Search Results - "Lou, Chenghua"

Long Non-Coding RNA AGAP2-AS1 : A Comprehensive Overview on Its Biological Functions and Clinical Significances in Human Cancers by Ma, Feng, Zhang, Bingbing, Wang, Yiqi, Lou, Chenghua

“…Long non-coding RNAs (lncRNAs) are well known for their oncogenic or anti-oncogenic roles in cancer development. , a new lncRNA, has been extensively…”
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Long non-coding RNA MAFG-AS1: A promising therapeutic target for human cancers by Huang, Zhiyu, Zhang, Maoqing, Li, Jiayue, Lou, Chenghua

“…Long non-coding RNAs (lncRNAs) are commonly known for their important characters in cancer progression. LncRNA MAFG-antisense 1 (AS1) (MAFG-AS1) has been…”
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Alisol A Suppresses Proliferation, Migration, and Invasion in Human Breast Cancer MDA-MB-231 Cells by Lou, Chenghua, Xu, Xintong, Chen, Yan, Zhao, Huajun

“…Natural products are a precious source of promising leads for the development of novel cancer therapeutics. Recently, triterpenoids in Alismatis rhizoma has…”
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The beneficial pharmacological effects and potential mechanisms of picroside II: Evidence of its benefits from in vitro and in vivo by Ma, Shangying, Wang, Xueyi, Lai, Feifan, Lou, Chenghua

“…[Display omitted] •PII showed therapeutic potential in prevention and treatment of I/R injury, liver damage, inflammation and cancer.•Various biological…”
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Synergistic therapeutic potential of alpelisib in cancers (excluding breast cancer): Preclinical and clinical evidences by Ye, Yuhao, Huang, Zhiyu, Zhang, Maoqing, Li, Jiayue, Zhang, Yiqiong, Lou, Chenghua

“…The phosphoinositide 3-kinase (PI3K) signaling pathway is well-known for its important role in cancer growth, proliferation and migration. The activation of…”
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F1012‐2 inhibits the growth of triple negative breast cancer through induction of cell cycle arrest, apoptosis, and autophagy by Tian, Shasha, Chen, Yan, Yang, Bo, Lou, Chenghua, Zhu, Rui, Zhao, Yaping, Zhao, Huajun

“…Sesquiterpene lactones (SLs) are plant‐derived constituents that have been proved to have potential antitumour activity. However, the intracellular molecular…”
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Eupalinolide J induces apoptosis, cell cycle arrest, mitochondrial membrane potential disruption and DNA damage in human prostate cancer cells by Wu, Zeqi, Xu, Xintong, Dai, Lingjie, Wang, Yiqi, Yang, Bo, Zhao, Huajun, Lou, Chenghua

“…Eupalinolide J (EJ) is a new sesquiterpene lactone isolated from Eupatorium lindleyanum DC. In the present study, we investigated the anti-cancer activity of…”
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Picroside II, an iridoid glycoside from Picrorhiza kurroa, suppresses tumor migration, invasion, and angiogenesis in vitro and in vivo by Lou, Chenghua, Zhu, Zhihui, Xu, Xintong, Zhu, Rui, Sheng, Yunjie, Zhao, Huajun

“…[Display omitted] •PII inhibited the migration and invasion of MDA-MB-231 breast cancer cells both in vitro and in vivo.•PII inhibited the activity and…”
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Traditional Applications, Phytochemistry, and Pharmacological Activities of Eupatorium lindleyanum DC.: A Comprehensive Review by Wang, Xueyi, Ma, Shangying, Lai, Feifan, Wang, Yiqi, Lou, Chenghua

“…DC. (EL) has a long history of traditional use in China to cure coughs, chronic bronchitis, lobar pneumonia, and hypertension. Because of this extensive use of…”
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Selective anticancer activity of hirsutine against HER2-positive breast cancer cells by inducing DNA damage by LOU, CHENGHUA, YOKOYAMA, SATORU, SAIKI, IKUO, HAYAKAWA, YOSHIHIRO

“…Hirsutine is one of the major alkaloids isolated from plants of the Uncaria genus and is known for its cardioprotective, anti-hypertensive and anti-arrhythmic…”
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Eupalinolide J Suppresses the Growth of Triple-Negative Breast Cancer Cells via Targeting STAT3 Signaling Pathway by Lou, Chenghua, Chen, Yan, Zhang, Jie, Yang, Bo, Zhao, Huajun

