Search Results - "Lotti, Lavinia V."
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JNK and macroautophagy activation by bortezomib has a pro-survival effect in primary effusion lymphoma cells
Published in PloS one (26-09-2013)“…Understanding the mechanisms of autophagy induction and its role during chemotherapeutic treatments is of fundamental importance in order to manipulate it to…”
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Phospholipases C and A2 control lysosome-mediated IL-1β secretion: Implications for inflammatory processes
Published in Proceedings of the National Academy of Sciences - PNAS (29-06-2004)“…Blocking the activity of IL-1β has entered the clinical arena of treating autoimmune diseases. However, a successful outcome of this approach requires a clear…”
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The nuclear protein HMGB1 is secreted by monocytes via a non-classical, vesicle-mediated secretory pathway
Published in EMBO reports (01-10-2002)“…HMGB1, a non‐histone nuclear factor, acts extracellularly as a mediator of delayed endotoxin lethality, which raises the question of how a nuclear protein can…”
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Palladium Nanoparticles Induce Disturbances in Cell Cycle Entry and Progression of Peripheral Blood Mononuclear Cells: Paramount Role of Ions
Published in Journal of immunology research (01-01-2014)“…There is concern about the possible toxicity of palladium nanoparticles (Pd-NP), as they are released in the environment through many applications. We…”
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Melanosome Transfer Promoted by Keratinocyte Growth Factor in Light and Dark Skin-Derived Keratinocytes
Published in Journal of investigative dermatology (01-03-2008)“…The transfer of melanin from melanocytes to keratinocytes is upregulated by UV radiation and modulated by autocrine and paracrine factors. Among them, the…”
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Activation of dendritic cells by tumor cell death
Published in Oncoimmunology (01-10-2012)“…A growing number of studies indicate that cell death can be either immunogenic or not, depending on its modalities, the type and the activation state of the…”
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Impact of chronic exposure to bevacizumab on EpCAM-based detection of circulating tumor cells
Published in Chinese journal of cancer research (01-10-2015)“…Background: Circulating tumor cells (CTCs) are often undetected through the immunomagnetic epithelial cell adhesion molecule (EpCAM)-based CellSearch~ System…”
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KDEL and KKXX retrieval signals appended to the same reporter protein determine different trafficking between endoplasmic reticulum, intermediate compartment, and Golgi complex
Published in Molecular biology of the cell (01-03-2003)“…Many endoplasmic reticulum (ER) proteins maintain their residence by dynamic retrieval from downstream compartments of the secretory pathway. In previous work…”
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The maturation potential of NK cell clones toward autologous dendritic cells correlates with HMGB1 secretion
Published in Journal of leukocyte biology (01-01-2007)“…Interaction of NK cells with autologous immature dendritic cells (iDCs) results in reciprocal activation. We have previously reported that NK cells trigger iDC…”
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Collagen-induced Platelet Shape Change Is Not Affected by Positive Feedback Pathway Inhibitors and cAMP-elevating Agents
Published in The Journal of biological chemistry (25-02-2005)“…Shape change is the earliest response of platelets to stimuli; it is mainly dependent upon Ca2+/calmodulin interaction subsequent to Ca2+ mobilization and is…”
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Intracellular Transport and Maturation Pathway of Human Herpesvirus 6
Published in Virology (New York, N.Y.) (10-05-1999)“…A peculiar characteristic of cells infected with human herpesvirus 6 (HHV6) is the absence of viral glycoproteins on the plasma membrane, which may reflect an…”
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Immunocytochemical Analysis of the Transfer of Vesicular Stomatitis Virus G Glycoprotein from the Intermediate Compartment to the Golgi Complex
Published in The Journal of cell biology (01-07-1992)“…We performed an immunocytochemical analysis to study the transfer of a marker protein (G glycoprotein coded by vesicular stomatitis virus ts 045 strain) from…”
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Abstract 3851: Killing of Kras mutant colon cancer cells by the αGBP cytokine, a physiological PI3K inhibitor therapeutically effective in vivo
Published in Cancer research (Chicago, Ill.) (15-04-2012)“…Abstract Activating Kras mutations are the most frequent oncogenic mutations in human cancer. Numerous downstream pathways responsible for cell proliferation…”
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Phospholipases C and A2 control lysosome-mediated IL-1beta secretion: Implications for inflammatory processes
Published in Proceedings of the National Academy of Sciences - PNAS (29-06-2004)“…Blocking the activity of IL-1beta has entered the clinical arena of treating autoimmune diseases. However, a successful outcome of this approach requires a…”
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Journal Article -
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JNK and Macroautophagy Activation by Bortezomib Has a Pro-Survival Effect in Primary Effusion Lymphoma Cells: e75965
Published in PloS one (01-09-2013)“…Understanding the mechanisms of autophagy induction and its role during chemotherapeutic treatments is of fundamental importance in order to manipulate it to…”
Get full text
Journal Article -
16
Phospholipases C and A 2 control lysosome-mediated IL-1β secretion: Implications for inflammatory processes
Published in Proceedings of the National Academy of Sciences - PNAS (29-06-2004)“…Blocking the activity of IL-1β has entered the clinical arena of treating autoimmune diseases. However, a successful outcome of this approach requires a clear…”
Get full text
Journal Article -
17
Phospholipases C and A2Control Lysosome-Mediated IL-1β Secretion: Implications for Inflammatory Processes
Published in Proceedings of the National Academy of Sciences - PNAS (29-06-2004)“…Blocking the activity of IL-1β has entered the clinical arena of treating autoimmune diseases. However, a successful outcome of this approach requires a clear…”
Get full text
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A Different Intracellular Distribution of a Single Reporter Protein Is Determined at Steady State by KKXX or KDEL Retrieval Signals
Published in The Journal of biological chemistry (09-04-1999)“…To establish the specific contribution to protein topology of KK XX and KDEL retrieval motifs, we have determined by immunogold electron microscopy and cell…”
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