Search Results - "Losey, H.C."

1661P Antitumor efficacy and immune profiling of the mouse ortholog of nemvaleukin alfa, a novel engineered IL-2 fusion protein, in an orthotopic mouse model of small cell lung cancer alone or in combination with standard chemotherapy by Pan, Y., Zhang, H., Chen, T., Ding, H., Han, H., Almonte, C., Labbe, K.E., Nguyen, S., Lopes, J.E., Losey, H.C., Winquist, R.J., Wong, K-K.

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1027MO ALKS 4230 monotherapy and in combination with pembrolizumab (pembro) in patients (pts) with refractory solid tumours (ARTISTRY-1) by Vaishampayan, U.N., Muzaffar, J., Velcheti, V., Winer, I., Hoimes, C.J., Rosen, S.D., Spreafico, A., McDermott, D.F., Chu, Q.S-C., Dumas, O., Gilbert, L., Hirte, H., Curtis, K.K., Du, Y., Bidollari, I., Sun, L., Putiri, E., Losey, H.C., Dezube, B., Ernstoff, M.S.

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Crystal Structure of Vancosaminyltransferase GtfD from the Vancomycin Biosynthetic Pathway: Interactions with Acceptor and Nucleotide Ligands by Mulichak, A.M., Lu, W., Losey, H.C., Walsh, C.T., Garavito, R.M.

“…The TDP-vancosaminyltransferase GtfD catalyzes the attachment of L-vancosamine to a monoglucosylated heptapeptide intermediate during the final stage of…”
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The Structural Basis for Induction of VanB Resistance by Dong, Steven D, Oberthür, Markus, Losey, Heather C, Anderson, John W, Eggert, Ulrike S, Peczuh, Mark W, Walsh, Christopher T, Kahne, Daniel

“…Because teicoplanin and vancomycin are the last line of defense for many bacterial infections, the emergence of resistance to glycopeptide antibiotics in…”
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Antibiotic glycosyltransferases by Walsh, C T, Losey, H C, Freel Meyers, C L

“…In the biosynthesis of several classes of antibiotics, sugars are attached to aglycone scaffolds by antibiotic-specific glycosyltransferases in the latter…”
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