“…Persistent activation of STAT3 plays an important role in the development of triple-negative breast cancer (TNBC), and suppression of STAT3 is considered as a…”
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Stephanthraniline A suppresses proliferation of HCT116 human colon cancer cells through induction of caspase-dependent apoptosis, dysregulation of mitochondrial function, cell cycle arrest and regulation of Akt/p38 signaling pathways by Wang, Lu, Yao, Li, Li, Xiaoyu, Chen, Juan, Lou, Chenghua, Wang, Yiqi

“…Stephanthraniline A (STA) is a C21 steroidal aglycone isolated from the stem of Stephanotis mucronata (Blanco) Merr. that exerts growth inhibition in human…”
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Anticancer properties of 10-hydroxycamptothecin in a murine melanoma pulmonary metastasis model in vitro and in vivo by Hu, Wei, Zhang, Chao, Fang, Yun, Lou, Chenghua

“…Lung cancer, including lung metastatic cancer, remains one of the most difficult types of cancer to treat. Therefore, the search for new agents for its…”
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Surface laser alloying of 17-4PH stainless steel steam turbine blades by Yao, Jianhua, Wang, Liang, Zhang, Qunli, Kong, Fanzhi, Lou, Chenghua, Chen, Zhijun

“…As a known high-quality precipitation hardening stainless steel with high strength, high antifatigue, excellent corrosion resistance and good weldability,…”
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2′,4′-Dihydroxychalcone-induced apoptosis of human gastric cancer MGC-803 cells via down-regulation of survivin mRNA by Lou, Chenghua, Yang, Guangming, Cai, Hao, Zou, Mingchang, Xu, Zisheng, Li, Yu, Zhao, Fengming, Li, Weidong, Tong, Li, Wang, Mingyan, Cai, Baochang

“…2′,4′-Dihydroxychalcone (TFC), a main component in Herba Oxytropis, is grouped under flavonoids, which are well known to have antitumor activities in vitro. In…”
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Sanmiao wan alleviates inflammation and exhibits hypouricemic effect in an acute gouty arthritis rat model by Wang, Xiaoqian, Sheng, Yunjie, Guan, Jiaqi, Zhang, Fengling, Lou, Chenghua

“…Sanmiao wan (SMW), a classical traditional Chinese medicine (TCM) formula, has been employed to treat gouty diseases in clinic as early as Yuan dynasty. It…”
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Arctigenin, a lignan from Arctium lappa L., inhibits metastasis of human breast cancer cells through the downregulation of MMP-2/−9 and heparanase in MDA-MB-231 cells by Lou, Chenghua, Zhu, Zhihui, Zhao, Yaping, Zhu, Rui, Zhao, Huajun

“…Arctigenin is a bioactive lignan isolated from the seeds of Arctium lappa L. which has been widely used as a diuretic and a diaphoretic in Traditional Chinese…”
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Identification of Hirsutine as an anti-metastatic phytochemical by targeting NF-κB activation by LOU, CHENGHUA, TAKAHASHI, KEI, IRIMURA, TATSURO, SAIKI, IKUO, HAYAKAWA, YOSHIHIRO

“…Nuclear factor-κB (NF-κB) activation has been implicated not only in carcinogenesis but also in cancer cell invasion and metastatic process; therefore,…”
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Eupalinolide O, a novel sesquiterpene lactone from Eupatorium lindleyanum DC., induces cell cycle arrest and apoptosis in human MDA-MB-468 breast cancer cells by Yang, Bo, Zhao, Yaping, Lou, Chenghua, Zhao, Huajun

“…Sesquiterpene lactones have been confirmed to have potential antitumor activity. Here, we demonstrated that Eupalinolide O (EO), a novel sesquiterpene lactone…”
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ZFP403, a novel tumor suppressor, inhibits the proliferation and metastasis in ovarian cancer by Zhu, Zhihui, Lou, Chenghua, Zheng, Zhiguo, Zhu, Rui, Tian, Shasha, Xie, Chengying, Zhao, Huajun

“…Zinc finger protein 403 (ZFP403) is located on human chromosome 17q12-21, the most common loss of heterozygosity regions for some oncogenes. However, the…”
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