Search Results - "Lotesoriere, Claudio"

Molecular mechanisms of synergistic action of Ramucirumab and Paclitaxel in Gastric Cancers cell lines by Refolo, Maria Grazia, Lotesoriere, Claudio, Lolli, Ivan Roberto, Messa, Caterina, D’Alessandro, Rosalba

“…Ramucirumab is approved both as monotherapy and in combination with Paclitaxel for advanced gastric cancer in patients with disease progression after…”
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Autotaxin-Lysophosphatidate Axis: Promoter of Cancer Development and Possible Therapeutic Implications by Laface, Carmelo, Ricci, Angela Dalia, Vallarelli, Simona, Ostuni, Carmela, Rizzo, Alessandro, Ambrogio, Francesca, Centonze, Matteo, Schirizzi, Annalisa, De Leonardis, Giampiero, D'Alessandro, Rosalba, Lotesoriere, Claudio, Giannelli, Gianluigi

“…Autotaxin (ATX) is a member of the ectonucleotide pyrophosphate/phosphodiesterase ( ) family; it is encoded by the gene. ATX is a secreted glycoprotein and…”
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Corrigendum: Variations in circulating levels of angiopoietin-2 over time are predictive of ramucirumab-paclitaxel therapy outcome in advanced gastric cancer: results of prospective study by D'Alessandro, Rosalba, Refolo, Maria Grazia, Schirizzi, Annalisa, De Leonardis, Giampiero, Donghia, Rossella, Guerra, Vito, Giannelli, Gianluigi, Lolli, Ivan Roberto, Laterza, Maria Maddalena, De Vita, Ferdinando, Messa, Caterina, Lotesoriere, Claudio

“…[This corrects the article DOI: 10.3389/fonc.2022.862116.]…”
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Variations in Circulating Levels of Angiopoietin-2 Over Time Are Predictive of Ramucirumab-Paclitaxel Therapy Outcome in Advanced Gastric Cancer: Results of Prospective Study by D'Alessandro, Rosalba, Refolo, Maria Grazia, Schirizzi, Annalisa, De Leonardis, Giampiero, Donghia, Rossella, Guerra, Vito, Giannelli, Gianluigi, Lolli, Ivan Roberto, Laterza, Maria Maddalena, De Vita, Ferdinando, Messa, Caterina, Lotesoriere, Claudio

“…The combination of paclitaxel and ramucirumab is the second-line therapy of choice in the treatment of advanced gastric cancer. To date, no biomarkers are…”
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The multiple combination of Paclitaxel, Ramucirumab and Elacridar reverses the paclitaxel-mediated resistance in gastric cancer cell lines by Schirizzi, Annalisa, Contino, Marialessandra, Carrieri, Livianna, Riganti, Chiara, De Leonardis, Giampiero, Scavo, Maria Principia, Perrone, Maria Grazia, Miciaccia, Morena, Kopecka, Joanna, Refolo, Maria Grazia, Lotesoriere, Claudio, Depalo, Nicoletta, Rizzi, Federica, Giannelli, Gianluigi, Messa, Caterina, D'Alessandro, Rosalba

“…Paclitaxel (PTX) interferes with microtubule architecture by binding to β-tubulin, thereby blocking progression at the G2/M phase and inducing apoptosis. This…”
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Frizzled-10 Extracellular Vesicles Plasma Concentration Is Associated with Tumoral Progression in Patients with Colorectal and Gastric Cancer by Lotesoriere, Claudio, Panarese, Alba, Giannelli, Gianluigi, Curri, Maria Lucia, Laquintana, Valentino, Denora, Nunzio, Bianco, Maria Grazia, Fanizza, Elisabetta, Depalo, Nicoletta, Cigliano, Antonio, Scavo, Maria Principia, Lorusso, Dionigi

“…Extracellular vesicles (EVs) are involved in intercellular communication during the carcinogenesis. Our attention has been focused on small EVs (sEVs) protein…”
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VEGFA Status as a Predictive Marker of Therapy Outcome in Metastatic Gastric Cancer Patients Following Ramucirumab-Based Treatment by Schirizzi, Annalisa, Arshadi, Aram, Tolomeo, Doron, Schirosi, Laura, Valentini, Anna Maria, De Leonardis, Giampiero, Refolo, Maria Grazia, Donghia, Rossella, Storlazzi, Clelia Tiziana, Zito, Alfredo, Ricci, Angela Dalia, Vallarelli, Simona, Ostuni, Carmela, Bencivenga, Maria, De Manzoni, Giovanni, Messa, Caterina, Armentano, Raffaele, Giannelli, Gianluigi, Lotesoriere, Claudio, D'Alessandro, Rosalba

