Search Results - "Loscher, Christine E."

Autoantibodies - enemies, and/or potential allies? by Ma, Hui, Murphy, Caroline, Loscher, Christine E, O'Kennedy, Richard

“…Autoantibodies are well known as potentially highly harmful antibodies which attack the host binding to self-antigens, thus causing severe associated diseases…”
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A role for TLR4 in Clostridium difficile infection and the recognition of surface layer proteins by Ryan, Anthony, Lynch, Mark, Smith, Sinead M, Amu, Sylvie, Nel, Hendrik J, McCoy, Claire E, Dowling, Jennifer K, Draper, Eve, O'Reilly, Vincent, McCarthy, Ciara, O'Brien, Julie, Ní Eidhin, Déirdre, O'Connell, Mary J, Keogh, Brian, Morton, Charles O, Rogers, Thomas R, Fallon, Padraic G, O'Neill, Luke A, Kelleher, Dermot, Loscher, Christine E

“…Clostridium difficile is the etiological agent of antibiotic-associated diarrhoea (AAD) and pseudomembranous colitis in humans. The role of the surface layer…”
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Antidiabetic Effects of cis-9, trans-11–Conjugated Linoleic Acid May Be Mediated via Anti-Inflammatory Effects in White Adipose Tissue by MOLONEY, Fiona, TOOMEY, Sinead, NOONE, Enda, NUGENT, Anne, ALLAN, Bernard, LOSCHER, Christine E, ROCHE, Helen M

“…Antidiabetic Effects of cis -9, trans -11–Conjugated Linoleic Acid May Be Mediated via Anti-Inflammatory Effects in White Adipose Tissue Fiona Moloney 1 ,…”
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Fasciola hepatica Tegumental Antigen Suppresses Dendritic Cell Maturation and Function by Hamilton, Clare M, Dowling, David J, Loscher, Christine E, Morphew, Russell M, Brophy, Peter M, O'Neill, Sandra M

“…Parasitic worms and molecules derived from them have powerful anti-inflammatory properties and are shown to have therapeutic effects on inflammatory diseases…”
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Novel Dairy Fermentates Have Differential Effects on Key Immune Responses Associated with Viral Immunity and Inflammation in Dendritic Cells by Finnegan, Dearbhla, Connolly, Claire, Mechoud, Monica A, FitzGerald, Jamie A, Beresford, Tom, Mathur, Harsh, Brennan, Lorraine, Cotter, Paul D, Loscher, Christine E

“…Fermented foods and ingredients, including furmenties derived from lactic acid bacteria (LAB) in dairy products, can modulate the immune system. Here, we…”
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The effects of dairy on the gut microbiome and symptoms in gastrointestinal disease cohorts: a systematic review by Ní Chonnacháin, Clíona, Feeney, Emma L, Gollogly, Clare, Shields, Denis C, Loscher, Christine E, Cotter, Paul D, Noronha, Nessa, Stack, Roisin, Doherty, Glen A, Gibney, Eileen R

“…Bovine dairy foods provide several essential nutrients. Fermented bovine dairy foods contain additional compounds, increasing their potential to benefit…”
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A role for syntaxin 3 in the secretion of IL-6 from dendritic cells following activation of toll-like receptors by Collins, Laura E, DeCourcey, Joseph, Rochfort, Keith D, Kristek, Maja, Loscher, Christine E

“…The role of dendritic cells (DCs) in directing the immune response is due in part to their capacity to produce a range of cytokines. Importantly, DCs are a…”
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Erratum to: Surface layer proteins from virulent Clostridium difficile ribotypes exhibit signatures of positive selection with consequences for innate immune response by Lynch, Mark, Walsh, Thomas A, Marszalowska, Izabela, Webb, Andrew E, Mac Aogáin, Micheál, Rogers, Thomas R, Windle, Henry, Kelleher, Dermot, O'Connell, Mary J, Loscher, Christine E

“…“Upon publication of the original article [1], it was noticed that there was an error in the author name. The author’s name should be "Micheal Mac Aogain"…”
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Synthesis and Biological Evaluation of Pyridine-Containing Lipoxin A4 Analogues by Duffy, Colm D., Maderna, Paola, McCarthy, Ciara, Loscher, Christine E., Godson, Catherine, Guiry, Patrick J.

