Search Results - "Lott, I.T"

Alpha- and beta-secretase activity as a function of age and beta-amyloid in Down syndrome and normal brain by Nistor, M, Don, M, Parekh, M, Sarsoza, F, Goodus, M, Lopez, G.E, Kawas, C, Leverenz, J, Doran, E, Lott, I.T, Hill, M, Head, E

“…Abstract Aged individuals with Down syndrome (DS) develop Alzheimer's disease (AD) neuropathology by the age of 40 years. The purpose of the current study was…”
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Possible compensatory events in adult Down syndrome brain prior to the development of Alzheimer disease neuropathology: targets for nonpharmacological intervention by Head, E, Lott, I T, Patterson, D, Doran, E, Haier, R J

“…Adults with Down syndrome (DS) develop Alzheimer disease (AD) pathology progressively with age but clinical signs of dementia are delayed by at least 10 years…”
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Neuroimaging of individuals with Down’s syndrome at-risk for dementia: Evidence for possible compensatory events by Haier, R.J., Head, K., Head, E., Lott, I.T.

“…We report functional and structural brain indicators that may precede the onset of dementia in individuals with Down’s syndrome (DS). Middle-aged adults with…”
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Neuro-imaging of individuals with Down syndrome at-risk for dementia: evidence for possible compensatory events by Haier, RJ, Head, K, Head, E, Lott, I.T.

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β-Amyloid deposition and neurofibrillary tangle association with caspase activation in Down syndrome by Head, Elizabeth, Lott, I.T., Cribbs, David H., Cotman, Carl W., Rohn, Troy T.

“…Individuals with Down syndrome (DS) and Alzheimer's disease (AD) develop senile plaques, neurofibrillary tangles (NFT), and neuron loss. Recent studies…”
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