“…Metastatic gastric cancer (mGC) often has a poor prognosis and may benefit from a few targeted therapies. Ramucirumab-based anti-angiogenic therapy targeting…”
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Characterization of a rare variant (c.2635-2A>G) of the MSH2 gene in a family with Lynch syndrome by Cariola, Filomena, Disciglio, Vittoria, Valentini, Anna M., Lotesoriere, Claudio, Fasano, Candida, Forte, Giovanna, Russo, Luciana, Di Carlo, Antonio, Guglielmi, Floranna, Manghisi, Andrea, Lolli, Ivan, Caruso, Maria L., Simone, Cristiano

“…Introduction: Lynch syndrome is caused by germline mutations in one of the mismatch repair genes (MLH1, MSH2, MSH6, and PMS2) or in the EPCAM gene. Lynch…”
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Basal and bevacizumab-based therapy-induced changes of lactate dehydrogenases and fibrinogen levels and clinical outcome of previously untreated metastatic colorectal cancer patients: a multicentric retrospective analysis by Silvestris, Nicola, Scartozzi, Mario, Graziano, Giusi, Santini, Daniele, Lorusso, Vito, Maiello, Evaristo, Barni, Sandro, Cinieri, Saverio, Loupakis, Fotios, Pisconti, Salvatore, Brunetti, Anna Elisabetta, Palasciano, Giuseppe, Palmieri, Vincenzo Ostilio, Del Prete, Michela, Dell'Aquila, Emanuela, Latiano, Tiziana Pia, Petrelli, Fausto, Lutrino, Stefania, Rossini, Daniele, Giampieri, Riccardo, Lotesoriere, Claudio, Cascinu, Stefano

“…To assess the predictive role of lactate dehydrogenases (LDH) and fibrinogen (FBG) serum levels in metastatic colorectal cancer (mCRC) patients receiving a…”
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Hepatitis C Virus Infection Involves CD34+Hematopoietic Progenitor Cells in Hepatitis C Virus Chronic Carriers by Sansonno, Domenico, Lotesoriere, Claudio, Cornacchiulo, Vito, Fanelli, Massimo, Gatti, Pietro, Iodice, Giuseppe, Racanelli, Vito, Dammacco, Franco

“…Although hepatitis C virus (HCV) mainly affects hepatocytes, infection is widespread and involves immunologically privileged sites. Whether lymphoid cells…”
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Integrated immune gene expression signature and molecular classification in gastric cancer: New insights by Refolo, Maria Grazia, Lotesoriere, Claudio, Messa, Caterina, Caruso, Maria Gabriella, D'Alessandro, Rosalba

“…Gastric cancer (GC) is characterized by extreme heterogeneity due to histopathological differences, molecular characteristics, and immune gene expression…”
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Immunotherapy in biliary tract cancer: are we finally on the right path? by Ricci, Angela Dalia, Rizzo, Alessandro, Lotesoriere, Claudio

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High levels of autotaxin and lysophosphatidic acid predict poor outcome in treatment of resectable gastric carcinoma by Schirizzi, Annalisa, Donghia, Rossella, De Nunzio, Valentina, Renna, Natasha, Centonze, Matteo, De Leonardis, Giampiero, Lorusso, Vincenza, Fantasia, Alessia, Coletta, Sergio, Stabile, Dolores, Ferro, Annalisa, Notarnicola, Maria, Ricci, Angela D., Lotesoriere, Claudio, Lahn, Michael, D’Alessandro, Rosalba, Giannelli, Gianluigi

“…Although early-stage gastric cancer is a candidate for curative surgical resection, the absence of specific early symptoms results in a late diagnosis and…”
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Tumor Immune Microenvironment in Intrahepatic Cholangiocarcinoma: Regulatory Mechanisms, Functions, and Therapeutic Implications by Ricci, Angela Dalia, Rizzo, Alessandro, Schirizzi, Annalisa, D'Alessandro, Rosalba, Frega, Giorgio, Brandi, Giovanni, Shahini, Endrit, Cozzolongo, Raffaele, Lotesoriere, Claudio, Giannelli, Gianluigi

