Search Results - "Lotz, Gábor"
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1
Primary and secondary clarithromycin resistance in Helicobacter pylori and mathematical modeling of the role of macrolides
Published in Nature communications (15-04-2021)“…Clarithromycin is a macrolide antibiotic widely used for eradication of Helicobacter pylori infection, and thus resistance to this antibiotic is a major cause…”
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2
Immunomodulatory role of Parkinson’s disease 7 in inflammatory bowel disease
Published in Scientific reports (16-07-2021)“…Recently the role of Parkinson’s disease 7 (PARK7) was studied in gastrointestinal diseases, however, the complex role of PARK7 in the intestinal inflammation…”
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3
Claudin-18 expression in oesophagogastric adenocarcinomas: a tissue microarray study of 523 molecularly profiled cases
Published in British journal of cancer (30-07-2019)“…Background Claudin-18 (CLDN18) is a highly specific tight junction protein of the gastric mucosa. An isoform of CLDN18, the Claudin 18.2, has recently emerged…”
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4
Cross-testing of major molecular markers indicates distinct pathways of tumorigenesis in gastric adenocarcinomas and synchronous gastrointestinal stromal tumors
Published in Scientific reports (17-12-2020)“…Small subtype of the gastrointestinal stromal tumor (micro-GIST, MG) is usually asymptomatic and is frequently found incidentally in association with gastric…”
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5
Autophagy activity in cholangiocarcinoma is associated with anatomical localization of the tumor
Published in PloS one (15-06-2021)“…The presence of autophagy has been indicated in cholangiocarcinoma (CC), which disease has poor prognosis and limited treatment options. Recently, CC has been…”
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6
Microsatellite instability and mismatch repair protein deficiency: equal predictive markers?
Published in Pathology oncology research (09-04-2024)“…Current clinical guidelines recommend mismatch repair (MMR) protein immunohistochemistry (IHC) or molecular microsatellite instability (MSI) tests as…”
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Comment on Skrebinska et al. Who Could Be Blamed in the Case of Discrepant Histology and Serology Results for Helicobacter pylori Detection? Diagnostics 2022, 12, 133
Published in Diagnostics (Basel) (09-06-2022)“…In their article, Skebrinska and colleagues analysed the potential pitfalls of detecting Helicobacter pylori (H. pylori) by serology, histological (Giemsa) and…”
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8
Helicobacter pylori heteroresistance to clarithromycin in adults—New data by in situ detection and improved concept
Published in Helicobacter (Cambridge, Mass.) (01-02-2020)“…Background Clarithromycin (Cla) heteroresistance of Helicobacter pylori (H pylori) infections is commonly assessed by comparing the resistance status of antrum…”
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9
Prognostic Ability of Tumor Budding Outperforms Poorly Differentiated Clusters in Gastric Cancer
Published in Cancers (28-09-2022)“…The prognostic value of histological phenomena tumor budding (TB) and poorly differentiated clusters (PDCs) have been less studied in gastric cancer (GAC) and…”
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10
Sterile, abscess-like cerebral lesion during trastuzumab therapy after HER2 status switch in a triple negative breast cancer patient: a case report and literature review
Published in BMC cancer (01-07-2020)“…Breast cancer is a global health problem - it is the most common malignancy among women. Triple negative breast cancers (TNBC) account for 10-20% of female…”
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11
Proteome alterations in human autopsy tissues in relation to time after death
Published in Cellular and molecular life sciences : CMLS (01-05-2023)“…Protein expression is a primary area of interest for routine histological diagnostics and tissue-based research projects, but the limitations of its…”
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12
Local Invasion Patterns Characterized by SARIFA and Tumor Budding Differ and Have Distinct Prognostic Significance in Esophageal Adenocarcinoma and Squamous Cell Carcinoma
Published in Cancers (13-09-2024)“…Both esophageal squamous cell carcinoma (ESQCC) and adenocarcinoma (EAC) are known to have poor prognosis. We aimed to investigate the invasion front areas of…”
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13
Liver alterations and detection of SARS-CoV-2 RNA and proteins in COVID-19 autopsies
Published in GeroScience (01-04-2023)“…The most severe alterations in Coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome Coronavirus-2 (SARS-CoV-2) infection are…”
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14
Sensitivity of Helicobacter pylori detection by Giemsa staining is poor in comparison with immunohistochemistry and fluorescent in situ hybridization and strongly depends on inflammatory activity
Published in Helicobacter (Cambridge, Mass.) (01-08-2017)“…Background Conventional stainings (including H&E and special stains like Giemsa) are the most widely applied histopathologic detection methods of Helicobacter…”
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15
A COVID-19-association-dependent categorization of death causes in 100 autopsy cases
Published in GeroScience (01-10-2021)“…From March through December 2020, 100 autopsies were performed (Semmelweis University, Budapest, Hungary), with chart review, of patients with severe acute…”
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16
Neural elements behind the hepatoprotection of remote perconditioning
Published in The Journal of surgical research (01-02-2015)“…Abstract Background The ability of remote ischemic perconditioning (RIPER) to protect the liver from ischemic–reperfusion (IR) injury has been reported before;…”
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17
Attenuated isolated 3’ signal: A highly challenging therapy relevant ALK FISH pattern in NSCLC
Published in Lung cancer (Amsterdam, Netherlands) (01-05-2020)“…•We show cases featured with a unique massive reduction of the 3′ ALK FISH signal.•This therapy relevant pattern (termed downstream deletion) can be easily…”
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Autopsy findings in cancer patients infected with SARS-CoV-2 show a milder presentation of COVID-19 compared to non-cancer patients
Published in GeroScience (30-04-2024)“…COVID-19, caused by SARS-CoV-2, manifests with differing severity across distinct patient subgroups, with outcomes influenced by underlying comorbidities such…”
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19
Distinct Claudin Expression Profiles of Hepatocellular Carcinoma and Metastatic Colorectal and Pancreatic Carcinomas
Published in The journal of histochemistry and cytochemistry (01-04-2013)“…Tight junction proteins, including claudins, are often dysregulated during carcinogenesis and tumor progression. Moreover, the claudin expression pattern…”
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20
Addition of Chromosome 17 Polysomy and HER2 Amplification Status Improves the Accuracy of Clinicopathological Factor-Based Progression Risk Stratification and Tumor Grading of Non-Muscle-Invasive Bladder Cancer
Published in Cancers (21-09-2022)“…Progression of non-muscle-invasive bladder cancer (NMIBC) to muscle-invasive disease (MIBC) significantly worsens life expectancy. Its risk can be assessed by…”
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