongxiang, Sun, Longru, Ji, Mei

“…Three series of curcumin derivatives including phosphorylated, etherified, and esterified products of curcumin were synthesized, and their anti-tumor…”
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Hemp (Cannabis sativa L.) Seed Phenylpropionamides Composition and Effects on Memory Dysfunction and Biomarkers of Neuroinflammation Induced by Lipopolysaccharide in Mice by Zhou, Yuefang, Wang, Shanshan, Ji, Jianbo, Lou, Hongxiang, Fan, Peihong

“…Hempseed has achieved a growing popularity in human nutrition, particularly regarding essential amino acids and fatty acids. The multiple positive attributes…”
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Grape Seed Polyphenols Protect Cardiac Cells from Apoptosis via Induction of Endogenous Antioxidant Enzymes by Du, Yu, Guo, Huaifang, Lou, Hongxiang

“…Grape seed extract (GSE) has been reported to exert protective effects on various forms of cardiac disorders. The cardiovascular protective effects of GSE are…”
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Retigeric acid B attenuates the virulence of Candida albicans via inhibiting adenylyl cyclase activity targeted by enhanced farnesol production by Chang, Wenqiang, Li, Ying, Zhang, Li, Cheng, Aixia, Lou, Hongxiang

“…Candida albicans, the most prevalent fungal pathogen, undergoes yeast-to-hyphal switch which has long been identified as a key fungal virulence factor. We…”
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