“…Treatment options for intrahepatic cholangiocarcinoma (iCCA), a highly malignant tumor with poor prognosis, are limited. Recent developments in immunotherapy…”
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Durvalumab in advanced cholangiocarcinoma: is someone knocking down the door? by Ricci, Angela Dalia, D'Alessandro, Rosalba, Rizzo, Alessandro, Schirizzi, Annalisa, Vallarelli, Simona, Ostuni, Carmela, Troiani, Laura, Lolli, Ivan Roberto, Lotesoriere, Claudio, Giannelli, Gianluigi

“…Following the practice-changing results observed in several hematological and solid tumors, immunotherapy with immune checkpoint inhibitors (ICIs) has been…”
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Sarcoidosis mimicking metastatic progression of pancreatic neuroendocrine tumor: A case report by Lolli, Ivan, Stasi, Elisa, Fucilli, Fabio, Pirrelli, Michele, Armentano, Raffaele, Campanella, Giovanna, Lotesoriere, Claudio, Lorusso, Dionigi

“…Pancreatic neuroendocrine tumors (PNETs) account for less than 5% of all pancreatic tumors. PNETs develop from pancreatic endocrine islet cells and have a…”
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Targeting Angiogenesis in the Era of Biliary Tract Cancer Immunotherapy: Biological Rationale, Clinical Implications, and Future Research Avenues by Schirizzi, Annalisa, De Leonardis, Giampiero, Lorusso, Vincenza, Donghia, Rossella, Rizzo, Alessandro, Vallarelli, Simona, Ostuni, Carmela, Troiani, Laura, Lolli, Ivan Roberto, Giannelli, Gianluigi, Ricci, Angela Dalia, D'Alessandro, Rosalba, Lotesoriere, Claudio

“…Although biliary tract cancers are traditionally considered rare in Western countries, their incidence and mortality rates are rising worldwide. A better…”
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The Italian Rare Biliary tract Cancer initiative (IRaBiCa): A multicentric observational study of Gruppo Oncologico dell’Italia Meridionale (GOIM) in collaboration with Gruppo Italiano Colangiocarcinoma (GICO) by Speranza, Desirèe, Sapuppo, Elena, Aprile, Giuseppe, Auriemma, Alessandra, Bergamo, Francesca, Bianco, Roberto, Bordonaro, Roberto, Brandi, Giovanni, Brunetti, Oronzo, Carnaghi, Carlo, Ciliberto, Domenico, Cinieri, Saverio, Corallo, Salvatore, De Vita, Ferdinando, Di Donato, Samantha, Ferraù, Francesco, Fornaro, Lorenzo, Barucca, Viola, Giommoni, Elisa, Lotesoriere, Claudio, Luchini, Claudio, Masini, Cristina, Niger, Monica, Pisconti, Salvatore, Rapposelli, Ilario Giovanni, Rimassa, Lorenza, Rognone, Chiara, Rodriquenz, Maria Grazia, Corsini, Lidia Rita, Santin, Daniele, Scarpa, Aldo, Scartozzi, Mario, Soto Parra, Hector, Tonini, Giuseppe, Tortora, Giampaolo, Tralongo, Paolo, Silvestris, Nicola

“…Introduction: About 90% of cholangiocarcinomas are adenocarcinomas with glandular or tubular structures lined by epithelial cells, with no bile production and…”
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Identification and Somatic Characterization of the Germline PTEN Promoter Variant rs34149102 in a Family with Gastrointestinal and Breast Tumors by Disciglio, Vittoria, Sanese, Paola, Fasano, Candida, Lotesoriere, Claudio, Valentini, Anna Maria, Forte, Giovanna, Lepore Signorile, Martina, De Marco, Katia, Grossi, Valentina, Lolli, Ivan, Cariola, Filomena, Simone, Cristiano

“…Genetic variants located in non-coding regions can affect processes that regulate protein expression, functionally contributing to human disease. Germline…”
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Abstract 3700: Genomic alterations on first-line panitumumab plus FOLFIRI in metastatic colorectal cancer by Avallone, Antonio, Giuliani, Francesco, Nasti, Guglielmo, Montesarchio, Vincenzo, Santabarbara, Giuseppe, Leo, Silvana, Malapelle, Umberto, Rosati, Gerardo, Lotesoriere, Claudio, Tamburini, Emiliano, Colombo, Alfredo, Pepe, Francesco, Cardone, Claudia, Leone, Alessandra, Vitagliano, Carlo, Russo, Gianluca, Troncone, Giancarlo, Giannarelli, Diana, De Stefano, Alfonso, Budillon, Alfredo

“…Abstract Background: IMPROVE is a randomized, non-comparative multicenter, phase 2 study evaluating continuous or intermittent FOLFIRI/PANI, in first-line in…”
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