Search Results - "Lothar Jänsch"
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New insights into the respiratory chain of plant mitochondria. Supercomplexes and a unique composition of complex II
Published in Plant physiology (Bethesda) (01-09-2003)“…A project to systematically investigate respiratory supercomplexes in plant mitochondria was initiated. Mitochondrial fractions from Arabidopsis, potato…”
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Immune Monitoring of Human Mucosal-Associated Invariant T Cells by Quantitative Proteomics
Published in Methods in molecular biology (Clifton, N.J.) (2020)“…Molecular phenotypes of mucosal-associated invariant T (MAIT) cells are correlating with individual susceptibilities and outcomes in human diseases…”
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Mucosal-associated invariant T cells from Clostridioides difficile-infected patients exhibit a distinct proinflammatory phenotype and enhanced cytotoxic activity
Published in International immunology (07-11-2023)“…Abstract Mucosal-associated invariant T (MAIT) cells are innate-like T cells mainly found in the mucosa and peripheral blood. We have recently demonstrated…”
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Proteomic Approach to Identify Novel Mitochondrial Proteins in Arabidopsis
Published in Plant physiology (Bethesda) (01-12-2001)“…An Arabidopsis mitochondrial proteome project was started for a comprehensive investigation of mitochondrial functions in plants. Mitochondria were prepared…”
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Internal Architecture of Mitochondrial Complex I from Arabidopsis thaliana
Published in The Plant cell (01-03-2010)“…The NADH dehydrogenase complex (complex I) of the respiratory chain has unique features in plants. It is the main entrance site for electrons into the…”
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Proteogenomic Characterization of the Cement and Adhesive Gland of the Pelagic Gooseneck Barnacle Lepas anatifera
Published in International journal of molecular sciences (25-03-2021)“…We focus on the stalked goose barnacle adhesive system, an opportunistic less selective species for the substrate, found attached to a variety of floating…”
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Lipoproteins of Listeria monocytogenes Are Critical for Virulence and TLR2-Mediated Immune Activation
Published in The Journal of immunology (1950) (01-08-2008)“…Numerous cell surface components of Listeria influence and regulate innate immune recognition and virulence. Here, we demonstrate that lipidation of…”
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Translatome analyses by bio-orthogonal non-canonical amino acid labeling reveal that MR1-activated MAIT cells induce an M1 phenotype and antiviral programming in antigen-presenting monocytes
Published in Frontiers in immunology (16-02-2023)“…MAIT cells are multifunctional innate-like effector cells recognizing bacterial-derived vitamin B metabolites presented by the non-polymorphic MHC class I…”
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Quorum-Sensing Antagonistic Activities of Azithromycin in Pseudomonas aeruginosa PAO1: a Global Approach
Published in Antimicrobial Agents and Chemotherapy (01-05-2006)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Towards the characterization of the hidden world of small proteins in Staphylococcus aureus, a proteogenomics approach
Published in PLoS genetics (01-06-2021)“…Small proteins play essential roles in bacterial physiology and virulence, however, automated algorithms for genome annotation are often not yet able to…”
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Moonlighting chaperone activity of the enzyme PqsE contributes to RhlR-controlled virulence of Pseudomonas aeruginosa
Published in Nature communications (01-12-2022)“…Pseudomonas aeruginosa is a major cause of nosocomial infections and also leads to severe exacerbations in cystic fibrosis or chronic obstructive pulmonary…”
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Genomewide Identification of Genetic Determinants of Antimicrobial Drug Resistance in Pseudomonas aeruginosa
Published in Antimicrobial Agents and Chemotherapy (01-06-2009)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Clarithromycin Exerts an Antibiofilm Effect against Salmonella enterica Serovar Typhimurium rdar Biofilm Formation and Transforms the Physiology towards an Apparent Oxygen-Depleted Energy and Carbon Metabolism
Published in Infection and immunity (19-10-2020)“…Upon biofilm formation, production of extracellular matrix components and alteration in physiology and metabolism allows bacteria to build up multicellular…”
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Proteomic analysis of plasma-derived extracellular vesicles: pre- and postprandial comparisons
Published in Scientific reports (03-10-2024)“…Extracellular vesicles (EVs) are key in intercellular communication, carrying biomolecules like nucleic acids, lipids, and proteins. This study investigated…”
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Chronic Toxoplasma infection is associated with distinct alterations in the synaptic protein composition
Published in Journal of neuroinflammation (01-08-2018)“…Chronic infection with the neurotropic parasite Toxoplasma gondii has been implicated in the risk for several neuropsychiatric disorders. The mechanisms, by…”
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Protein Network of the Pseudomonas aeruginosa Denitrification Apparatus
Published in Journal of bacteriology (01-05-2016)“…Oxidative phosphorylation using multiple-component, membrane-associated protein complexes is the most effective way for a cell to generate energy. Here, we…”
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Modulating the Molybdenum Coordination Sphere of Escherichia coli Trimethylamine N‑Oxide Reductase
Published in Biochemistry (Easton) (20-02-2018)“…The well-studied enterobacterium Escherichia coli present in the human gut can reduce trimethylamine N-oxide (TMAO) to trimethylamine during anaerobic…”
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The Role of Neutral Sphingomyelinase-2 (NSM2) in the Control of Neutral Lipid Storage in T Cells
Published in International journal of molecular sciences (01-03-2024)“…The accumulation of lipid droplets (LDs) and ceramides (Cer) is linked to non-alcoholic fatty liver disease (NAFLD), regularly co-existing with type 2 diabetes…”
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Dynamic changes in the proximitome of neutral sphingomyelinase-2 (nSMase2) in TNFα stimulated Jurkat cells
Published in Frontiers in immunology (09-07-2024)“…Ceramides generated by the activity of the neutral sphingomyelinase 2 (nSMase2) play a pivotal role in stress responses in mammalian cells. Dysregulation of…”
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Proteome analysis of human CD56neg NK cells reveals a homogeneous phenotype surprisingly similar to CD56dim NK cells
Published in European journal of immunology (01-09-2018)“…NK cells lacking CD56 (CD56neg) were first identified in chronic HIV‐1 infection. However, CD56neg NK cells also exist in healthy individuals, albeit in…”
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