“…A short and efficient synthesis of new pyridine‐containing lipoxin A4 analogues was developed. These analogues induce phagocytosis of apoptotic…”
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An Emerging Role for SNARE Proteins in Dendritic Cell Function by Collins, Laura E, DeCourcey, Joseph, Soledad di Luca, Mariana, Rochfort, Keith D, Loscher, Christine E

“…Dendritic cells (DCs) provide an essential link between innate and adaptive immunity. At the site of infection, antigens recognized by DCs via…”
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Anti-inflammatory effects of EPA and DHA are dependent upon time and dose-response elements associated with LPS stimulation in THP-1-derived macrophages by Mullen, Anne, Loscher, Christine E., Roche, Helen M.

“…The long-chain n-3 polyunsaturated fatty acids (LC n-3 PUFA) of fish oil, eicosapentanoic (EPA) and docosahexanoic (DHA) acids are considered cardioprotective…”
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Colon cancer associated genes exhibit signatures of positive selection at functionally significant positions by Morgan, Claire C, Shakya, Kabita, Webb, Andrew, Walsh, Thomas A, Lynch, Mark, Loscher, Christine E, Ruskin, Heather J, O'Connell, Mary J

“…Cancer, much like most human disease, is routinely studied by utilizing model organisms. Of these model organisms, mice are often dominant. However, our…”
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Conjugated linoleic acid suppresses IRF3 activation via modulation of CD14 by Dowling, Jennifer K, McCoy, Claire E, Doyle, Sarah L, BenLarbi, Nadia, Canavan, Mary, O'Neill, Luke A, Loscher, Christine E

“…Polyunsaturated fatty acids (PUFA) can modulate the immune response, however the mechanism by which they exert this effect remains unclear. Previous studies…”
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Proinflammatory Responses in the Murine Brain after Intranasal Delivery of Cholera Toxin: Implications for the Use of AB Toxins as Adjuvants in Intranasal Vaccines by Armstrong, Michelle E. , Lavelle, Ed C. , Loscher, Christine E. , Lynch, Marina A. , Mills, Kingston H. G. 

“…Intranasal delivery of vaccines provides an attractive alternative to parenteral delivery, but it requires appropriate mucosal adjuvants. Cholera toxin (CT) is…”
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Omega-3 fatty acids attenuate dendritic cell function via NF-κB independent of PPARγ by Draper, Eve, Reynolds, Clare M, Canavan, Mary, Mills, Kingston H, Loscher, Christine E, Roche, Helen M

“…Long-chain n-3 polyunsaturated fatty acids (n-3 PUFA) have been shown to modulate the immune response and have therapeutic effects in inflammatory disorders…”
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Docosahexaenoic acid induces an anti-inflammatory profile in lipopolysaccharide-stimulated human THP-1 macrophages more effectively than eicosapentaenoic acid by Weldon, Sinéad M., Mullen, Anne C., Loscher, Christine E., Hurley, Lisa A., Roche, Helen M.

“…A number of studies have investigated the effects of fish oil on the production of pro-inflammatory cytokines using peripheral blood mononuclear cell models…”
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Interleukin-1 receptor antagonist exerts agonist activity in the hippocampus independent of the interleukin-1 type I receptor by Loscher, Christine E., Mills, Kingston H.G., Lynch, Marina A.

“…Interleukin-1 receptor antagonist (IL-1ra) selectively and competitively inhibits the actions of IL-1 at its receptors and has not been reported to have…”
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Whole-Cell but Not Acellular Pertussis Vaccines Induce Convulsive Activity in Mice: Evidence of a Role for Toxin-Induced Interleukin-1β in a New Murine Model for Analysis of Neuronal Side Effects of Vaccination by DONNELLY, Sheila, LOSCHER, Christine E, LYNCH, Marina A, MILLS, Kingston H. G

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Adaptive Evolution as a Predictor of Species-Specific Innate Immune Response by Webb, Andrew E, Gerek, Z Nevin, Morgan, Claire C, Walsh, Thomas A, Loscher, Christine E, Edwards, Scott V, O'Connell, Mary J

“…It has been proposed that positive selection may be associated with protein functional change. For example, human and macaque have different outcomes to HIV…”
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Adaptive Evolution in TRIF Leads to Discordance between Human and Mouse Innate Immune Signaling by Hyland, Edel M, Webb, Andrew E, Kennedy, Kathy F, Gerek Ince, Z Nevin, Loscher, Christine E, O’Connell, Mary J

“…Abstract The TIR domain-containing adapter inducing IFN-β (TRIF) protein is an innate immune system protein that mediates the MyD88-independent toll-like…”
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